In a dimly lit cell, a man has awakened to find himself surrounded by the most unimaginable and barbaric things that not even his worst nightmare could conjure up. His captor, Seth Coker, takes the man on a journey into his twisted world of vengeance. A world that runs parallel with the horrors that could only be found in the deepest and darkest parts of hell. A world that bestows a wrath of chaos upon the wicked of our society who have fallen through the cracks of the judicial system. Seth wasn't born a vigilante, nor did he seek out the role—it sought him out.

Tamsen Donner must be a witch. That is the only way to explain the series of misfortunes that have plagued the wagon train known as the Donner Party. Depleted rations, bitter quarrels, and the mysterious death of a little boy have driven the pioneers to the brink of madness. They cannot escape the feeling that someone—or something—is stalking them. Whether it was a curse from the beautiful Tamsen, the choice to follow an experimental route West, or just bad luck - the 90 men, women, and children of the Donner Party are at the brink of one of the deadliest adventures in history.

Welcome to Hopkins Bend, the remote little Tennessee town where the backwoods inhabitants are cannibals and the local law operates a sex-trafficking ring. Unlucky travelers are frequently ensnared in the town’s sinister web. Some are held captive and tortured while others face even more gruesome fates. And beneath it all is the town’s darkest secret, the curse of the depraved and mutated Kincher clan.

Working at the local processing plant, Marcos is in the business of slaughtering humans - though no one calls them that anymore. His wife has left him, his father is sinking into dementia, and Marcos tries not to think too hard about how he makes a living. After all, it happened so quickly. First, it was reported that an infectious virus has made all animal meat poisonous to humans. Then governments initiated the "Transition". Now, eating human meat - "special meat" - is legal. Marcos tries to stick to numbers, consignments, processing.

Once you get it, you simply cannot stop screaming. You can’t eat or sleep. It drives you more and more insane until you can’t stand to be alive a second longer. When the phenomenon hits Chuck's city, the chronically unemployed pervert joins a band of misfits to make his final stand.