Detective Kara Quinn, on leave from the LAPD, is on an early morning jog in her hometown of Liberty Lake when she comes upon the body of a young nurse. The manner of death shows a pattern of highly controlled rage. Meanwhile in DC, FBI Special Agent Mathias Costa is staffing his newly minted Mobile Response Team. Word reaches Matt that the Liberty Lake murder fits the profile of the compulsive Triple Killer. It will be the first case for the MRT. This time, they have a chance to stop this zealous, if elusive, killer before he strikes again.

Lucas Vega is obsessed with the death of Candace Swain, who left a sorority party one night and never came back. Her body was found after two weeks, but the case has grown cold. Three years later while interning at the medical examiner's, Lucas discovers new information, but the police are not interested.

Working alone as a private investigator is tough. Estranged from her PI family, Margo Angelhart does what she must to get by—including taking on sordid cases that pay the bills, even if she’d rather be helping those the justice system has failed. That is, until a cheating husband case she’s working intersects with her siblings’ corporate espionage investigation, forcing Margo to cooperate with the Angelhart firm. Now, as the siblings compare notes, it’s clear they need to work together before a white-collar crime escalates to murder.

When a man is shot in the head, Bree Taggert and her new partner, veteran detective Dana Romano, respond to the call. They break the news to the victim’s ex-wife and learn the estranged couple’s five-year-old daughter was supposed to have been with him. What starts as a murder investigation quickly morphs into a desperate search for a missing child. The case stirs memories of Bree’s own traumatizing childhood. To find the little girl, Bree will have to relive her own terrifying past.

Recently engaged and deeply ensconced in her third year of surgical residency in Chicago, Emily Hartford gets a shock when she is called home to Freeport, Michigan, the small town she fled a decade ago after the death of her mother. Her estranged father, the local medical examiner, has had a massive heart attack. At the hospital, she finds her father in near total denial of the seriousness of his condition. He insists that the best thing Emily can do to help him is to take on the autopsy of a senator's teen daughter whose sudden, unexplained death has just rocked the sleepy town.