Since its inception in 2003, PEPFAR has transformed the landscape of HIV treatment and prevention. It is estimated that this program, which works to accelerate progress toward achieving HIV and AIDS epidemic control in over 50 countries globally, has saved over 20 million lives, prevented transmission to 5.5 million babies, and enabled countries to surpass UNAIDS’ 90-90-90 treatment targets. PEPFAR has also played a vital role in addressing other global health challenges, such as the COVID-19 pandemic, expanding care to marginalized groups such as adolescent girls and young women, key populations, pregnant people, children, and displaced persons.
PEPFAR released its new five-year strategy in December 2022, which sets bold priorities in the effort to eliminate HIV and AIDS as a public health threat by 2030. Advocates globally seek to ensure that more global health sectors are included in PEPFAR’s mission to provide integrated services, and that PEPFAR programming is inclusive of all people.