Medical History

Physician, researcher, and ethics professor Matt McCarthy is on the front lines of a groundbreaking clinical trial testing a new antibiotic to fight lethal superbugs, bacteria that have built up resistance to the life-saving drugs in our rapidly dwindling arsenal. This trial serves as the backdrop for the compulsively listenable Superbugs, and the results will impact nothing less than the future of humanity.

The Lobotomist explores one of the darkest chapters of American medicine: the desperate attempt to treat the hundreds of thousands of psychiatric patients in need of help during the middle decades of the 20th century. Into this crisis stepped Walter Freeman, MD, who saw a solution in lobotomy, a brain operation intended to reduce the severity of psychotic symptoms. Drawing on Freeman's documents and interviews with Freeman's family, Jack El-Hai takes a penetrating look at the life and work of this complex scientific genius.

In 1953, a 27-year-old factory worker named Henry Molaison - who suffered from severe epilepsy - received a radical new version of the then-common lobotomy, targeting the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry was left profoundly amnesic, unable to create long-term memories. Over the next 60 years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.

Author Leslie Lehr wants to talk about boobs. She’s gone from size AA to DDD and everything between, from puberty to motherhood, enhancement to cancer, and beyond. And she’s not alone - these are classic life stages for women today. At turns funny and heartbreaking, A Boob’s Life explores both the joys and hazards inherent to living in a woman’s body. Lehr deftly blends her personal narrative with national history, starting in the 1960s with the women’s liberation movement and moving to the current feminist dialogue and what it means to be a woman.

Jeanne Marie Laskas first met the young forensic pathologist Dr. Bennet Omalu in 2009, while reporting a story for GQ that would go on to inspire the movie Concussion. Omalu told her about a day in September 2002, when, in a dingy morgue in downtown Pittsburgh, he picked up a scalpel and made a discovery that would rattle America in ways he’d never intended. Omalu was new to America, chasing the dream, a deeply spiritual man escaping the wounds of civil war in Nigeria.

In January 1918, as World War I raged on, a new and terrifying virus began to spread across the globe. In three successive waves, from 1918 to 1919, influenza killed more than 50 million people. German soldiers termed it Blitzkatarrh, British soldiers referred to it as Flanders Grippe, but worldwide, the pandemic gained the notorious title of “Spanish flu”. Nowhere on earth escaped: the United States recorded 550,000 deaths (five times its total military fatalities in the war) while European deaths totaled more than two million.

This gripping book traces the evolution of brainwashing from its beginnings in torture and religious conversion into the age of neuroscience and social media. When Pavlov introduced scientific approaches, his research was enthusiastically supported by Lenin and Stalin, setting the stage for major breakthroughs in tools for social, political, and religious control.

In the early 1800s, a century before there was any concept of the gene, physicians in insane asylums began to record causes of madness in their admission books. Almost from the beginning, they pointed to heredity as the most important of these causes. As doctors and state officials steadily lost faith in the capacity of asylum care to stem the terrible increase of insanity, they began emphasizing the need to curb the reproduction of the insane. They became obsessed with identifying weak or tainted families and anticipating the outcomes of their marriages.

More than four hundred abandoned suitcases filled with patients’ belongings were found when Willard Psychiatric Center closed in 1995 after 125 years of operation. They are skillfully examined here and compared to the written record to create a moving—and devastating—group portrait of twentieth-century American psychiatric care.

In Origin Story, medical historian Howard Markel recounts the two-year period (1858 to 1860) of Darwin's writing of On the Origin of Species through its spectacular success and controversy. Simultaneously, Markel delves into the mysterious health symptoms Darwin developed, combing the literature to emerge with a cogent diagnosis of a case that has long fascinated medical historians.

Cystic fibrosis was once a mysterious disease that killed infants and children. Now it could be the key to healing millions with genetic diseases of every type - from Alzheimer's and Parkinson's to diabetes and sickle cell anemia. Told from the perspectives of the patients, families, physicians, scientists, and philanthropists fighting on the front lines, Breath from Salt is a remarkable story of unlikely scientific and medical firsts, of setbacks and successes, and of people who refused to give up hope....

In 1907 Sigmund Freud and Carl Gustav Jung began what promised to be both a momentous collaboration and the deepest friendship of each man's life. Six years later they were bitter antagonists, locked in a savage struggle that was as much personal and emotional as it was theoretical and professional. In between them stood a young woman named Sabina Spielrein, who had been both patient and lover to Jung and colleague and confidante to Freud before going on to become an innovative psychoanalyst herself.

Was Andy Warhol a hoarder? Did Einstein have autism? Was Frank Lloyd Wright a narcissist? In this surprising, inventive, and meticulously researched look at the evolution of mental health, acclaimed health and science journalist Claudia Kalb gives listeners a glimpse into the lives of high-profile historic figures through the lens of modern psychology, weaving groundbreaking research into biographical narratives that are deeply embedded in our culture.

An acclaimed medical expert and patient advocate offers an eye-opening look at many common and widely used medical interventions that have been shown to be far more harmful than helpful. Yet, surprisingly, despite clear evidence to the contrary, most doctors continue to recommend them.

Ingrassia lost his mother, two sisters, brother, and nephew to cancer—different cancers developing at different points throughout their lives. And while highly unusual, his family is not the only one to wonder whether their heartbreak is the result of unbelievable bad luck, or if there might be another explanation. Through meticulous research and riveting storytelling, Ingrassia takes us from the 1960s—when Dr. Frederick Pei Li and Dr. Joseph Fraumeni Jr. first met, not yet knowing that they would help make a groundbreaking discovery that would affect cancer patients for decades to come.

Larry Brilliant's life journey has led him on a purposeful path across continents and countercultural movements, marching arm in arm with the men and women who defined a generation. A man who has always been in the right place at the right time, Brilliant has engaged with some of the most prominent thought leaders, spiritual masters, heroes, and icons in the world, including Neem Karoli Baba (Maharajji), Martin Luther King Jr., Steve Jobs, Mikhail Gorbachev, Wavy Gravy, the Grateful Dead, the Dalai Lama, and Barack Obama.

The idea that medicine is gender-neutral is a myth. This isn't inflammatory rhetoric; it's simply true. From the way pain is felt, to how heart attacks are diagnosed, to the very role society plays in the health of the body, the medical landscape in place today is one that was designed for, and by, men. This audiobook is about all the ways medicine is not gender-neutral, from research to treatment to diagnosis. Throughout history, flawed mindsets have paved the way for sub-par treatment, and the prevailing attitudes that exist today have had terrible repercussions for women.

In Out Cold, science writer Phil Jaekl chronicles the underappreciated story of human innovation with cold, from Ancient Egypt, where it was used to treat skin irritations, to 18th-century London, where scientists used it in their first explorations of suspended animation. Throughout history, physicians have used cold to innovate life extension, enable distant space missions, and explore consciousness.

Patti Davis, the daughter of Ronald and Nancy Reagan, writes about losing her father to Alzheimer's disease, saying goodbye in stages, and watching the progression of a disease that steals what is most precious: a person's memory. Past and present come together in this illuminating portrait of grief, of a man, a disease, and a girl and her father.

In 1959, a Cincinnati pharmaceutical firm, the William S. Merrell Company, quietly began distributing samples of an exciting new wonder drug already popular around the world. Touted as a sedative without risks, thalidomide was handed out freely, under the guise of clinical trials, by doctors who believed approval by the Food and Drug Administration was imminent. But in 1960, when the application for thalidomide landed on the desk of FDA medical reviewer Frances Kelsey, she quickly grew suspicious.