Evolution Health

Cystic fibrosis was once a mysterious disease that killed infants and children. Now it could be the key to healing millions with genetic diseases of every type - from Alzheimer's and Parkinson's to diabetes and sickle cell anemia. Told from the perspectives of the patients, families, physicians, scientists, and philanthropists fighting on the front lines, Breath from Salt is a remarkable story of unlikely scientific and medical firsts, of setbacks and successes, and of people who refused to give up hope....

In his eye-opening new book, Perv, the award-winning columnist and psychologist Jesse Bering argues that we are all sexual deviants on one level or another. As Bering takes us into the lives of a woman who falls madly in love with the Eiffel Tower, a young man addicted to seductive sneezes, and a pair of deeply affectionate identical twins, among others, he challenges us to move beyond our judgments and attitudes toward "deviant" sex and consider the alternative: What would happen if we rise above our fears and revulsions and accepted our true natures?

For all that science knows about the living world, notes David P. Barash, there are even more things we don't know, genuine evolutionary mysteries that perplex the best minds in biology. Paradoxically, many of these mysteries are very close to home, involving some of the most personal aspects of being human. Homo Mysterious examines a number of these evolutionary mysteries, exploring things we don't yet know about ourselves, laying out the best current hypotheses, and pointing toward insights that scientists are just beginning to glimpse.

Throughout history, even as daily life has exhibited calm and tolerance, war has never been far away, and even within societies, violence can be a threat. The Goodness Paradox gives a new and powerful argument for how and why this uncanny combination of peacefulness and violence crystallized after our ancestors acquired language in Africa a quarter of a million years ago.

In Sleepyhead, science writer Henry Nicholls uses his own experience with chronic narcolepsy as a gateway to better understanding the cryptic, curious, and relatively uncharted world of sleep disorders. Charming, eye-opening, and deeply humanizing, Sleepyhead will help us all uncover the secrets of a good night's sleep.

In The Genome Odyssey, Dr. Euan Ashley, Stanford professor of medicine and genetics, brings the breakthroughs of precision medicine to vivid life through the real diagnostic journeys of his patients and the tireless efforts of his fellow doctors and scientists as they hunt to prevent, predict, and beat disease.

How did humans come to be who we are? In his marvelous, eccentric, and widely lauded book Being a Beast, legal scholar, veterinary surgeon, and naturalist extraordinaire Charles Foster set out to understand the consciousness of animal species by living as a badger, otter, fox, deer, and swift. Now, he inhabits three crucial periods of human development to understand the consciousness of perhaps the strangest animal of all—the human being.

Our Political Nature is the first book to reveal the hidden roots of our most deeply held moral values. It shows how political orientations across space and time arise from three clusters of measurable personality traits. These clusters entail opposing attitudes toward tribalism, inequality, and differing perceptions of human nature. Together, these traits are by far the most powerful cause of left-right voting, even leading people to regularly vote against their economic interests.

Nearly every depressed person is assured by doctors, well-meaning friends and family, the media, and ubiquitous advertisements that the underlying problem is a chemical imbalance. Such a simple defect should be fixable, yet despite all of the resources that have been devoted to finding a pharmacological solution, depression remains stubbornly widespread. Why are we losing this fight?

At the age of 27, Whitney Dafoe was forced to give up his life as a photographer who traveled the world. Bit by bit a mysterious illness stole away the pieces of his life: First, it took the strength of his legs, then his voice, and his ability to eat. The Puzzle Solver follows several years in which he desperately sought answers. Whitney's father, Ron Davis, PhD, a world-class geneticist at Stanford University whose legendary research helped crack the code of DNA, suddenly changed the course of his career in a race against time to cure his son's debilitating condition.

For decades medical science has believed that genes determined our biological destiny. Now the new genetics has changed that assumption forever. You will always have the genes you were born with, but genes are dynamic, responding to everything we think, say, and do. Suddenly they've become our strongest allies for personal transformation. When you make lifestyle choices that optimize how your genes behave, you can reach for a state of health and fulfillment undreamed of even a decade ago.

We have learned how to suppress our pain and deny its presence, but when we fight against our internal turmoil, glimmers of peace are short-lived. Rejecting our suffering is not a sustainable solution because trauma is held in the body. In this book, Nityda Gessel invites listeners on a journey toward lasting freedom, with insights and experiential practices that marry the wisdom of Buddhist psychology, yogic teachings, and Indigenous understanding with somatic psychotherapy and neuroscience.

Almost daily, headlines announce newly discovered links between cancers and their genetic causes. Science journalist Jessica Wapner vividly relates the backstory behind those headlines, reconstructing the crucial breakthroughs, explaining the science behind them, and giving due to the dozens of researchers, doctors, and patients whose curiosity and determination restored the promise of a future to the more than 50,000 people diagnosed each year with chronic myeloid leukemia (CML).

How did a deadly genetic disease help our ancestors survive the bubonic plagues of Europe? Was diabetes evolution's response to the last Ice Age? Will a visit to the tanning salon help bring down your cholesterol? Why do we age? Why are some people immune to HIV? Can your genes be turned on or off? Survival of the Sickest reveals the answers to these and many other questions as it unravels the amazing connections between evolution, disease, and human health today.

"It's the animal in us," we often hear when we've been bad. But why not when we're good? Primates and Philosophers tackles this question by exploring the biological foundations of one of humanity's most valued traits: morality.In this provocative book, primatologist Frans de Waal argues that modern-day evolutionary biology takes far too dim a view of the natural world, emphasizing our "selfish" genes.

Since 2010, it has been possible to determine a person's genetic makeup in a matter of days at an accessible cost for many millions of people. Along with this technological breakthrough there has emerged a movement to use this information to help prospective parents "eliminate preventable genetic disease". As the prospect of systematically excluding the appearance of unwanted mutations in our children comes within reach, David B. Goldstein examines the possible consequences from these types of choices.

All of us would like to live longer, or to slow the debilitating effects of age. In How We Age, Coleen Murphy shows how recent research on longevity and aging may be bringing us closer to this goal. Murphy, a leading scholar of aging, explains that the study of model systems, particularly simple invertebrate animals, combined with breakthroughs in genomic methods, have allowed scientists to probe the molecular mechanisms of longevity and aging.

Why are we the way we are? Why do some of us find it impossible to calm a quick temper or to shake anxiety? The debate has always been divided between nature and nurture, but as psychology professor Daniel P. Keating demonstrates in Born Anxious, new DNA science points to a third factor that allows us to inherit both the nature and the nurture of previous generations - with significant consequences.

p53: The Gene That Cracked the Cancer Code reveals the tale of the search for this gene, as well as the excitement of the hunt for new cures - the hype, the lost opportunities, the blind alleys, and the thrilling breakthroughs. As the long-anticipated revolution in cancer treatment tailored to each individual patient's symptoms starts to take off at last, p53 is still at the forefront of the game. This is a timely tale of scientific discovery and advances in our understanding of a disease that still affects more than one in three of us at some point in our lives.

Sex, Time, and Power offers a tantalizing answer to an age-old question: Why did big-brained Homo sapiens suddenly emerge some 150,000 years ago? The key, according to Shlain, is female sexuality. Drawing on an awesome breadth of research, he shows how, long ago, the narrowness of the newly bipedal human female's pelvis and the increasing size of infants' heads precipitated a crisis for the species. Natural selection allowed for reconfiguration of hormonal cycles, entraining women with the periodicity of the moon - and imbuing women with the concept of time.