The fate of the entire Marvel Universe hangs in the balance as Earth's mightiest heroes face their greatest challenge! Summoned across the stars by the mysterious and unbelievably powerful Beyonder, the Avengers, Spider-Man, the Fantastic Four, and the X-Men are set against their deadliest foes on the mysterious planet known as Battleworld - with the winner promised the ultimate prize. But as battle lines are drawn, new alliances are forged, and old enemies clash, one among them is not willing to settle for anything less than godhood.

Iron Man and Captain America are two core members of the Avengers, the world's greatest superhero team. But when a tragic battle blows a hole in the city of Stamford, killing hundreds of people, the US government demands that all superheroes unmask and register their powers. To Tony Stark - Iron Man - it's a regrettable but necessary step. To Captain America, it's an unbearable assault on civil liberties.

Under secret orders to assassinate the Widow, Hawkeye, the rough-edged marksman, finds himself caught up in a violent prison break that releases some of the world's most vicious and powerful criminals. Defying his superiors, Hawkeye joins forces with the sultry Russian spy and a mismatched group of personalities that include Spider-Man, Spider-Woman, Luke Cage, Captain America, and Iron Man.

No evildoers have tried to flatten Peter Parker in weeks. His marriage to Mary Jane is stronger than ever, and he's enjoying his job as a high-school science teacher. Life is good. Naturally, that doesn't last. When Peter learns that his old enemy, the Rhino, is on a rampage in Times Square, he suits up as Spider-Man to stop the destructive villain in his tracks. But he's unexpectedly foiled in his attempts by the Black Cat, a former ally and old flame. The Cat informs Peter that the Rhino is just a distraction - the real threat comes from a group of Ancients.

Thor—Son of Odin, God of Thunder, wielder of the hammer Mjolnir—is dead. And Loki is responsible. It was only meant to be a joke—tampering with the Destroyer, changing Thor’s course to Midgard—a bit of mischief with a chance of maiming. But Loki's harmless prank spiraled out of control, unleashing death and destruction on New York City and the heroes sworn to protect it. The city was saved, but at the cost of Thor’s life.

Hydra has a synthetic pathogen that will make the entire human race dependent on them for the cure. A.I.M.'s newly developed nanotech compound to enslave humanity is dangerously close to contaminating the world's water supplies. Ultron is poised on the edge of Singularity, Earth's technology at his metallic fingertips. Dormammu has a plan to save the world - by claiming it as his own. The High Evolutionary is rewriting the human genome in a bid to turn humankind into a eugenic slave-race. Everybody wants to rule the world - and only the isolated Avengers can stop them.

The Avengers journey into deep space, where they unite the intergalactic races against the Builders - deadly aliens who seek to destroy the known galaxy. While the heroes are gone, Thanos sets his sights on Earth, sending the Black Order to launch the assault. It falls to the other heroes of Earth - the Inhumans, the Black Panther, Namor the Sub-Mariner, Doctor Strange, the X-Men, and more - to defend Attilan, Wakanda, Atlantis, and the rest of the planet. To defeat Thanos, the defending forces will need to deploy a new weapon - one that may be as deadly as the invading force.

Betrayed by Earth's heroes and exiled into outer space, the man-monster known as the Incredible Hulk has landed on the distant planet Sakaar, ruled by the tyrannical Red King. Sold into slavery, the Hulk becomes the Green Scar, the planet's mightiest gladiator! But his new masters get more than they bargained for when he forges a bond of brotherhood with his fellow fighters: crafty insectoid Miek, the horrific Brood, wise rock-man Korg, Shadow Warrior Hiroim, noble-born rebel Elloe, and her loyal guardsman Skee. Together, these gladiators start a revolution.

Peter Parker is caught in a complicated web. Working in a cutting-edge laboratory, he's a young scientist who's trying to make a difference. Yet he's constantly burdened by the responsibilities of his second career as the crime-fighting Spider-Man. Wilson Fisk - the so-called Kingpin of Crime - has returned to New York, establishing himself publicly as an altruistic entrepreneur and philanthropist. Spider-Man knows better, but he can't uncover Fisk's scheme, which, if executed, will make the crime lord too big to fail.

While visiting Japan, Wolverine is recruited to recover a stolen experimental drug, one that has the potential to be a true miracle cure for all human disease - or a sadistic means of enslaving the world. With every hour bringing mankind closer to tragedy, he embarks on a daring mission to identify the thieves and thwart their terrifying agenda.