After too many dates, thirtysomething Mimi Perkins is still single, unmoored, and longing for love. So when Ren Yardley—a handsome, divorced fellow drama teacher and single father—falls in love with her and proposes, she’s sure this is at last the good news her psychic predicted. Soon after proposing, Ren receives the devastating news that his ex-wife has been in a debilitating car accident, prompting him to temporarily move back into his former home to care for her and his daughters.

After being together for 10 years, Sylvie and Dan have all the trimmings of a happy life and marriage; they have a comfortable home, fulfilling jobs, and beautiful twin girls and communicate so seamlessly, they finish each other's sentences. However, a trip to the doctor projects they will live another 68 years together, and panic sets in. They never expected "until death do us part" to mean seven decades. In the name of marriage survival, they quickly concoct a plan to keep their relationship fresh and exciting.

Charlotte "Charlie" Silver has always been a good girl. She excelled at tennis early, coached by her father, a former player himself, and soon became one of the top juniors in the world. When she leaves UCLA - and breaks her boyfriend's heart - to turn pro, Charlie joins the world's best athletes, who travel 11 months a year, competing without mercy for Grand Slam titles and Page Six headlines.

A producer at the BBC and mother to a new baby, Tessa is at work in Belfast one day when the news of another raid comes on the air. The IRA may have gone underground in the two decades since the Good Friday Agreement, but they never really went away, and lately bomb threats, security checkpoints, and helicopters floating ominously over the city have become features of everyday life. As the news reporter requests the public's help in locating those responsible for the robbery, security footage reveals Tessa's sister, Marian, pulling a black ski mask over her face.

Andrea Sachs, a small-town girl fresh out of college, is hired as the assistant to Miranda Priestly, the successful editor of Runway magazine. Andrea finds herself in an office that shouts Prada! Armani! Versace! at every turn. As things escalate from the merely unacceptable to the downright outrageous, Andrea begins to realize that the job a million girls would die for may just kill her. And even if she survives, she has to decide whether the job is worth the price of her soul.

Jen Weinstein and Lauren Parker rule the town of Salcombe, Fire Island every summer. They hold sway on the beach and the tennis court, and are adept at manipulating people to get what they want. Their husbands, Sam and Jason, have summered together on the island since childhood, despite lifelong grudges and numerous secrets. Their one single friend, Rachel Woolf, is looking to meet her match, whether he’s the tennis pro. But even with plenty to gossip about, this season starts out as quietly as any other. Until a body is discovered, face down, off the side of the boardwalk.

Hot-shot lawyer McKenna Keaton finds herself in hot water with her own law firm when she’s (falsely!) accused of embezzlement. Placed on unpaid leave, she suddenly finds herself with the free time to return home and attend her youngest sister’s wedding activities. But it’s not all fun and games. Waiting back home is shy, nerdy Henry Blumenthal—McKenna’s high school rival for valedictorian who once took three hours to beat her at chess. Scratch that. He’s Hank Blume now, the famed documentarian, Durham, North Carolina’s, darling son.

Sasha has had it. She cannot bring herself to respond to another inane, “urgent” email or participate in the corporate employee joyfulness program. She hasn’t seen her friends in months. Sex? Seems like a lot of effort. Even cooking dinner takes far too much planning. Sasha has hit a wall. Armed with good intentions to drink kale smoothies, try yoga, and find peace, she heads to the seaside resort she loved as a child. But it’s the off season, the hotel is in a dilapidated shambles, and she has to share the beach with the only other occupant: a grumpy guy named Finn.

When 27-year-old Bette Robinson quits her Manhattan banking job, she knows she won't miss the 80-hour workweeks, her claustrophobic cubicle or her revolting boss's Quotes of the Day. Then Bette meets Kelly, head of Manhattan's hottest PR and events planning firm, and suddenly she has a brand-new job where the primary requirement is to see and be seen. The work at Kelly & Company takes Bette inside the VIP rooms of the city's most exclusive nightclubs, to parties crowded with celebrities and socialites.

Leigh, Adriana and Emmy are best friends, all leading different lives and about to make some extreme choices. The three girls meet for dinner one evening and make a pact - they each have to change one thing in their lives by the end of the year.