Biology Genetics

With trusted expertise from Mayo Clinic, the Edge of Medicine series sets out to inspire and educate the next generation of young scientists by highlighting the medical breakthroughs of a diverse range of scientists and researchers. From the discovery of the double helix to mapping the human genome, this exploration of scientific inquiry celebrates the greatest developments to date in genetics. Get to know the physicians, scientists, and other researchers responsible for these breakthroughs in medicine, and explore the ups, the downs, and the eureka moments that are science in action.

In 1966, Isaac Asimov and Theodosius Dobzhansky wrote The Genetic Effects of Radiation as a public information resource for the US Atomic Energy Commission. In Asimov's typically incisive and easy-to-understand style, the pair presents an overview of genetics, and how inherited traits can be influenced by external factors, including radiation, both environmental and man-made.

The New York Times bestselling author of Genome and The Evolution of Everything revisits Darwin’s revelatory theory of mate choice through the close study of the peculiar rituals of birds, and how understanding this driver of evolution complicates our view of even how human mating evolved. In Birds, Sex, and Beauty, Ridley reopens the history of Darwin’s vexed theory, laying bare a century of disagreement about an idea so powerful, so weird, so wonderful, we may have yet to understand all of its implications.

Riley Black brings listeners back in time to prehistoric seas, swamps, forests, and savannas where critical moments in plant evolution unfolded. Each chapter stars plants and animals alike, underscoring how the interactions between species have helped shape the world we call home. As the chapters move upwards in time, Black guides listeners along the burgeoning trunk of the Tree of Life, stopping to appreciate branches of an evolutionary story that links the world we know with one we can only just perceive now through the silent stone, from ancient roots to the present.

Few of us know much about the biology of sex determination, but what could be more interesting than to discover how we are shaped into males and females? In this book, Elof Carlson tells the incredible story of the difficult quest to understand how the body forms girls and boys. Carlson's history takes us from antiquity to the present day to detail how each component of human reproduction and sexuality was identified and studied....

DNA serves as the basic instruction manual for life. In this installment, we look at the way in which DNA is structured, replicated, and how it is packaged into such a small area. This will provide the basic understanding of how genes are structured in an easy to understand way.

This gives a brief and quick overview of evolutionary theories of the origins of early life at the microscopic levels and the view of how organic substances can come from inorganic substances.

We have long fantasized about finding life on planets other than our own. Yet even as we become aware of the vast expanses beyond our solar system, it remains clear that Earth is exceptional. The question is: Why? In Lucky Planet, astrobiologist David Waltham argues that Earth’s climate stability is what makes it uniquely able to support life, and it is nothing short of luck that made such conditions possible. The four-billion-year stretch of good weather that our planet has experienced is statistically so unlikely that chances are slim that we will ever encounter intelligent extraterrestrial others.

Since the conclusion of the Human Genome Project in 2003, scientists have been racing toward a grand goal: offering individuals a decoding of their complete genetic makeup for just $1,000. As Kevin Davies reveals in this exquisitely reported account, the $1,000 genome will be a reality by 2011 and it will usher in a whole new era of personalized, genomic medicine.

Few people know much about stem cell research beyond the ethical questions raised by using embryos. But in the last decade, stem cell research has made huge advances toward eliminating some of our most intractable diseases. Now this sweeping and accessible book introduces us to this cutting-edge science, which will revolutionize medicine and change the way we think about and treat disease.

In Unfit for Purpose, biologist and broadcaster Adam Hart explores the mismatch between our fundamental biology and the modern world we have created. In each chapter Adam reveals the many ways in which biological adaptations that evolved to help us survive and thrive now work against us. For example, in the modern world stress is a killer, but how did 'fight or flight' instincts turn from life-savers to life-takers? Obesity might be a disease now, but is it really just a troublesome side-effect of our complex evolutionary past?

On the Origin of Species (1859) by Charles Darwin is a work of scientific literature considered to be the foundation of evolutionary biology. The book introduced the theory that populations evolve over the course of generations through a process of natural selection, backed by a body of evidence that the diversity of life arose by common descent through a branching pattern of evolution. The evidence was gathered on the Beagle expedition in the 1830s and the author’s subsequent findings from research, correspondence, and experimentation.

This is the first in a series of "mini" audiobooks on scientists who have provided us with great insights into how nature works. The first audiobook is on Charles Darwin's understanding of natural selection as excerpted from his classic tome On the Origin of Species. Includes a brief introduction by Professor David Christopher Lane, PhD.

From the Siberian permafrost to balmy California, scientists across the globe are working to resurrect all kinds of extinct animals, from ones that just left us to those that have been gone for many thousands of years. Their tools in this hunt are both fossils and cutting-edge genetic technologies. Some of these scientists are driven by sheer curiosity; others view the lost species as a powerful weapon in the fight to preserve rapidly changing ecosystems. It seems certain that these animals will walk the earth again, but what world will that give us? And is any of this a good idea?

In The Genial Gene, Joan Roughgarden forcefully rejects ideas that have come to dominate the study of animal evolution. Building on her brilliant and innovative book Evolution's Rainbow, in which she challenged accepted wisdom about gender identity and sexual orientation, Roughgarden upends the notion of the selfish gene and the theory of sexual selection and develops a compelling and controversial alternative theory called social selection.

In Strange Bedfellows, David P. Barash and Judith Eve Lipton look at how biology actually promotes monogamy in some species and how these lessons apply to human beings. An accessible work of science that is relevant to our intimate daily life, Strange Bedfellows will reassure some people, surprise others, and engage everyone.

Over the past 200 years, human life expectancy has approximately doubled. Yet we face soaring worldwide rates of obesity, diabetes, high blood pressure, mental illness, heart disease, and stroke. In his fascinating new book, Dr. Lee Goldman presents a radical explanation: The key protective traits that once ensured our species' survival are now the leading global causes of illness and death.

In this witty, fact-packed A-Z, Newman takes the listener on a whirlwind tour from caring, sharing vampire bats to intelligent slime mould; from pacifist baboons to Richard Dawkins wrestling naked with his postman; from the invisibility cloak of the Hawaiian bobtail squid to Francis "DNA" Crick's belief that life on Earth began with alien spaceships.

John Tyler Bonner, one of our most distinguished and insightful biologists, here challenges a central tenet of evolutionary biology. In this concise, elegantly written book, he makes the bold and provocative claim that some biological diversity may be explained by something other than natural selection. With his customary wit and accessible style, Bonner makes an argument for the underappreciated role that randomness - or chance - plays in evolution.

While we joke that men are from Mars and women are from Venus, our gender differences can't compare to those of other animals. For instance: the male garden spider spontaneously dies after mating with a female more than fifty times his size. Female cichlids must guard their eggs and larvae--even from the hungry appetites of their own partners. And male blanket octopuses employ a copulatory arm longer than their own bodies to mate with females that outweigh them by four orders of magnitude. Why do these gender gulfs exist?