History Medicine Science

In 1953, a 27-year-old factory worker named Henry Molaison - who suffered from severe epilepsy - received a radical new version of the then-common lobotomy, targeting the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry was left profoundly amnesic, unable to create long-term memories. Over the next 60 years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.

In The Poisoner's Handbook, Blum draws from highly original research to track the fascinating, perilous days when a pair of forensic scientists began their trailblazing chemical detective work, fighting to end an era when untraceable poisons offered an easy path to the perfect crime.

Dr. Lange graduated from medical school in 1981, right as a new plague swept across the globe. His story became intertwined with the story of HIV. At once a physician, scientist, AIDS activist, and medical diplomat, Lange studied ways to battle HIV and prevent its spread from mother to child. Fighting the injustices of poverty, Lange advocated for better access to health care for the poor and the vulnerable. The Impatient Dr. Lange is the story of one man's struggle against a global pandemic - and the tragic attack that may have slowed down the search for a cure.

Until the 1970s, if you suffered a medical crisis, your chances of survival were minimal. A 9-1-1 call might bring police or even the local funeral home. But that all changed with Freedom House EMS in Pittsburgh, a group of Black men who became America’s first paramedics and set the gold standard for emergency medicine around the world, only to have their story and their legacy erased—until now.

In 1920, at the end of the last major pandemic, global life expectancy was just over 40 years. Today, in many parts of the world, human beings can expect to live more than 80 years. As a species, we have doubled our life expectancy in just one century. There are few measures of human progress more astonishing than this increased longevity.

During the height of the COVID-19 pandemic, one renowned scientist, in his famous bowtie, appeared daily on major news networks such as MSNBC, NPR, the BBC, and others. Dr. Peter J. Hotez often went without sleep, working around the clock to develop a nonprofit COVID-19 vaccine and to keep the public informed. During that time, he was one of the most trusted voices on the pandemic and was even nominated for a Nobel Peace Prize for his selfless work. He also became one of the main targets of anti-science rhetoric that gained traction through conservative news media.

Between 1927 and 1979, more than 8,000 people were involuntarily sterilized in five hospitals across the state of Virginia. From this plain and terrible fact springs Elizabeth Catte's Pure America, a sweeping, unsparing history of eugenics in Virginia, and by extension the United States.

Rabies enjoys a fearsome and lurid reputation. Throughout the decades of spiraling growth that defined New York City from the 1840s to the 1910s, the bone-chilling cry of "Mad dog!" possessed the power to upend the ordinary routines and rhythms of urban life. In Mad Dogs and Other New Yorkers, Jessica Wang examines the history of this rare but dreaded affliction during a time of rapid urbanization.

In the spring of 1940, the aspiring but unknown writer Albert Camus and budding scientist Jacques Monod were quietly pursuing ordinary, separate lives in Paris. After the German invasion and occupation of France, each joined the Resistance to help liberate the country from the Nazis and ascended to prominent, dangerous roles. After the war and through twists of circumstance, they became friends, and through their passionate determination and rare talent they emerged as leading voices of modern literature and biology, each receiving the Nobel Prize in their respective fields.

This riveting audiobook takes the listener around the globe and through the centuries to discover how different cultures have sought to combat and treat physical pain. With colorful stories and sometimes frightening anecdotes, Dr. Thomas Dormandy describes a checkered progression of breakthroughs, haphazard experiments, ignorant attitudes, and surprising developments in human efforts to control pain.

The story of the Internet begins in the early 1960s, when Russia launched Sputnik 1, the first artificial earth satellite. Afraid of the technological potential of the Russians, the United States Department of Defense formed the Advanced Research Projects Agency (ARPA), in order to develop US science and technology, and in particular its application in the military.

James A. Garfield may have been the most extraordinary man ever elected president. Born into abject poverty, he rose to become a wunderkind scholar, a Civil War hero, and a renowned and admired reformist congressman. Nominated for president against his will, he engaged in a fierce battle with the corrupt political establishment. But four months after his inauguration, a deranged office seeker tracked Garfield down and shot him in the back. But the shot didn’t kill Garfield. The drama of what hap­pened subsequently is a powerful story of a nation in tur­moil.

Early studies of the human brain used a simple method: Wait for misfortune to strike - strokes, seizures, infectious diseases, horrendous accidents - and see how victims coped. In many cases their survival was miraculous, if puzzling. Observers were amazed by the transformations that took place when different parts of the brain were destroyed, altering victims' personalities. With the lucid, masterful explanations and razor-sharp wit his fans have come to expect, Kean explores the brain's secret passageways.

In Out Cold, science writer Phil Jaekl chronicles the underappreciated story of human innovation with cold, from Ancient Egypt, where it was used to treat skin irritations, to 18th-century London, where scientists used it in their first explorations of suspended animation. Throughout history, physicians have used cold to innovate life extension, enable distant space missions, and explore consciousness.

G. Wayne Miller has dramatically and meticulously reconstructed an amazing true story: how a group of renegade Minnesota surgeons, led by Dr. Walt Lillehei, made medical history by becoming the first doctors to operate deep inside the human heart.

Considered the definitive history of the American healthcare system, The Social Transformation of American Medicine examines how the roles of doctors, hospitals, health plans, and government programs have evolved over the last two and a half centuries. Updated with a new preface and an epilogue analyzing developments since the early 1980s, this new edition is a must-listen for anyone concerned about the future of our fraught healthcare system.

Today, astonishing surgical breakthroughs are making limb transplants, face transplants, and a host of other previously undreamed-of operations possible. But getting here has not been a simple story of medical progress. In Blood and Guts, veteran science writer Richard Hollingham weaves a compelling narrative from the key moments in surgical history. We have a ringside seat in the operating theater of University College Hospital in London as world-renowned Victorian surgeon Robert Liston performs a remarkable amputation in 30 seconds - from first cut to final stitch.

At the height of World War I, history’s most lethal influenza virus erupted in an army camp in Kansas, moved east with American troops, then exploded, killing as many as 100 million people worldwide. It killed more people in twenty-four months than AIDS killed in twenty-four years, more in a year than the Black Death killed in a century. But this was not the Middle Ages, and 1918 marked the first collision of science and epidemic disease.

At the University of Wisconsin, Dr. Joshua Mezrich creates life from loss, transplanting organs from one body to another. In this intimate, profoundly moving work, he illuminates the extraordinary field of transplantation that enables this kind of miracle to happen every day.

It wasn’t supposed to be this hard. If America could send a man to the moon, shouldn’t the best surgeons in the world be able to build an artificial heart? In Ticker, Texas Monthly executive editor and two time National Magazine Award winner Mimi Swartz shows just how complex and difficult it can be to replicate one of nature’s greatest creations. Part investigative journalism, part medical mystery, Ticker is a dazzling story of modern innovation, recounting 50 years of false starts, abysmal failures, and miraculous triumphs.