Genetics Health

In the early 1800s, a century before there was any concept of the gene, physicians in insane asylums began to record causes of madness in their admission books. Almost from the beginning, they pointed to heredity as the most important of these causes. As doctors and state officials steadily lost faith in the capacity of asylum care to stem the terrible increase of insanity, they began emphasizing the need to curb the reproduction of the insane. They became obsessed with identifying weak or tainted families and anticipating the outcomes of their marriages.

Self Comes to Mind is a nuanced and original chronicle of the evolution of the human brain. It reveals how the brain's development of a self becomes a challenge to nature's indifference and opens the way for the appearance of culture, a radical break in the course of evolution.

Short, sassy, and bold, Mean Genes reveals that our struggles for self-improvement are, in fact, battles against our own genes - genes that helped our distant ancestors flourish, but are selfish and out of place in the modern world.

More than three decades ago, Dr. Herbert Benson of Harvard Medical School proposed a theory in his multimillion-copy best seller The Relaxation Response, which stated that by calming the mind, one could calm the body and alleviate stress, pain, and illness.

Did you know women walk more, eat less, socialize more, meet more men, dance more, and flirt more when they're ovulating? Or that PMS may have evolved to get rid of boyfriends with unfit sperm? Behind the "fickle" differences in what women find sexy about men, or what they like to wear, there's a hidden adaptive intelligence shaped over eons. Rather than making women irrational - as the conventional and irredeemably sexist wisdom goes - the female hormonal cycle has been exquisitely fine-tuned to give women the advantages they needed to succeed in our ancestral environments, and perhaps also today.

Dive into Evolutionary History, a mesmerizing journey through time, tracing the origins and development of all living beings. From the earliest single-celled organisms to the rise of Homo sapiens, this audiobook unravels the intricate tapestry of evolution with clarity and passion. Explore the wonders of life’s evolution across geological epochs, uncovering the secrets of adaptation, survival, and the remarkable journey of our ancestors.

You've probably seen it before: a human brain dramatically lit from the side, the camera circling it like a helicopter shot of Stonehenge, and a modulated baritone voice exalting the brain's elegant design in reverent tones... to which this book says: Pure nonsense.

Since 2010, it has been possible to determine a person's genetic makeup in a matter of days at an accessible cost for many millions of people. Along with this technological breakthrough there has emerged a movement to use this information to help prospective parents "eliminate preventable genetic disease". As the prospect of systematically excluding the appearance of unwanted mutations in our children comes within reach, David B. Goldstein examines the possible consequences from these types of choices.

A leading brain scientist's look at the neurobiology of pleasure-and how pleasures can become addictions. Whether eating, taking drugs, engaging in sex, or doing good deeds, the pursuit of pleasure is a central drive of the human animal. In The Compass of Pleasure Johns Hopkins neuroscientist David J. Linden explains how pleasure affects us at the most fundamental level: in our brain.

Noted scientist David P. Barash explores the process by which science has, throughout time, cut humanity "down to size", and how humanity has responded. A good paradigm is a tough thing to lose, especially when its replacement leaves us feeling more vulnerable and less special. And yet, as science has progressed, we find ourselves - like it or not - bereft of many of our most cherished beliefs, confronting an array of paradigms lost. Barash models his argument around a set of "old" and "new" paradigms that define humanity's place in the universe.

For all that science knows about the living world, notes David P. Barash, there are even more things we don't know, genuine evolutionary mysteries that perplex the best minds in biology. Paradoxically, many of these mysteries are very close to home, involving some of the most personal aspects of being human. Homo Mysterious examines a number of these evolutionary mysteries, exploring things we don't yet know about ourselves, laying out the best current hypotheses, and pointing toward insights that scientists are just beginning to glimpse.

In this startling study of human emotion, Dacher Keltner investigates an unanswered question of human evolution: If humans are hardwired to lead lives that are "nasty, brutish, and short," why have we evolved with positive emotions like gratitude, amusement, awe, and compassion that promote ethical action and cooperative societies? Born to Be Good takes us on a journey through scientific discovery, personal narrative, and Eastern philosophy.

Why are we the way we are? Why do some of us find it impossible to calm a quick temper or to shake anxiety? The debate has always been divided between nature and nurture, but as psychology professor Daniel P. Keating demonstrates in Born Anxious, new DNA science points to a third factor that allows us to inherit both the nature and the nurture of previous generations - with significant consequences.

Breakthroughs in genetics present us with a promise and a predicament. The promise is that we will soon be able to treat and prevent a host of debilitating diseases. The predicament is that our newfound genetic knowledge may enable us to manipulate our nature - to enhance our genetic traits and those of our children. Although most people find at least some forms of genetic engineering disquieting, it is not easy to articulate why.

In Mercies in Disguise, acclaimed New York Times reporter and best-selling author Gina Kolata tells the story of the Baxleys, an upstanding family in small-town South Carolina. Many of them were doctors, but still, they are struck down by an inscrutable illness. Finally they discover the cause of the disease after a remarkable sequence of providential events. Meanwhile science, progressing for 50 years along a parallel track, handed the Baxleys a question - not a cure but a blood test that would reveal who had the gene for the disease.

Unblinded is the true story of New Yorker Kevin Coughlin, who became blind at age 36 due to a rare genetic disorder known as Leber's hereditary optic neuropathy. Twenty years later, without medical intervention, Kevin's sight miraculously started to return. He is the only known person in the world who has experienced a spontaneous, non-medically assisted regeneration of the optic nerve. Unblinded follows Kevin's descent into darkness and his unexplained reemergence to sight.

In Life Finds a Way, biologist Andreas Wagner reveals the deep symmetry between innovation in biological evolution and human cultural creativity. Rarely is either a linear climb to perfection - instead, "progress" is typically marked by a sequence of peaks, plateaus, and pitfalls. For instance, in Picasso's 40-some iterations of Guernica, we see the same combination of small steps, incessant reshuffling, and large, almost reckless, leaps that characterize the way evolution transformed a dinosaur's grasping claw into a condor's soaring wing.

Since dyslexia was first described in the British Medical Journal in 1896, there has been debate about the definitions and diagnostic procedures used, with some casting doubt on its very existence. However, there is now a considerable body of research regarding the nature and characteristics of this relatively common learning disorder. The contemporary view of dyslexia has emerged from a century of research in medicine, psychology, and more recently, neuroscience, and we now understand enough about this learning disorder to guide policy and practice.

We have long attributed man's violent, aggressive, competitive nature to his animal ancestry. But what if we are just as given to cooperation, empathy, and morality by virtue of our genes? What if our behavior actually makes us apes? What kind of apes are we?

Jamie Tyrone was 49 years old when she learned she had a 91% chance of getting Alzheimer's disease - by accident through genetic testing. She was shocked, but after an initial bout with depression she decided to take action rather than concede defeat. Jamie teamed up with Dr. Marwan Sabbagh, a renowned neurologist, and together they created a resource detailing not just Jamie's experience, but expert medical advice for anyone facing the disease.