This segment focuses on comprehensive and trauma-informed services in care and school settings. It defines the phrase “trauma-informed” and what this means in the context of teachers and other caregivers working with young children. It also discusses the positive impacts trauma-informed approaches can have on children, and how these impacts and other protective factors play a role in reducing the risk of Indigenous girls and boys becoming murdered or missing. Other topics include what more is needed to bring these practices and approaches to Head Start, childcare, and other programs and practitioners serving young children throughout Indigenous communities. The featured guests are Dr. Amy Wolferman, Director, School-Based Training and Technical Assistance at the National Native Children’s Trauma Center (NNCTC) and Kimee Wind Hummingbird (Muscogee Creek) Nation with Cherokee Descent), Training and Technical Assistance Specialist at NNCTC.