Biology Genetics

The renowned biologist Paul Nurse has spent his career revealing how living cells work. In What Is Life?, he takes up the challenge of describing what it means to be alive in a way that every listener can understand. It is a shared journey of discovery; step-by-step Nurse illuminates five great ideas that underpin biology - the Cell, the Gene, Evolution by Natural Selection, Life as Chemistry, and Life as Information.

In Survival of the Prettiest, Nancy Etcoff, a faculty member at Harvard Medical School and a practicing psychologist at Massachusetts General Hospital, argues that beauty is neither a cultural construction, an invention of the fashion industry, nor a backlash against feminism - it's in our biology.

Referring to Lewis Carroll's Red Queen from Through the Looking-Glass, a character who has to keep running to stay in the same place, Matt Ridley demonstrates why sex is humanity's best strategy for outwitting its constantly mutating internal predators.

Why is the world the way it is? How did we get here? Does everything happen for a reason, or are some things left to chance? Philosophers and theologians have pondered these questions for millennia, but startling scientific discoveries over the past half century are revealing that we live in a world driven by chance. A Series of Fortunate Events tells the story of the awesome power of chance and how it is the surprising source of all the beauty and diversity in the living world.

In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies - far from the out-of-control nightmare depicted in science fiction - have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span.

An eye-opening look into why our bodies work - or don’t - the way they do. From blurry vision to crooked teeth, ACLs (anterior cruciate ligaments) that tear at alarming rates and spines that seem to spend a lifetime falling apart, it’s surprising that human beings have beaten the odds as a species. After all, we’re the only survivors on our branch of the tree of life. In this funny, wide-ranging and often surprising book, biologist Alex Bezzerides tells us from where we inherited our adaptable, achy, brilliant bodies in the process of evolution.

The domestic cat—your cat—has, from its evolutionary origins in Africa, been transformed in comparatively little time into one of the most successful and diverse species on the planet. Jonathan Losos, writing as both a scientist and a cat lover, explores how researchers today are unraveling the secrets of the cat, past and present, using all the tools of modern technology, from GPS tracking (you’d be amazed where those backyard cats roam) and genomics (what is your so-called Siamese cat . . . really?) to forensic archaeology.

In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field is horizontal gene transfer (HGT), or the movement of genes across species lines. For instance, we now know that roughly eight percent of the human genome arrived not through traditional inheritance from directly ancestral forms, but sideways by viral infection - a type of HGT. In The Tangled Tree David Quammen chronicles these discoveries through the lives of the researchers who made them.

Everywhere there are characteristics of animals that do not want to fit into the theory of evolution anywhere. And man? Are we really the most adapted life-form on this planet? Today, more and more scientists who contradict the previous theory of evolution speak out. The theory fits the changes within the species, but it can no longer be reconciled with the inner workings of the cell. Some other influence that has so far escaped us is affecting evolution. It is called "Intelligent Design." Intelligent planning is suspected behind this.

Mary Roach meets Sam Kean and Bill Bryson in this uproarious tour of the basest instincts and biggest mysteries of the animal world. In The Truth About Animals, Lucy Cooke takes us on a worldwide journey to meet everyone from a Colombian hippo castrator to a Chinese panda porn peddler, all to lay bare the secret - and often hilarious - habits of the animal kingdom. Charming and at times downright weird, this modern bestiary is perfect for anyone who has ever suspected that virtue might be unnatural.

We humans like to think of ourselves as highly evolved creatures. But if we are supposedly evolution's greatest creation, why do we have such bad knees? Why do we catch head colds so often - 200 times more often than a dog does? How come our wrists have so many useless bones? And are we really supposed to swallow and breathe through the same narrow tube? Surely there's been some kind of mistake. As professor of biology Nathan H. Lents explains in Human Errors, our evolutionary history is nothing if not a litany of mistakes, each more entertaining and enlightening than the last.

Cystic fibrosis was once a mysterious disease that killed infants and children. Now it could be the key to healing millions with genetic diseases of every type - from Alzheimer's and Parkinson's to diabetes and sickle cell anemia. Told from the perspectives of the patients, families, physicians, scientists, and philanthropists fighting on the front lines, Breath from Salt is a remarkable story of unlikely scientific and medical firsts, of setbacks and successes, and of people who refused to give up hope....

In his last book, Neil Shubin delved into the amazing connections between human anatomy—our hands, our jaws—and the structures in the fish that first took over land 375 million years ago. Now, with his trademark clarity and exuberance, he takes an even more expansive approach to the question of why we are the way we are.

It may be a wonderful world, but as Dan Riskin explains, it's also a dangerous, disturbing, and disgusting one. At every turn, it seems, living things are trying to eat us, poison us, use our bodies as their homes, or have us spread their eggs. In Mother Nature Is Trying to Kill You, Riskin is our guide through the natural world at its most gloriously ruthless. Using the seven deadly sins as a road map, Riskin offers dozens of jaw-dropping examples that illuminate how brutal nature can truly be.

A giant of archaeology, Colin Renfrew has immeasurably improved our understanding of human history. In this passionately argued work, he offers a concise summary of prehistory - human existence that predates the development of written records - while challenging the very definition of prehistory itself.

Pets have never been more popular. Over half of American households share their home with either a cat or a dog, and many contain both. This is a huge change from only a century ago, when the majority of domestic cats and dogs were working animals, keeping rodents at bay, guarding property, herding sheep. Nowadays, most are valued solely for the companionship they provide. As mankind becomes progressively more urban and detached from nature, we seem to be clinging to the animals that served us well in the past.

Throughout his distinguished and unconventional career, engineer-turned-molecular-biologist Douglas Axe has been asking the questions that much of the scientific community would rather silence. Now, he presents his conclusions in this brave and pioneering book. Axe argues that the key to understanding our origin is the "design intuition" - the innate belief held by all humans that tasks we would need knowledge to accomplish can be accomplished only by someone who has that knowledge.

Seventy years ago, Erwin Schrdinger posed a simple, yet profound, question: What is life?. How could the very existence of such extraordinary chemical systems be understood? This problem has puzzled biologists and physical scientists both before, and ever since. Living things are hugely complex and have unique properties, such as self-maintenance and apparently purposeful behaviour which we do not see in inert matter. So how does chemistry give rise to biology?

How four tools enabled humanity to control its destiny What enabled us to go from simple stone tools to smartphones? How did bands of hunter-gatherers evolve into multinational empires? Listeners of Sapiens will say a cognitive revolution - a dramatic evolutionary change that altered our brains, turning primitive humans into modern ones - caused a cultural explosion. In Transcendence, Gaia Vince argues instead that modern humans are the product of a nuanced coevolution of our genes, environment, and culture that goes back into deep time.

A professor, biologist, and physiologist argues that modern Darwinism's materialist and mechanistic biases have led to a scientific dead end, unable to define what life is - and only an openness to the qualities of "purpose and desire" will move the field forward. J. Scott Turner contends, "To be scientists, we force ourselves into a Hobson's choice on the matter: accept intentionality and purposefulness as real attributes of life, which disqualifies you as a scientist; or become a scientist and dismiss life's distinctive quality from your thinking."