Welcome to the March 2025 episode of DiabetesBio—the American Diabetes Association’s podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the March 2025 issue of Diabetes.

3:20 In the first interview segment, our hosts discuss the Paper of the Month, “Resolving Spatiotemporal Electrical Signaling Within the Islet via CMOS Microelectrode Arrays.” They’re joined by Anne Gresch, PhD, a postdoctoral fellow at the University of Colorado’s Anschutz Medical Campus, and Prof. Dr. Martina Düfer, from the Department of Pharmacology at the University of Munster Pharmaceutical and Medicinal Chemistry in Munster, Germany. This article is available for free at doi.org/10.2337/db23-0870.

22:40 Our hosts discuss an article from the February issue of Diabetes, entitled “Genetics of C-Peptide and Age at Diagnosis in Type 1 Diabetes.” They’re joined by lead author Delnaz Roshandel, PhD, Senior Research Associate, and Andrew Paterson, MD, both of the Genetics and Genome Biology Program at the Hospital for Sick Children in Toronto, Canada. This article is available for free at doi.org/10.2337/db24-0340.

36:20 In the special edition of “Sweet Talk,” our hosts welcome Jeffrey S Flier, MD, former Dean of Harvard Medical School and past recipient of the ADA’s Banting Medal, as well as Christopher Bang Newgard, PhD, leader in pancreatic islet biology and metabolic disease at Duke University School of Medicine and previous recipient of the ADA’s Outstanding Scientific Achievement Award. They discuss an article by Diabetes editor-in-chief, David A. D’Alessio, on the historic development of the insulin radioimmunoassay, available for free at doi.org/10.2337/dbi24-0055.

To learn more about Diabetes and DiabetesBio, please visit diabetesjournals.org/diabetes. Thank you for listening, and don’t forget to smash that “follow” button!

Welcome to the February 2025 episode of DiabetesBio—the American Diabetes Association’s podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the February 2025 issue of Diabetes.

3:55 In the first interview segment, our hosts our joined by Francis C. Lynn, BSc PhD, Associate Professor in the Department of Surgery and School of Biomedical Engineering at the University of British Columbia in Vancouver. He is the corresponding author of the article “Tracking Insulin- and Glucagon-Expressing Cells In Vitro and In Vivo Using a Double-Reporter Human Embryonic Stem Cell Line.” The article is available for free at doi.org/10.2337/db24-0756.

18:25 Darleen, Kevin, and Kirk speak with David C. Wraith, PhD, Emeritus Professor of Immunology, and Michael J. Price, PhD, a research fellow, both at the Institute of Immunology and Immunotherapy at the University of Birmingham in the UK. They discuss their article, “Pre-clinical development of a tolerogenic peptide from glutamate decarboxylase as a candidate for antigen-specific immunotherapy in type 1 diabetes,” available at doi.org/10.2337/db23-0996.

35:50 In the latest edition of “Sweet Talk,” our hosts welcome Bret H. Goodpaster, PhD, Scientific Director and Senior Investigator at the AdventHealth Translational Research Institute for Metabolism and Diabetes in Orlando, FL, and Professor of Medicine at Johns Hopkins University.

To learn more about Diabetes and DiabetesBio, please visit diabetesjournals.org/diabetes. Thank you for listening, and don’t forget to smash that “follow” button!

Welcome to the January 2025 episode of DiabetesBio—the American Diabetes Association’s podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the January 2025 issue of Diabetes.

2:00 In a special format for the first episode of the new year, our hosts introduce a Sweet Talk double feature.

3:35 In part one of this special Sweet Talk segment, our hosts are joined by Philipp Scherer, PhD, Professor in the Department of Internal Medicine at the University of Texas Southwestern Medical Center in Dallas, Texas, and Director of the Touchstone Diabetes Center, and Joel Elmquist, DVM, PhD, Professor of Internal Medicine at UT Southwestern Medical Center, and Director of its Center for Hypothalamic Research. Both are previous recipients of the ADA’s Outstanding Scientific Achievement Award, and Scherer recently received the ADA’s Banting Medal.

They share their perspectives on the evolution of diabetes, obesity research, the interplay between the brain and adipose tissue, and what the future holds for understanding and treating these complex diseases.

33:00 In part two, our hosts speak with Jonathan Flak, PhD, Assistant Professor of Pharmacology & Toxicology at the Indiana University School of Medicine, and former recipient of the ADA’s Pathway to Stop Diabetes Award. He discusses his work on the brain’s role in glucose regulation, energy balance, and bodyweight control.

His article, “Functionally Separate Populations of Ventromedial Hypothalamic Neurons in Obesity and Diabetes: A Report on Research Supported by Pathway to Stop Diabetes,” can be found in the January 2025 issue of Diabetes.

To learn more about Diabetes and DiabetesBio, please visit diabetesjournals.org/diabetes. Thank you for listening, and don’t forget to smash that “follow” button!