Sasha has had it. She cannot bring herself to respond to another inane, “urgent” email or participate in the corporate employee joyfulness program. She hasn’t seen her friends in months. Sex? Seems like a lot of effort. Even cooking dinner takes far too much planning. Sasha has hit a wall. Armed with good intentions to drink kale smoothies, try yoga, and find peace, she heads to the seaside resort she loved as a child. But it’s the off season, the hotel is in a dilapidated shambles, and she has to share the beach with the only other occupant: a grumpy guy named Finn.

When her twenty-two-year-old stepdaughter announces her engagement to her pandemic boyfriend, Sarah Danhauser is shocked. But headstrong Ruby has already set a date (just three months away!) and spoken to her beloved safta, Sarah’s mother Veronica, about having the wedding at the family’s beach house in Cape Cod. Sarah might be worried, but Veronica is thrilled to be bringing the family together one last time before putting the big house on the market. But the road to a wedding day usually comes with a few bumps

Hollis Shaw, creator of the popular food blog, Hungry with Hollis, is shocked when her heart surgeon husband, Matthew, is killed in a one-car accident on a snowy morning. The cracks in Hollis’s perfect life—her strained marriage and her complicated relationship with her daughter, Caroline—grow deeper. So when Hollis hears about something called a “Five-Star Weekend”—one woman organizes a trip for her best friend from each phase of her life: her teenage years, her twenties, her thirties, and midlife—she decides to host her own Five-Star Weekend on Nantucket.

Daisy Shoemaker can’t sleep. With a thriving cooking business, full schedule of volunteer work, and a beautiful home in the Philadelphia suburbs, she should be content. But her teenage daughter can be a handful, her husband can be distant, her work can feel trivial, and she has lots of acquaintances, but no real friends. Still, Daisy knows she’s got it good. So why is she up all night?

Growing up in 1950s Detroit, they live in a perfect “Dick and Jane” house, where their roles in the family are clearly defined. Jo is the tomboy, the bookish rebel with a passion to make the world more fair; Bethie is the pretty, feminine good girl, a would-be star who enjoys the power her beauty confers and dreams of a traditional life. But the truth ends up looking different from what the girls imagined. Jo and Bethie survive traumas and tragedies.

In the spring of 2020, Lara’s three daughters return to the family's orchard in Northern Michigan. While picking cherries, they beg their mother to tell them the story of Peter Duke, a famous actor with whom she shared both a stage and a romance years before at a theater company called Tom Lake. As Lara recalls the past, her daughters examine their own lives and relationship with their mother, and are forced to reconsider the world and everything they thought they knew.

High-powered businesswoman Lana Rubicon has a lot to be proud of: her keen intelligence, impeccable taste, and the L.A. real estate empire she’s built. But when she finds herself trapped 300 miles north of the city, convalescing in a sleepy coastal town with her adult daughter Beth and teenage granddaughter Jack, Lana is stuck counting otters instead of square footage—and hoping that boredom won’t kill her before the cancer does.

Mia, the irreverent, hyperanalytical twenty-year-old daughter, has an explanation for everything—which is why she isn’t initially concerned when her father and younger brother Eugene don’t return from a walk in a nearby park. They must have lost their phone. Or stopped for an errand somewhere. But by the time Mia’s brother runs through the front door bloody and alone, it becomes clear that the father in this tight-knit family is missing and the only witness is Eugene, who has the rare genetic condition Angelman syndrome and cannot speak.

Celebrating her forty-fifth birthday at her local pub, popular podcaster Alix Summer crosses paths with an unassuming woman called Josie Fair. Josie, it turns out, is also celebrating her forty-fifth birthday. They are, in fact, birthday twins. A few days later, Alix and Josie bump into each other again, this time outside Alix’s children’s school. Josie has been listening to Alix’s podcasts and thinks she might be an interesting subject for her series. She is, she tells Alix, on the cusp of great changes in her life.

Claire has a problem with setting limits. All her life she has taken on every responsibility, assumed every burden, granted every request. Claire wants it all—and in the eyes of her friends, she has it: a devoted husband, four beautiful children, even a successful career as an artist. So when she agrees to chair the committee for Nantucket's social event of the year, she knows she can handle it. Claire can handle anything. But when planning the gala propels her into the orbit of billionaire Lock Dixon, unexpected sparks begin to fly.

Nisha Cantor lives the globetrotting life of the seriously wealthy, until her husband announces a divorce and cuts her off. Nisha is determined to hang onto her glamorous life. But in the meantime, she must scramble to cope--she doesn’t even have the shoes she was, until a moment ago, standing in. That’s because Sam Kemp—in the bleakest point of her life—has accidentally taken Nisha’s gym bag. But Sam hardly has time to worry about a lost gym bag—she’s struggling to keep herself and her family afloat.

When Tara Connelly is released from prison after serving eighteen months on a drug charge, she knows rebuilding her life at thirty years old won’t be easy. With no money and no prospects, she returns home to live with her siblings, who are both busy with their own problems. Her brother, a single dad, struggles with the ongoing effects of a brain injury he sustained years ago, and her sister’s fragile facade of calm and order is cracking under the burden of big secrets.

For Kate Klein, suburbia's been full of unpleasant surprises. Her once-loving husband is hardly ever home. The supermommies on the playground routinely snub her. Her days are spent carpooling, and at night, most of her orgasms are of the do-it-yourself variety. So when a fellow mother is murdered, Kate finds that the unsolved mystery is one of the most interesting things to happen in Upchurch. She launches an unofficial investigation with the help of two friends and discovers the secrets and lies behind the town's placid picket-fence facade....

Addie Downs and Valerie Adler will be best friends forever. That's what Addie believes after Valerie moves across the street when they're both nine years old. But in the wake of betrayal during their teenage years, Val is swept into the popular crowd, while mousy, sullen Addie becomes her school's scapegoat.

Harriet and Wyn have been the perfect couple since they met in college—they go together like salt and pepper, honey and tea, lobster and rolls. Except, now—for reasons they’re still not discussing—they don’t. They broke up five months ago. And still haven’t told their best friends. Which is how they find themselves sharing a bedroom at the Maine cottage that has been their friend group’s yearly getaway for the last decade.