Genetic History

Cystic fibrosis was once a mysterious disease that killed infants and children. Now it could be the key to healing millions with genetic diseases of every type - from Alzheimer's and Parkinson's to diabetes and sickle cell anemia. Told from the perspectives of the patients, families, physicians, scientists, and philanthropists fighting on the front lines, Breath from Salt is a remarkable story of unlikely scientific and medical firsts, of setbacks and successes, and of people who refused to give up hope....

In Origin Story, medical historian Howard Markel recounts the two-year period (1858 to 1860) of Darwin's writing of On the Origin of Species through its spectacular success and controversy. Simultaneously, Markel delves into the mysterious health symptoms Darwin developed, combing the literature to emerge with a cogent diagnosis of a case that has long fascinated medical historians.

Red is a brilliantly told, captivating history of red hair throughout the ages. An audiobook that breaks new ground, dispels myths, and reinforces the special nature of being a redhead, with a look at multiple disciplines, including science, religion, politics, feminism and sexuality, literature, and art. With an obsessive fascination that is as contagious as it is compelling, author Jacky Colliss Harvey (herself a redhead) begins her exploration of red hair in prehistory and traces the redhead gene as it made its way out of Africa with the early human diaspora.

Dive into Evolutionary History, a mesmerizing journey through time, tracing the origins and development of all living beings. From the earliest single-celled organisms to the rise of Homo sapiens, this audiobook unravels the intricate tapestry of evolution with clarity and passion. Explore the wonders of life’s evolution across geological epochs, uncovering the secrets of adaptation, survival, and the remarkable journey of our ancestors.

In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies - far from the out-of-control nightmare depicted in science fiction - have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span.

In its 4.5 billion–year history, life on Earth has been almost erased at least half a dozen times: shattered by asteroid impacts, entombed in ice, smothered by methane, and torn apart by unfathomably powerful megavolcanoes. And we know that another global disaster is eventually headed our way. Can we survive it? How?

As a species, Homo sapiens is at a crossroads. Study of our planet’s turbulent past suggests that we are overdue for a catastrophic disaster, whether caused by nature or by human interference.
It’s a frightening prospect, as each of the Earth’s past major disasters—from meteor strikes to bombardment by cosmic radiation—resulted in a mass extinction, where more than 75 percent of the planet’s species died out. But in Scatter, Adapt, and Remember, Annalee Newitz, science journalist and editor of the science Web site io9.com explains that although global disaster is all but inevitable, our chances of long-term species survival are better than ever. Life on Earth has come close to annihilation—humans have, more than once, narrowly avoided extinction just
during the last million years—but every single time a few creatures survived, evolving to adapt to the harshest of conditions.
This brilliantly speculative work of popular science focuses on humanity’s long history of dodging the bullet, as well as on new threats that we may face in years to come. Most important, it explores how scientific breakthroughs today will help us avoid disasters tomorrow. From simulating tsunamis to studying central Turkey’s ancient underground cities; from cultivating cyanobacteria for “living cities” to designing space elevators to make space colonies cost-effective; from using math to stop pandemics to studying the remarkable survival strategies of gray whales, scientists and researchers the world over are discovering the keys to long-term resilience and learning how humans can choose life over death.
Newitz’s remarkable and fascinating journey through the science of mass extinctions is a powerful argument about human ingenuity and our ability to change. In a world populated by doomsday preppers and media commentators obsessively forecasting our demise, Scatter, Adapt, and Remember is a compelling voice of hope. It leads us away from apocalyptic thinking into a future where we live to build a better world—on this planet and perhaps on others. Readers of this book will be equipped scientifically, intellectually, and emotionally to face whatever the future holds.

The Physics of Life argues that the evolution phenomenon is much broader and older than the evolutionary designs that constitute the biosphere, empowering listeners with a new view of the globe and the future, revealing that the urge to have better ideas has the same physical effect as the urge to have better laws and better government. This is evolution explained loudly but also elegantly, forging a path that flows sustainability.

The scientist who has been dubbed the “Father of Intelligent Design” and author of the groundbreaking book Darwin’s Black Box contends that recent scientific discoveries further disprove Darwinism and strengthen the case for an intelligent creator.

