History Medicine Science

ADHD may be the defining diagnosis of our time. According to the latest data, more than 10 percent of American children (that’s 7.1 million kids) have been diagnosed with ADHD. And the number of stimulant prescriptions for adults in their 30s has shot up nearly threefold since 2012. In recent years, this explosion in demand has combined with other factors to create a widespread stimulant shortage in the US. In the second installment of Backfired, cohosts Leon Neyfakh and Arielle Pardes look at the unintended consequences of the ADHD industry, and trace the surprising path that brought us here.

While many Westerners still think of yoga as an invigorating series of postures and breathing exercises, these physical practices are only part of a vast and ancient spiritual science. For more than three millennia, yoga sages systematically explored the essential questions of our human existence: What are the root causes of suffering, and how can we achieve freedom and happiness? What would it be like to function at the maximum potential of our minds, bodies, and spirits? What is an optimal human life?

With eloquent simplicity, one of the world's last Native American medicine men demonstrates how traditional tribal wisdom can help us maintain spiritual and physical health in today's world.

Interweaving a grand historical narrative with cutting-edge climate science and genetic discoveries, Kyle Harper traces how the fate of Rome was decided not just by emperors, soldiers, and barbarians but also by volcanic eruptions, solar cycles, climate instability, and devastating viruses and bacteria. He takes listeners from Rome's pinnacle in the second century, when the empire seemed an invincible superpower, to its unraveling by the seventh century, when Rome was politically fragmented and materially depleted.

Written by an author with plenty of experience holding a scalpel, Dr. David Schneider's in-depth biography is an encompassing history of the practice that has leapt forward over the centuries from the dangerous guesswork of ancient Greek physicians through the world-changing implant revolution of the 20th century.

The 1964 murder of a nationally known cancer researcher sets the stage for this gripping exposé of medical professionals enmeshed in covert government operations over the course of three decades. Following a trail of police records, FBI files, cancer statistics, and medical journals, this revealing book presents evidence of a web of medical secret-keeping that began with the handling of evidence in the JFK assassination and continued apace....

Mescaline, LSD, and psilocybin mushrooms. There’s been a lot of discussion in the medical world lately about the potential benefits of these and other drugs for certain medical conditions, such as anxiety and depression. As we consider the place of psychedelics in the future, we can draw insight and guidance from the history of how psychedelics have been described, sought after, applied, and prohibited over the centuries. Erika Dyck, professor of history at the University of Saskatchewan, introduces you to the world of hallucinogens.

Tuberculosis has been entwined with humanity for millennia. Once romanticized as a malady of poets, today tuberculosis is a disease of poverty that walks the trails of injustice and inequity we blazed for it. In 2019, John Green met Henry, a young tuberculosis patient at Lakka Government Hospital in Sierra Leone while traveling with Partners in Health. John became fast friends with Henry, a boy with spindly legs and a big, goofy smile. In the years since that first visit to Lakka, Green has become a vocal and dynamic advocate for increased access to treatment.

Despite advances in health care, infectious microbes continue to be a formidable adversary to scientists and doctors. Vaccines and antibiotics, the mainstays of modern medicine, have not been able to conquer infectious microbes because of their amazing ability to adapt, evolve, and spread to new places. Terrorism aside, one of the greatest dangers from infectious disease we face today is from a massive outbreak of drug-resistant microbes.

The Emperor of All Maladies reveals the many faces of an iconic, shape-shifting disease that is the defining plague of our generation. The story of cancer is a story of human ingenuity, resilience, and perseverance but also of hubris, arrogance, paternalism, and misperception, all leveraged against a disease that, just three decades ago, was thought to be easily vanquished in an all-out "war against cancer".

A definitive history of mescaline that explores its mind-altering effects across cultures, from ancient America to Western modernity. Mescaline became a popular sensation in the mid-20th century through Aldous Huxley's The Doors of Perception, after which the word "psychedelic" was coined to describe it. Its story, however, extends deep into prehistory: The earliest Andean cultures depicted mescaline-containing cacti in their temples.

The extraordinary Siddhartha Mukherjee has written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices.

Beginning with opium, the “joy plant,” which has been used for 10,000 years, Thomas Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.

If you don’t like going to the doctor, spare a thought for your ancestors. Got a headache? We can drill into your skull! Need to buy medicine? Can we recommend a dose of ground-up Egyptian mummy? Want to fight off diseases? Try smelling a stinky cesspit. It’s well-known that to make advances in science you have to make a few mistakes along the way. In this hilarious history book kids will be whisked around the world—from ancient Rome to imperial China—to meet the medical innovators who pushed the boundaries of what was possible, with sometimes disastrous effects.

The authors of the best-selling Bold and The Rise of Superman explore altered states of consciousness and how they can ignite passion, fuel creativity, and accelerate problem solving, in this groundbreaking book in the vein of Daniel Pink's Drive and Charles Duhigg's Smarter Faster Better.

Here is P. T. Barnum's insightful review of humbugs, scams, deceits (and self-deceits) in culture, economics, entertainment, religion, medicine, and more.

For two thousand years, cadavers have been involved in science's boldest strides and weirdest undertakings. They've tested France's first guillotines, ridden the NASA Space Shuttle, been crucified in a Parisian laboratory to test the authenticity of the Shroud of Turin, and helped solve the mystery of TWA Flight 800. For every new surgical procedure, from heart transplants to gender reassignment surgery, cadavers have been there alongside surgeons, making history in their quiet way.

What won't we try in our quest for perfect health, beauty, and the fountain of youth? Well, just imagine a time when doctors prescribed morphine for crying infants. When liquefied gold was touted as immortality in a glass. And when strychnine - yes, that strychnine, the one used in rat poison - was dosed like Viagra. Looking back with fascination, horror, and not a little dash of dark, knowing humor, Quackery recounts the lively, at times unbelievable, history of medical misfires and malpractices.

Based on the film by acclaimed documentary filmmaker Ken Burns, The Mayo Clinic: Faith, Hope, Science chronicles the history of this unique organization, from its roots as an unlikely partnership between a country doctor and a Franciscan order of nuns to its position today as a worldwide model for patient care, research, and education. The book demonstrates how the institution’s remarkable 150-year history continues to inspire the way medicine is practiced there today.

From the author of The Emperor of All Maladies, winner of the Pulitzer Prize, and The Gene, a #1 New York Times bestseller, comes his most spectacular book yet, an exploration of medicine and our radical new ability to manipulate cells. Rich with Mukherjee’s revelatory and exhilarating stories of scientists, doctors, and the patients whose lives may be saved by their work, The Song of the Cell is the third book in this extraordinary writer’s exploration of what it means to be human.