Probably not. But Wall Street Journal reporter Jeff Horwitz decided to try anyway, putting his body — and specifically his butt — on the line to answer a seemingly straightforward question: Is it possible to build up a tolerance to poison oak by eating it? Guest: Jeff Horwitz, reporter at the Wall Street Journal; and Mahmoud ElSohly, professor of pharmaceutics at the University of Mississippi For show transcripts, go to vox.com/unxtranscripts For more, go to vox.com/unexplainable And please email us! unexplainable@vox.com We read every email. Support Unexplainable by becoming a Vox Member today: vox.com/members Learn more about your ad choices. Visit podcastchoices.com/adchoices