Crippled by lupus at 25, celebrated author Flannery O'Connor was forced to leave New York City and return home to Andalusia, her family farm in Milledgeville, Georgia. Years later, as Flannery is finishing a novel and tending to her menagerie of peacocks, her mother drags her to the wedding of a family friend....

Julia Ames, after a youth marked by upheaval and emotional turbulence, has found herself on the placid plateau of mid-life. But Julia has never navigated the world with the equanimity of her current privileged class. Having nearly derailed herself several times, making desperate bids for the kind of connection that always felt inaccessible to her, she finally feels, at age fifty seven, that she has a firm handle on things. She’s unprepared, though, for what comes next.

In this “rich, complex family saga” (USA Today) full of long-buried family secrets, Marilyn Connolly and David Sorenson fall in love in the 1970s, blithely ignorant of all that awaits them. By 2016, they have four radically different daughters, each in a state of unrest.

One summer morning, twelve-year-old Edward Adler, his beloved older brother, his parents, and 183 other passengers board a flight in Newark headed for Los Angeles. Among them are a Wall Street wunderkind, a young woman coming to terms with an unexpected pregnancy, an injured veteran returning from Afghanistan, a business tycoon, and a free-spirited woman running away from her controlling husband. Halfway across the country, the plane crashes. Edward is the sole survivor.

William Waters grew up in a house silenced by tragedy, where his parents could hardly bear to look at him, much less love him—so when he meets the spirited and ambitious Julia Padavano in his freshman year of college, it’s as if the world has lit up around him. With Julia comes her family, as she and her three sisters are inseparable: Sylvie, the family’s dreamer, is happiest with her nose in a book; Cecelia is a free-spirited artist; and Emeline patiently takes care of them all.

Sam and Elena dream of another life. On the island off the coast of Washington where they were born and raised, they and their mother struggle to survive. Sam works on the ferry that delivers wealthy mainlanders to their vacation homes while Elena bartends at the local golf club, but even together they can’t earn enough to get by, stirring their frustration about the limits that shape their existence.

In 1950s Tehran, seven-year-old Ellie lives in grand comfort until the untimely death of her father, forcing Ellie and her mother to move to a tiny home downtown. Lonely and bearing the brunt of her mother’s endless grievances, Ellie dreams of a friend to alleviate her isolation. Luckily, on the first day of school, she meets Homa, a kind, passionate girl with a brave and irrepressible spirit. Together, the two girls play games, learn to cook in the stone kitchen of Homa’s warm home, wander through the colorful stalls of the Grand Bazaar, and share their ambitions for becoming “lion women.”

At birth, Violet and Rose Flowers were identical, save for a tiny bluish-purple mark gracing Violet’s slender neck. By nineteen, their temperaments distinguish them, as different as the flowers their mother named them for—Violet, wild and outgoing, and Rose, solitary and reserved. Still, they are each other’s world. Then, on a sweltering, terrible August night in 1928, an explosion rocks Lamb’s Dance Hall in Possum Flats, Missouri, engulfing it in flames, leaving one twin among the dozens dead, and her sister’s life forever changed.

At times stern, at other times patient, at times perceptive, at other times in sad denial, Olive Kitteridge, a retired schoolteacher, deplores the changes in her little town of Crosby, Maine, and in the world at large, but she doesn’t always recognize the changes in those around her: a lounge musician haunted by a past romance; a former student who has lost the will to live; Olive’s own adult child, who feels tyrannized by her irrational sensitivities; and her husband, Henry, who finds his loyalty to his marriage both a blessing and a curse.

With her remarkable insight into the human condition and silences that contain multitudes, Elizabeth Strout returns to the town of Crosby, Maine, and to her beloved cast of characters—Lucy Barton, Olive Kitteridge, Bob Burgess, and more—as they deal with a shocking crime in their midst, fall in love and yet choose to be apart, and grapple with the question, as Lucy Barton puts it, “What does anyone’s life mean?”

For the past two decades, Rocky has looked forward to her family’s yearly escape to Cape Cod. Their humble beach-town rental has been the site of sweet memories, sunny days, great meals, and messes of all kinds. This year’s vacation, with Rocky sandwiched between her half-grown kids and fully aging parents, promises to be just as delightful as summers past—except, perhaps, for Rocky’s hormonal bouts of rage and melancholy. Her body is changing—her life is, too. And then a chain of events sends Rocky into the past, reliving both the tenderness and sorrow of a handful of long-ago summers.

It's 1924 in Branchville, South Carolina, and three women have come to a crossroads. Gertrude, a mother of four, must make an unconscionable decision to save her daughters. Retta, a first-generation freed slave, comes to Gertrude's aid by watching her children, despite the gossip it causes in her community. Annie, the matriarch of the influential Coles family, offers Gertrude employment at her sewing circle, while facing problems of her own at home.

The year is 1921. Lesley Hamlyn and her husband, Robert, a lawyer and war veteran, are living at Cassowary House on the Straits Settlement of Penang. When “Willie” Somerset Maugham, a famed writer and old friend of Robert’s, arrives for an extended visit with his secretary Gerald, the pair threatens a rift that could alter more lives than one. Maugham, one of the great novelists of his day, is beleaguered: Having long hidden his homosexuality, his unhappy and expensive marriage of convenience becomes unbearable after he loses his savings—and the freedom to travel with Gerald.

“Any story that starts will also end.” As a writer, Ann Patchett knows what the outcome of her fiction will be. Life, however, often takes turns we do not see coming. Patchett ponders this truth in these wise essays that afford a fresh and intimate look into her mind and heart.

Natural-born healer Emma Starling once had big plans for her life, but she’s lost her way. A medical school dropout, she’s come back to small-town Everton, New Hampshire, to care for her father, who is dying from a mysterious brain disease. Clive Starling has been hallucinating small animals, as well as having visions of the ghost of a long-dead naturalist, Ernest Harold Baynes, once known for letting wild animals live in his house. This ghost has been giving Clive some ideas on how to spend his final days.