Midwife Patience Murphy has a gift: a talent for escorting mothers through the challenges of bringing children into the world. Working in the hardscrabble conditions of Appalachia during the Depression, Patience takes the jobs that no one else wants, helping those most in need - and least likely to pay. She knows a successful midwifery practice must be built on a foundation of openness and trust - but the secrets Patience is keeping are far too intimate and fragile for her to ever let anyone in.

In a bid to outrun her past, Carrie Ballentyne accepts a nursing position with a doctor in the New Mexico Territory. She knows the journey from New York to Santa Fe will not be easy, but she relishes the adventure. However, nothing could have prepared her for the wilderness she encounters. Its vastness and power are awe-inspiring, stunning in both beauty and brutality. To endure, she must learn to rely on her fellow travelers—and one enigmatic man in particular. As the small, tight-knit group tackles challenge after challenge, she feels her heart opening to this rugged land.

Between the urban bustle of Denver and the high-stress environment of a career in neurosurgery, Maggie Sullivan has hit a wall. When an emergency high-risk procedure results in the death of a teenager, Maggie finds herself in the middle of a lawsuit - and experiencing levels of anxiety she's never faced before. She knows she needs to slow down before she burns out completely, and the best place she can think to do that is Sullivan's Crossing.

The Birth House is the story of Dora Rare, the first daughter to be born in five generations of Rares. As a child in an isolated village in Nova Scotia, she is drawn to Miss Babineau, an outspoken Acadian midwife with a gift for healing. Dora becomes Miss B.’s apprentice, and together they help the women of Scots Bay through infertility, difficult labours, breech births, unwanted pregnancies and even unfulfilling sex lives.

Reluctant midwife Emma Trimpany is just 17 when she assists at the harrowing birth of the Dionne quintuplets: five tiny miracles born to French farmers in hardscrabble Northern Ontario in 1934. Emma cares for them through their perilous first days, and when the government decides to remove the babies from their francophone parents, making them wards of the British king, Emma signs on as their nurse.