A writer in California. A doctor in Boston. A motel owner and his employee in Nevada. A priest in Chicago. A robber in New York. A little girl in Las Vegas. They’re a handful of people from across the country, living through eerie variations of the same nightmare.

Raised in the wilderness by her late great-uncle, Vida is a young woman with an almost preternatural affinity for nature, especially for the wolves that also call the forested mountains home. Formed by hard experience, by love and loss, and by the prophecies of a fortuneteller, Vida just wants peace. If only nearby Kettleton County didn’t cast such a dark shadow.

Bartholomew Lampion is born on a day of tragedy and terror that will mark his family forever. All agree that his unusual eyes are the most beautiful they have ever seen. On this same day, a thousand miles away, a ruthless man learns that he has a mortal enemy named Bartholomew. He embarks on a relentless search to find this enemy, a search that will consume his life. And a girl is born from a brutal rape, her destiny mysteriously linked to Barty and the man who stalks him.

Benny Catspaw’s perpetually sunny disposition is tested when he loses his job, his reputation, his fiancée, and his favorite chair. He’s not paranoid. Someone is out to get him. He just doesn’t know who or why. Then Benny receives an inheritance from an uncle he’s never heard of: a giant crate and a video message. All will be well in time.

In retreat from a devastating loss and crushing injustice, Katie lives alone in a fortresslike stone house on Jacob’s Ladder island. Once a rising star in the art world, she finds refuge in her painting. The neighboring island of Ringrock houses a secret: a government research facility. And now two agents have arrived on Jacob’s Ladder in search of someone—or something—they refuse to identify. Although an air of menace hangs over these men, an infinitely greater threat has arrived, one so strange even the island animals are in a state of high alarm.