Episodes

  • Ep. 95: “Lymphocyte Signaling” Featuring Dr. Gail Bishop

    Ep. 95: “Lymphocyte Signaling” Featuring Dr. Gail Bishop
    Dec 17 2024
    Dr. Gail Bishop is a Professor of Microbiology and Immunology at the University of Iowa, where her lab studies the molecular mechanisms underlying lymphocyte activation and tolerance. She talks about TRAF signaling, the NFκB pathway, and effects on B and T lymphocytes. She also discusses her role as Editor-in-Chief of The Journal of Immunology.
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    1 hr and 12 mins
  • Ep. 94: “Engineering Immunity” Featuring Dr. Lili Yang

    Ep. 94: “Engineering Immunity” Featuring Dr. Lili Yang
    Dec 3 2024
    Dr. Lili Yang is a Professor of Microbiology, Immunology, and Molecular Genetics at the University of California, Los Angeles. Her research centers on deciphering the molecular mechanisms regulating anti-cancer immune responses, exploiting knowledge to develop novel immunotherapies for treating cancer, and translating these new cancer immunotherapies from bench to bedside. She talks about engineering off-the-shelf immunotherapies to fight cancer and generating CAR-NKT cells from hematopoietic stem and progenitor cells. She also discusses the role of serotonin and how SSRIs can affect cancer therapy efficacy.
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    1 hr and 20 mins
  • Ep. 93: “Cancer Immune Regulation” Featuring Dr. Rahul Roychoudhuri

    Ep. 93: “Cancer Immune Regulation” Featuring Dr. Rahul Roychoudhuri
    Nov 19 2024
    Dr. Rahul Roychoudhuri is a Professor of Cancer Immunology at the University of Cambridge (Department of Pathology) and Director (Non-Clinical) of the CRUK Cambridge Centre Training Programme. His lab studies immunoregulatory mechanisms in inflammation and cancer. He talks about enhancing cell therapy with new payloads and targeting cancer cells during metastasis.
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    1 hr and 2 mins
  • Ep. 92: “Cell Death and Immunity” Featuring Dr. Pascal Meier

    Ep. 92: “Cell Death and Immunity” Featuring Dr. Pascal Meier
    Nov 5 2024
    Dr. Pascal Meier is a Professor and Group Leader at the Institute of Cancer Research in London, England. His group investigates the complex relationship between cell death, immunity, and tumorigenesis. Particularly, they are focused on the role of cell death and inflammation in adaptation to tissue stress, treatment resistance, and tumour surveillance.
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    1 hr and 16 mins
  • Ep. 91: “Immune Regulation and Inflammation” Featuring Dr. Marcelo Hill

    Ep. 91: “Immune Regulation and Inflammation” Featuring Dr. Marcelo Hill
    Oct 29 2024
    Dr. Marcelo Hill is the Head of the Laboratory of Immunoregulation and Inflammation at the Institut Pasteur de Montevideo. He is also the Founder and Chief Scientific Officer of ARDAN ImmunoPharma. His research focuses on immune regulation in cancer, and how T cells respond to immunotherapy in melanoma. He talks about improving immunotherapy efficacy by activating the inflammasome, and how he is pushing this research towards the clinic by collaborating with industry and creating a spin-off company. He is then joined by Drs. Marion Brunck and María Julia Lamberti, who discuss the upcoming meeting of the Latin American and Caribbean Association of Immunology, taking place November 4-8 in Buenos Aires. They discuss the challenges and opportunities in the Latin American immunology community, and how this conference aims to promote collaborations and empower early-career researchers.
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    1 hr and 12 mins
  • Ep. 90: “Explaining Immunology” Featuring Drs. JoAnne Flynn and Stephen Hedrick

    Ep. 90: “Explaining Immunology” Featuring Drs. JoAnne Flynn and Stephen Hedrick
    Oct 22 2024
    Dr. JoAnne Flynn is a Professor of Microbiology and Molecular Genetics at the University of Pittsburgh and Dr. Stephen Hedrick is Chancellor's Associates Chair VII Distinguished Professor Emeritus at the University of California, San Diego. They talk about the American Association of Immunologists' Immunology Explained campaign, which aims to explain the science of the immune system to the general public. They also discuss their efforts to educate legislators about the value of immunology research and promoting childhood vaccination.
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    1 hr and 26 mins
  • Ep. 89: “Host-Microbiota Interactions” Featuring Dr. Theresa Alenghat

    Ep. 89: “Host-Microbiota Interactions” Featuring Dr. Theresa Alenghat
    Oct 8 2024
    Dr. Theresa Alenghat is a Professor in the Immunobiology Division and the Margaret K. Hostetter Chair at Cincinnati Children’s Hospital Medical Center, University of Cincinnati. Her lab investigates mechanisms underlying the host-microbiota relationship, and how this regulation affects intestinal immunity and inflammatory bowel disease. She discusses how butyrate affects tuft cells in the intestine.
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    1 hr and 9 mins
  • Ep. 88: “Cancer and Inflammatory Diseases” Featuring Dr. Roslyn Kemp

    Ep. 88: “Cancer and Inflammatory Diseases” Featuring Dr. Roslyn Kemp
    Sep 24 2024
    Dr. Roslyn Kemp is a Professor of Immunology at the University of Otago. Her research focuses on T cells as mediators of anti-tumor immunity and inflammation. She discusses using organoids to model inflammatory bowel disease and collecting immune cell signatures in cancer. She also talks about writing a book to demystify science research and careers.
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    59 mins