Crippled by lupus at 25, celebrated author Flannery O'Connor was forced to leave New York City and return home to Andalusia, her family farm in Milledgeville, Georgia. Years later, as Flannery is finishing a novel and tending to her menagerie of peacocks, her mother drags her to the wedding of a family friend....

One summer morning, twelve-year-old Edward Adler, his beloved older brother, his parents, and 183 other passengers board a flight in Newark headed for Los Angeles. Among them are a Wall Street wunderkind, a young woman coming to terms with an unexpected pregnancy, an injured veteran returning from Afghanistan, a business tycoon, and a free-spirited woman running away from her controlling husband. Halfway across the country, the plane crashes. Edward is the sole survivor.

Julia Ames, after a youth marked by upheaval and emotional turbulence, has found herself on the placid plateau of mid-life. But Julia has never navigated the world with the equanimity of her current privileged class. Having nearly derailed herself several times, making desperate bids for the kind of connection that always felt inaccessible to her, she finally feels, at age fifty seven, that she has a firm handle on things. She’s unprepared, though, for what comes next.

In this “rich, complex family saga” (USA Today) full of long-buried family secrets, Marilyn Connolly and David Sorenson fall in love in the 1970s, blithely ignorant of all that awaits them. By 2016, they have four radically different daughters, each in a state of unrest.

With her remarkable insight into the human condition and silences that contain multitudes, Elizabeth Strout returns to the town of Crosby, Maine, and to her beloved cast of characters—Lucy Barton, Olive Kitteridge, Bob Burgess, and more—as they deal with a shocking crime in their midst, fall in love and yet choose to be apart, and grapple with the question, as Lucy Barton puts it, “What does anyone’s life mean?”

Detroit, 1960. Lila Pereira is two years old when her angry, abusive father has her mother committed to an asylum. Lila never sees her mother again. Three decades later, having mustered everything she has—brains, charm, talent, blond hair—Lila rises to the pinnacle of American media as the powerful, brilliant executive editor of The Washington Globe. Lila unapologetically prioritizes her career, leaving the rearing of her daughters to her generous husband, Joe. He doesn’t mind—until he does.

Sam and Elena dream of another life. On the island off the coast of Washington where they were born and raised, they and their mother struggle to survive. Sam works on the ferry that delivers wealthy mainlanders to their vacation homes while Elena bartends at the local golf club, but even together they can’t earn enough to get by, stirring their frustration about the limits that shape their existence.

1975 is a time of change in America. The Vietnam War is ending. Muhammad Ali is fighting Joe Frazier. And in the small town of Monta Clare, Missouri, girls are disappearing. When the daughter of a wealthy family is targeted, the most unlikely hero emerges—Patch, a local boy, who saves the girl, and, in doing so, leaves heartache in his wake. Patch and those who love him soon discover that the line between triumph and tragedy has never been finer. And that their search for answers will lead them to truths that could mean losing one another.

At times stern, at other times patient, at times perceptive, at other times in sad denial, Olive Kitteridge, a retired schoolteacher, deplores the changes in her little town of Crosby, Maine, and in the world at large, but she doesn’t always recognize the changes in those around her: a lounge musician haunted by a past romance; a former student who has lost the will to live; Olive’s own adult child, who feels tyrannized by her irrational sensitivities; and her husband, Henry, who finds his loyalty to his marriage both a blessing and a curse.

Early morning, August 1975: a camp counselor discovers an empty bunk. Its occupant, Barbara Van Laar, has gone missing. Barbara isn’t just any thirteen-year-old: she’s the daughter of the family that owns the summer camp and employs most of the region’s residents. And this isn’t the first time a Van Laar child has disappeared. Barbara’s older brother similarly vanished fourteen years ago, never to be found.

The year is 1921. Lesley Hamlyn and her husband, Robert, a lawyer and war veteran, are living at Cassowary House on the Straits Settlement of Penang. When “Willie” Somerset Maugham, a famed writer and old friend of Robert’s, arrives for an extended visit with his secretary Gerald, the pair threatens a rift that could alter more lives than one. Maugham, one of the great novelists of his day, is beleaguered: Having long hidden his homosexuality, his unhappy and expensive marriage of convenience becomes unbearable after he loses his savings—and the freedom to travel with Gerald.

It's 1924 in Branchville, South Carolina, and three women have come to a crossroads. Gertrude, a mother of four, must make an unconscionable decision to save her daughters. Retta, a first-generation freed slave, comes to Gertrude's aid by watching her children, despite the gossip it causes in her community. Annie, the matriarch of the influential Coles family, offers Gertrude employment at her sewing circle, while facing problems of her own at home.

Brecken Hill in upstate New York is an expensive place to live. You have to be rich to have a house there, and Fred and Sheila Merton certainly are rich. But even all their money can't protect them when a killer comes to call. The Mertons are brutally murdered after a fraught Easter dinner with their three adult kids. Who, of course, are devastated.

On the eve of her 40th birthday, Alice’s life isn’t terrible. She likes her job, even if it isn’t exactly the one she expected. She’s happy with her apartment, her romantic status, her independence, and she adores her lifelong best friend. But her father is ailing, and it feels to her as if something is missing. When she wakes up the next morning she finds herself back in 1996, reliving her 16th birthday.

Natural-born healer Emma Starling once had big plans for her life, but she’s lost her way. A medical school dropout, she’s come back to small-town Everton, New Hampshire, to care for her father, who is dying from a mysterious brain disease. Clive Starling has been hallucinating small animals, as well as having visions of the ghost of a long-dead naturalist, Ernest Harold Baynes, once known for letting wild animals live in his house. This ghost has been giving Clive some ideas on how to spend his final days.