Midwife Patience Murphy has a gift: a talent for escorting mothers through the challenges of bringing children into the world. Working in the hardscrabble conditions of Appalachia during the Depression, Patience takes the jobs that no one else wants, helping those most in need - and least likely to pay. She knows a successful midwifery practice must be built on a foundation of openness and trust - but the secrets Patience is keeping are far too intimate and fragile for her to ever let anyone in.

Between the urban bustle of Denver and the high-stress environment of a career in neurosurgery, Maggie Sullivan has hit a wall. When an emergency high-risk procedure results in the death of a teenager, Maggie finds herself in the middle of a lawsuit - and experiencing levels of anxiety she's never faced before. She knows she needs to slow down before she burns out completely, and the best place she can think to do that is Sullivan's Crossing.

The Birth House is the story of Dora Rare, the first daughter to be born in five generations of Rares. As a child in an isolated village in Nova Scotia, she is drawn to Miss Babineau, an outspoken Acadian midwife with a gift for healing. Dora becomes Miss B.’s apprentice, and together they help the women of Scots Bay through infertility, difficult labours, breech births, unwanted pregnancies and even unfulfilling sex lives.

Reluctant midwife Emma Trimpany is just 17 when she assists at the harrowing birth of the Dionne quintuplets: five tiny miracles born to French farmers in hardscrabble Northern Ontario in 1934. Emma cares for them through their perilous first days, and when the government decides to remove the babies from their francophone parents, making them wards of the British king, Emma signs on as their nurse.

Berlin Zoo, 1943: Ten-year-old Adelaide and her newborn sister are orphaned after a devastating night of bombing. Heartbroken and frightened, Adelaide runs to her mother’s closest friend, Katharina Heinroth, and the kind zookeeper takes the two little girls under her protection. As the bombing intensifies, Adelaide tries to shut out the horrors of war by caring for her tiny sister and playing with the adorable baby monkeys. But when Katharina organizes a dangerous operation to enable children and animals to escape the battle-scarred city, something goes wrong.