Single mom Jess Davis is a data and statistics wizard, but no amount of number crunching can convince her to step back into the dating world. After all, her father was never around, her hard-partying mother disappeared when she was six, and her ex decided he wasn’t “father material” before her daughter was even born. Jess holds her loved ones close but working constantly to stay afloat is hard...and lonely. But then Jess hears about GeneticAlly, a buzzy new DNA-based matchmaking company that’s predicted to change dating forever.

The many lives of theoretical physicist Elsie Hannaway have finally caught up with her. By day, she’s an adjunct professor, toiling away at grading labs and teaching thermodynamics in the hopes of landing tenure. By other day, Elsie makes up for her non-existent paycheck by offering her services as a fake girlfriend, tapping into her expertly honed people-pleasing skills to embody whichever version of herself the client needs. Honestly, it’s a pretty sweet gig—until her carefully constructed Elsie-verse comes crashing down.

Olive Torres is used to being the unlucky twin: from inexplicable mishaps to a recent layoff, her life seems to be almost comically jinxed. By contrast, her sister Ami is an eternal champion...she even managed to finance her entire wedding by winning a slew of contests. Unfortunately for Olive, the only thing worse than constant bad luck is having to spend the wedding day with the best man (and her nemesis), Ethan Thomas.

Harriet and Wyn have been the perfect couple since they met in college—they go together like salt and pepper, honey and tea, lobster and rolls. Except, now—for reasons they’re still not discussing—they don’t. They broke up five months ago. And still haven’t told their best friends. Which is how they find themselves sharing a bedroom at the Maine cottage that has been their friend group’s yearly getaway for the last decade.

After a wild bet, gourmet grilled-cheese sandwich, and cuddle with a baby goat, Alexis Montgomery has had her world turned upside down. The cause: Daniel Grant, a ridiculously hot carpenter who’s ten years younger than her and as casual as they come—the complete opposite of sophisticated city-girl Alexis. And yet their chemistry is undeniable.

Sadie Montgomery never saw what was coming . . . Literally! One minute she’s celebrating the biggest achievement of her life—placing as a finalist in the North American Portrait Society competition—the next she’s lying in a hospital bed diagnosed with a “probably temporary” condition known as face blindness. She can see, but every face she looks at is now a jumbled puzzle of disconnected features. Imagine trying to read a book upside down and in another language. This is Sadie’s new reality.

Hallie Welch fell hard for Julian Vos at fourteen, after they almost kissed in the dark vineyards of his family’s winery. Now the prodigal hottie has returned to Napa Valley, and when Hallie is hired to revamp the gardens on the Vos estate, she wonders if she'll finally get that smooch. But the starchy professor isn’t the teenager she remembers and their polar opposite personalities clash spectacularly. One wine-fueled girls’ night later, Hallie can’t shake the sense that she did something reckless.

Growing up the daughter of notorious treasure hunter and absentee father Duke Wilder left Lily without much patience for the profession…or much money in the bank. But Lily is resourceful, and now uses Duke’s coveted hand-drawn maps to guide tourists on fake treasure hunts through the red rock canyons of Utah. It pays the bills but doesn’t leave enough to fulfill her dream of buying back the beloved ranch her father sold years ago, and definitely not enough to deal with the sight of the man she once loved walking back into her life with a motley crew of friends ready to hit the trails.

Amelia Rose, known as Rae Rose to her adoring fans, is burned-out from years of maintaining her “princess of pop” image. Inspired by her favorite Audrey Hepburn film, Roman Holiday, she drives off in the middle of the night for a break in Rome . . . Rome, Kentucky, that is. When Noah Walker finds Amelia on his front lawn in her broken-down car, he makes it clear he doesn’t have the time or patience for celebrity problems. He’s too busy running the pie shop his grandmother left him and reminding his nosy but lovable neighbors to mind their own damn business.

Carey Duncan has worked for home remodeling and design gurus Melissa and Rusty Tripp for nearly a decade. A country girl at heart, Carey started in their first store at 16, and - more than anyone would suspect - has helped them build an empire. With a new show and a book about to launch, the Tripps are on the verge of superstardom. There’s only one problem: America’s favorite couple can’t stand each other.

Hallie Piper is turning over a new leaf. After belly-crawling out of a hotel room (hello, rock bottom), she decides it’s time to become a full-on adult. She gets a new apartment, a new haircut, and a new wardrobe, but when she logs onto the dating app that she has determined will find her new love, she sees none other than Jack, the guy whose room she snuck out of.

Prepared for a good time, Tessa is thrilled to spend the weeks before her sister’s wedding at their family’s favorite vacation spot: Santorini. Sandy beaches, stonewashed houses, attractive men—it’s heaven. But Tessa’s idea of a girls’ trip comes to a screaming halt when her sister thinks it’s high time Tessa finds some love herself. Unfortunately, Tessa forgot about the deal she made back in high school: she has to find her soulmate before her sister’s wedding. Or else.

Hannah Brooks looks more like a kindergarten teacher than somebody who could kill you with a wine bottle opener. Or a ballpoint pen. Or a dinner napkin. But the truth is, she’s an Executive Protection Agent (aka "bodyguard"), and she just got hired to protect superstar actor Jack Stapleton from his middle-aged, corgi-breeding stalker.

Rescued by Calvin McLoughlin from a would-be subway attacker, Holland Bakker pays the brilliant musician back by pulling some of her errand-girl strings and getting him an audition with a big-time musical director. When the tryout goes better than even Holland could have imagined, Calvin is set for a great entry into Broadway - until he admits his student visa has expired and he's in the country illegally. Holland impulsively offers to wed the Irishman to keep him in New York, her growing infatuation a secret only to him.

Kitty Hart has become internet famous as the Kitty Whisperer for her expertise on all things feline, and as a result, her cat-sitting business is booming. But lately, she has a terrible feeling that maybe her life isn’t quite going where it’s supposed to—especially after falling face-first into her newest client. Not exactly the best first impression. Fortunately, Miles Thorn is just as bad at first impressions. Strike one: he doesn’t like cats, especially Prince Francis, the haughty and mischievous Sphynx his mom left in his care.