Blending history, science, and culture, a stunning and highly engaging evolutionary story exploring how walking on two legs allowed humans to become the planet’s dominant species.

Evolutions brings to life the latest scientific thinking on the birth of the universe and the solar system, the journey from a single cell all the way to our human minds. Reawakening our sense of wonder and terror at the world around us and within us, Oren Harman uses modern science to create new and original mythologies.

Since 2010, it has been possible to determine a person's genetic makeup in a matter of days at an accessible cost for many millions of people. Along with this technological breakthrough there has emerged a movement to use this information to help prospective parents "eliminate preventable genetic disease". As the prospect of systematically excluding the appearance of unwanted mutations in our children comes within reach, David B. Goldstein examines the possible consequences from these types of choices.

In this provocative history of contemporary debates over evolution, veteran journalist Tom Bethell depicts Darwin's theory as a 19th-century idea past its prime, propped up by logical fallacies, bogus claims, and empirical evidence that is all but disintegrating under an onslaught of new scientific discoveries. Bethell presents a concise yet wide-ranging tour of the flash points of modern evolutionary theory. Bethell's account is enriched by his own personal encounters with of some of our era's leading scientists and thinkers.

The cells in our bodies consist of molecules, made up of the same carbon, oxygen, and hydrogen atoms found in air and rocks. But molecules, such as water and sugar, are not alive. So how do our cells - assemblies of otherwise "dead" molecules - come to life, and together constitute a living being? In Life’s Ratchet, physicist Peter M. Hoffmann locates the answer to this age-old question at the nanoscale.

Best-selling author Brian Fagan brings early humans out of the deep freeze with his trademark mix of erudition, cutting-edge science, and vivid storytelling. Cro-Magnon reveals human society in its infancy, facing enormous environmental challenges - including a rival species of humans, the Neanderthals. For ten millennia, Cro-Magnons lived side by side with Neanderthals, an encounter that Fagan fills with drama.

Everyone has heard the story of DNA as the story of Watson, Crick, and Rosalind Franklin, but knowing the structure of DNA was only part of a greater struggle to understand life's secrets. Life's Greatest Secret is the story of the discovery and cracking of the genetic code, the thing that ultimately enables a spiraling molecule to give rise to the life that exists all around us. This great scientific breakthrough has had far-reaching consequences for how we understand ourselves and our place in the natural world.

In Life Finds a Way, biologist Andreas Wagner reveals the deep symmetry between innovation in biological evolution and human cultural creativity. Rarely is either a linear climb to perfection - instead, "progress" is typically marked by a sequence of peaks, plateaus, and pitfalls. For instance, in Picasso's 40-some iterations of Guernica, we see the same combination of small steps, incessant reshuffling, and large, almost reckless, leaps that characterize the way evolution transformed a dinosaur's grasping claw into a condor's soaring wing.

Taking us on an incredible journey across centuries and galaxies, accompanied by his characteristic wit, Professor Luke O’Neill explains how it all began, how it will all end and everything in between. Listeners will benefit from Luke’s insatiable curiosity for life when they dive into this ultimate journey through life and death. Among other fascinating facts, you’ll discover the science behind how we got to be so smart, why sex with a caveman was a good idea, the science of finding love, why we follow religions and how robots will become part of everyday life.

In his last book, Neil Shubin delved into the amazing connections between human anatomy—our hands, our jaws—and the structures in the fish that first took over land 375 million years ago. Now, with his trademark clarity and exuberance, he takes an even more expansive approach to the question of why we are the way we are.

In Born in Africa, Martin Meredith follows the trail of discoveries about human origins made by scientists over the last hundred years, recounting their intense rivalry, personal feuds, and fierce controversies, as well as their feats of skill and endurance. The results have been momentous. Scientists have identified more than 20 species of extinct humans. They have firmly established Africa as the birthplace not only of humankind but also of modern humans.

An almost limitless archive of our history lies hidden inside our bodies, and this book traces the ancient story of Scotland from that scientific viewpoint. The mushrooming of genetic studies, of DNA analysis, is rewriting history in spectacular fashion. In Scotland: A Genetic Journey, Alistair Moffat explores the history that is printed on our genes, and in a remarkable new approach, uncovers the detail of where Scots are from, where they have journeyed, and who they are - and in so doing, vividly colors in a DNA map of Scotland.