Genetic History

Just in the last three years a flood of new scientific findings, driven by revelations discovered in the human genome, has provided compelling new answers to many long-standing mysteries about our most ancient ancestors, the people who first evolved in Africa and then went on to colonize the whole world. Nicholas Wade weaves this host of news-making findings together for the first time into an intriguing new history of the human story before the dawn of civilization.

When Bernd Heinrich decided to write a memoir of his ultramarathon running experience, he realized that the preparation for the race was as important, if not more so, than the race itself. In Why We Run, Heinrich considers the flight endurance of birds, the antelope's running prowess and limitations, and the ultra-endurance of camels to understand how human physiology can or cannot replicate these adaptations. Heinrich offers an original and provocative work combining the rigors of science with the passion of running.

Just over 125,000 years ago, humanity was going extinct until a dramatic shift occurred—Homo sapiens started tracking the tides in order to eat the nearby oysters. Before long, they’d pulled themselves back from the brink of extinction. The human brain, and its evolutionary journey, is unlike anything else in history. In A History of the Human Brain, Bret Stetka takes listeners through that far-reaching journey. He also tackles the question of where the brain will take us next, exploring the burgeoning con­cepts of epigenetics and new technologies like CRISPR.

Cystic fibrosis was once a mysterious disease that killed infants and children. Now it could be the key to healing millions with genetic diseases of every type - from Alzheimer's and Parkinson's to diabetes and sickle cell anemia. Told from the perspectives of the patients, families, physicians, scientists, and philanthropists fighting on the front lines, Breath from Salt is a remarkable story of unlikely scientific and medical firsts, of setbacks and successes, and of people who refused to give up hope....

Drawing on startling new evidence from the mapping of the genome, an explosive new account of the genetic basis of race and its role in the human story. Human evolution, the consensus view insists, ended in prehistory. Inconveniently, as Nicholas Wade argues in A Troublesome Inheritance, the consensus view cannot be right. And in fact, we know that populations have changed in the past few thousand years - to be lactose tolerant, for example, and to survive at high altitudes.

How four tools enabled humanity to control its destiny What enabled us to go from simple stone tools to smartphones? How did bands of hunter-gatherers evolve into multinational empires? Listeners of Sapiens will say a cognitive revolution - a dramatic evolutionary change that altered our brains, turning primitive humans into modern ones - caused a cultural explosion. In Transcendence, Gaia Vince argues instead that modern humans are the product of a nuanced coevolution of our genes, environment, and culture that goes back into deep time.

Disorder and chaos ravage London when thousands are contaminated by the accidental discharge of an experimental bio-weapon. The disease robs its hosts of rational thought, giving them a singular desire - find more living flesh to infect. Cut off from information and senior leadership, one squadron of soldiers under the command of their senior NCO, Sergeant Major Johnson, finds itself forced to operate independently until the remnants of military and government command re-establish themselves safely at sea in the English Channel.

With stories that entertain as much as they inform, renowned evolutionist David Sloan Wilson outlines the basic principles of evolution and shows how, when properly understood, they can illuminate the length and breadth of creation, from the origin of life to the nature of religion.

In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field is horizontal gene transfer (HGT), or the movement of genes across species lines. For instance, we now know that roughly eight percent of the human genome arrived not through traditional inheritance from directly ancestral forms, but sideways by viral infection - a type of HGT. In The Tangled Tree David Quammen chronicles these discoveries through the lives of the researchers who made them.

More than any other modern scientists, Stephen Jay Gould has opened up to millions the wonders of evolutionary biology. His genius as an essayist lies in his unmatched ability to use his knowledge of the world, including popular culture, to illuminate the realm of science.

From the very beginning, life on Earth has been defined by war. Today, those first wars continue to be fought around and literally inside us, influencing our individual behavior and that of civilization as a whole. War between populations - whether between different species or between rival groups of humans - is seen as an inevitable part of the evolutionary process. The popular concept of "the survival of the fittest" explains and often excuses these actions.

A giant of archaeology, Colin Renfrew has immeasurably improved our understanding of human history. In this passionately argued work, he offers a concise summary of prehistory - human existence that predates the development of written records - while challenging the very definition of prehistory itself.

Our ability to think about the future is one of the most powerful tools at our disposal. In The Invention of Tomorrow, cognitive scientists Thomas Suddendorf, Jonathan Redshaw, and Adam Bulley argue that its emergence transformed humans from unremarkable primates to creatures that hold the destiny of the planet in their hands. Drawing on their own cutting-edge research, the authors break down the science of foresight, showing us where it comes from, how it works, and how it made our world.

It seems likely that scientists will someday discover how life can emerge on habitable planets like the early Earth and Mars. In Origin of Life: What Everyone Needs to Know, David W. Deamer has written a comprehensive guide to the origin of life that is organized in three sections.

Red is a brilliantly told, captivating history of red hair throughout the ages. An audiobook that breaks new ground, dispels myths, and reinforces the special nature of being a redhead, with a look at multiple disciplines, including science, religion, politics, feminism and sexuality, literature, and art. With an obsessive fascination that is as contagious as it is compelling, author Jacky Colliss Harvey (herself a redhead) begins her exploration of red hair in prehistory and traces the redhead gene as it made its way out of Africa with the early human diaspora.

Who are we? How do scientists define Homo sapiens, and how does our species differ from the extinct hominins that came before us? In this accessible account palaeoarchaeologist Paul Pettitt shows how the latest scientific advances, especially in genetics, are revolutionizing our understanding of human evolution. Pettitt reveals the extraordinary story of how our ancestors adapted to unforgiving and relentlessly changing climates, leading to remarkable innovations in art, technology, and society that we are only now beginning to comprehend.

A Pocket History of Human Evolution brings us up-to-date on the exploits of all our ancient relatives. Paleoanthropologist Silvana Condemi and science journalist François Savatier consider what accelerated our evolution: Was it tools, our "large" brains, language, empathy, or something else entirely? And why are we the sole survivors among many early bipedal humans? Their conclusions reveal the various ways ancient humans live on today - from gossip as modern "grooming" to our gendered division of labor - and what the future might hold for our strange and unique species.

The Galapagos were once known to the sailors and pirates who encountered them as Las Encantadas: the enchanted islands, home to exotic creatures and dramatic volcanic scenery. In The Galapagos, science writer Henry Nicholls offers a lively natural and human history of the archipelago, charting its evolution from deserted wilderness to scientific resource (made famous by Charles Darwin) and global ecotourism hot spot.

Almost daily, headlines announce newly discovered links between cancers and their genetic causes. Science journalist Jessica Wapner vividly relates the backstory behind those headlines, reconstructing the crucial breakthroughs, explaining the science behind them, and giving due to the dozens of researchers, doctors, and patients whose curiosity and determination restored the promise of a future to the more than 50,000 people diagnosed each year with chronic myeloid leukemia (CML).

DNA Demystified satisfies the public appetite for and curiosity about DNA and genetics. The book begins with the basic groundwork and a brief history of DNA and genetics. Chapters then cover newsworthy topics, including DNA fingerprinting, using DNA in forensic analyses, and identifying cold-case criminals. For listeners intrigued by the proliferation of at-home DNA tests, the text includes fascinating explorations of genetic genealogy and family tree construction.