Ann Patchett’s award winning, New York Times best-selling Bel Canto balances themes of love and crisis as disparate characters learn that music is their only common language. As in Pratchett’s other novels, including Truth & Beauty and The Magician’s Assistant, the author’s lyrical prose and lucid imagination make Bel Canto a captivating story of strength and frailty, love and imprisonment, and an inspiring tale of transcendent romance.

St. Elizabeth's is a lovely old place in a small town in Kentucky that used to be the beautiful Hotel Louisa. In the 1960s, it is a home for unwed mothers run by nuns. Life at St. Elizabeth's is not unpleasant, but it is temporary. All the pregnant women who come there will go home within the year. Except for Rose, a beautiful, mysterious woman, who is neither unwed nor alone. She is simply pregnant and doesn't want her husband or her mother to know. She plans to give her baby up because she knows she cannot be the mother the baby needs.

Research scientist Dr. Marina Singh is sent to Brazil to track down her former mentor, Dr. Annick Swenson, who seems to have disappeared in the Amazon while working on an extremely valuable new drug. The last person who was sent to find her died before he could complete his mission. Plagued by trepidation, Marina embarks on an odyssey into the insect-infested jungle in hopes of finding answers to the questions about her friend's death, her company's future, and her own past.

It's a winter evening in Boston and the temperature has drastically dropped as a blizzard approaches the city. On this fateful night, Bernard Doyle plans to meet his two adopted sons, Tip the older, and more serious and Teddy, the affectionate dreamer, at a Harvard auditorium to hear a speech given by Jesse Jackson. Doyle, an Irish Catholic and former Boston mayor, has done his best to keep his two sons interested in politics, from the day he and his now deceased wife became their parents, through their childhoods, and now in their lives as college students.

One Sunday afternoon in Southern California, Bert Cousins shows up at Franny Keating's christening party uninvited. Before evening falls, he has kissed Franny's mother, Beverly - thus setting in motion the dissolution of their marriages and the joining of two families.