In the opening pages of Jamie Ford's stunning debut, Hotel on the Corner of Bitter and Sweet, Henry Lee comes upon a crowd gathered outside the Panama Hotel, once the gateway to Seattle's Japantown. It has been boarded up for decades, but now the new owner has made an incredible discovery: the belongings of Japanese families, left when they were rounded up and sent to internment camps during World War II. As Henry looks on, the owner opens a Japanese parasol.

Eniola is tall for his age, a boy who looks like a man. Because his father has lost his job, Eniola spends his days running errands for the local tailor, collecting newspapers, begging when he must, dreaming of a big future. Wuraola is a golden girl, the perfect child of a wealthy family. Now an exhausted young doctor in her first year of practice, she is beloved by Kunle, the volatile son of an ascendant politician.

Funmi, Enitan, and Zainab first meet at university in Nigeria and become friends for life despite their differences. Funmi is beautiful, brash, and determined; Enitan is homely and eager, seeking escape from her single mother's smothering and needy love; Zainab is elegant and reserved, raised by her father's first two wives after her mother's death in childbirth. Their friendship is complicated but enduring, and over the course of the novel, the listener learns about their loves and losses.

It’s fair to say that Maddie’s life in London is far from rewarding. With a mother who spends most of her time in Ghana (yet still somehow manages to be overbearing), Maddie is the primary caretaker for her father, who suffers from advanced stage Parkinson’s. At work, her boss is a nightmare and Maddie is tired of always being the only Black person in every meeting.

Afi Tekple is a young seamstress in Ghana. She is smart; she is pretty; and she has been convinced by her mother to marry a man she does not know. Afi knows who he is, of course—Elikem is a wealthy businessman whose mother has chosen Afi in the hopes that she will distract him from his relationship with a woman his family claims is inappropriate. But Afi is not prepared for the shift her life takes when she is moved from her small hometown of Ho to live in Accra, Ghana’s gleaming capital, a place of wealth and sophistication where she has days of nothing to do but cook meals.