Sounds of Science

Written by: Charles River
  • Summary

  • Sounds of Science is a monthly podcast about beginnings: how a molecule becomes a drug, how a rodent elucidates a disease pathway, how a horseshoe crab morphs into an infection fighter. The podcast is produced by Eureka, the scientific blog of Charles River, a contract research organization for drug discovery and development. Tune in and begin the journey.
    © 2025 Charles River
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Episodes
  • Ep. 89: Rethinking Toxicology: The Future of NAMs in Agrochemicals
    Mar 4 2025

    The agrochemical field has long relied on animal models to evaluate the safety and efficacy of substances, but there’s a growing demand to adopt new alternative methods (NAMs) that can further the industry while reducing the need for animal testing. However, questions remain as to their long-term viability.


    Join Robert Landsiedel, Vice President of Experimental Toxicology and Ecology, and Susanne Kolle, Research Coordinator of Experimental Toxicology and Ecology at BASF, as they explain the benefits of NAMs, how they comply with the 3Rs principle, and the role collaboration is playing to push NAMs as a viable alternative to animals.

    Show Notes

    Alternative Methods

    AMAP Strategic Partnerships

    Animals in Research

    Modernizing Drug Development

    Agrochemical Testing Service for Approvals

    Chemical Testing Services

    Charles River Laboratories Announces Development of Nonclinical Virtual Control Groups with Sanofi to Reduce the Use of Animals

    Charles River Laboratories, in Collaboration with MatTek Corporation, Awarded Grant from the Foundation for Chemistry Research and Initiatives to Advance Research Alternatives

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    28 mins
  • Ep. 88: The Epidemiology of Cancer
    Feb 18 2025

    How can genetic, geographic, and social considerations effect outcomes for Black women with cancer? To answer this question, I am joined this week by Dr. Lauren E. McCullough, Associate Professor in the Department of Epidemiology at the Rollins School of Public Health, and Julia Schueler, Research Director Therapeutic Area Lead Oncology for Charles River. Dr. McCullough is also one of the lead researchers for the American Cancer Society’s VOICES of Black Women initiative, which will track the health of participants over several years to gain insight into health considerations for Black women. For more information on how to enroll, please visit voices.cancer.org.

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    31 mins
  • Ep. 87: Taking a Customized and Collaborative Approach to Therapeutic Development
    Feb 4 2025

    The N=1 Collaborative is changing the way we view drug development. Their specialty is creating customized therapies tailored to individual patients, paving the way for a unique approach that can leave long-lasting impacts on those with ultra-rare diseases.

    Join us as Executive Director Hugh Hempel discusses the origins of N=1, the collaborative effort it takes to advance customized therapies down the pipeline, and what the future holds for the field of individualized medicine.

    Show Notes

    n=1 Collaborative

    Rare Disease | Charles River

    Rare Disease Research for Drug Development

    Repurposing Drugs for Rare Disease

    S4 E07: Free For Life: The Story of N-Lorem Foundation

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    29 mins

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