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We all go through hard times. We can experience moments when life feels like an uphill struggle, leading to unhappiness and stress. Perhaps we are feeling sad, anxious, or struggling to deal with something bigger, such as a bereavement, a loss, a painful ending or a broken heart. It is during these challenging times that we could do with some help with our thoughts and feelings.

In our never-ending search for happiness we often find ourselves looking to external things for fulfillment, thinking that happiness can be unlocked by buying a bigger house, getting that next promotion, or building a perfect family. In A Monk's Guide to Happiness, Gelong Thubten, a Buddhist monk and meditation expert who has worked with everyone from Ruby Wax and Benedict Cumberbatch to Silicon Valley entrepreneurs, explores the nature of happiness and explains how to bring meditation into our busy 21st-century lives through simple yet effective exercises.

With a little help from a monk (who tells us how our mind works) and a neuroscientist (who tells us how our brain works), Ruby Wax answers every question you've ever had about evolution, thoughts, emotions, the body, addictions, relationships, sex, kids, the future and compassion. Filled with witty anecdotes from Ruby's own life, and backed up by smart science and practical mindfulness exercises, How to be Human is the only manual you need to help you upgrade your mind as much as you've upgraded your iPhone.

Neurologist Ash Ranpura and Buddhist monk Gelong Thubten have recently collaborated with Ruby Wax - comedian, mental health advocate and best-selling author of Frazzled - to produce a new book called How to Be Human: The Manual. In this interview they reveal what they learnt from each other, where they found common ground and where, perhaps, they might disagree. We hear about mindfulness and what science can really tell us about who we are.