This episode explores the relationship between mental fatigue and reaction time. It defines mental fatigue, discusses its causes and effects on performance, and examines various methods for measuring it, particularly using the BrainSherpa - Psychomotor Vigilance Test (PVT). The text highlights the impact of mental fatigue on reaction time, exploring mitigation strategies such as breaks, environmental adjustments, and training programs. Finally, it underscores the importance of understanding and addressing mental fatigue to improve performance and safety, especially in demanding professions.