Medical History

Cystic fibrosis was once a mysterious disease that killed infants and children. Now it could be the key to healing millions with genetic diseases of every type - from Alzheimer's and Parkinson's to diabetes and sickle cell anemia. Told from the perspectives of the patients, families, physicians, scientists, and philanthropists fighting on the front lines, Breath from Salt is a remarkable story of unlikely scientific and medical firsts, of setbacks and successes, and of people who refused to give up hope....

Larry Brilliant's life journey has led him on a purposeful path across continents and countercultural movements, marching arm in arm with the men and women who defined a generation. A man who has always been in the right place at the right time, Brilliant has engaged with some of the most prominent thought leaders, spiritual masters, heroes, and icons in the world, including Neem Karoli Baba (Maharajji), Martin Luther King Jr., Steve Jobs, Mikhail Gorbachev, Wavy Gravy, the Grateful Dead, the Dalai Lama, and Barack Obama.

For centuries, the human heart seemed beyond our understanding: an inscrutable shuddering mass that was somehow the driver of emotion and the seat of the soul. As cardiologist and best-selling author Sandeep Jauhar tells in The Heart, it was only recently that we demolished age-old taboos and devised the transformative procedures that changed the way we live. Deftly alternating between historical episodes and his own work, Jauhar tells the colorful and little known story of the doctors who risked their careers and the patients who risked their lives to know and heal our most vital organ.

In this new book, Kidder gives us the superb story of a hero for our time. Strength in What Remains is a wonderfully written, inspiring account of one man’s remarkable American journey and of the ordinary people who helped him–a brilliant testament to the power of will and of second chances.

From the 15th to the mid-19th centuries, scurvy caused more deaths at sea than storms, shipwrecks, combat, and all other diseases combined. The cure for scurvy ranks among the greatest of military successes, yet its impact on history has mostly been ignored. In this book, Stephen R. Brown delivers a lively recounting of how three determined individuals overcame the constraints of 18th century thinking to solve the greatest medical mystery of their era. Brimming with tales of ships, sailors, and bureaucracy, Brown presents a vivid picture of life aboard the ship during the age of sail.

Country of Ash is the starkly compelling, original chronicle of a Jewish doctor who miraculously survived near-certain death, first inside the Lodz and Warsaw ghettoes, where he was forced to treat the Gestapo, then on the Aryan side of Warsaw, where he hid under numerous disguises. He clandestinely recorded the terrible events he witnessed, but his manuscript disappeared during the Warsaw Ghetto Uprising. After the war, reunited with his wife and young daughter, he rewrote his story.

In Out Cold, science writer Phil Jaekl chronicles the underappreciated story of human innovation with cold, from Ancient Egypt, where it was used to treat skin irritations, to 18th-century London, where scientists used it in their first explorations of suspended animation. Throughout history, physicians have used cold to innovate life extension, enable distant space missions, and explore consciousness.

In 1953, a 27-year-old factory worker named Henry Molaison - who suffered from severe epilepsy - received a radical new version of the then-common lobotomy, targeting the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry was left profoundly amnesic, unable to create long-term memories. Over the next 60 years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.

At the age of 27, married, living in New York, and working in book design, Mary Cregan gives birth to her first child, a daughter she names Anna. But it’s apparent that something is terribly wrong, and two days later, Anna dies - plunging Cregan into suicidal despair. Decades later, sustained by her work, a second marriage, and a son, Cregan reflects on this pivotal experience and attempts to make sense of it. She weaves together literature and research with details from her own ordeal - and the still visible scar of her suicide attempt....

Metabolism, behavior, sleep, mood swings, the immune system, fighting, fleeing, puberty, and sex: these are just a few of the things our bodies control with hormones. Armed with a healthy dose of wit and curiosity, Randi Hutter Epstein takes us on a journey through the unusual history of these potent chemicals and their discovery, from the London laboratory where the concept of hormones was identified to a basement filled with jarred brains to a canine sex lab.

From insulin comas and lobotomy to incarceration and exile, Walter Brown chronicles the troubling history of the diagnosis and (often ineffective) treatment of bipolar disorder through the centuries, before the publication of a groundbreaking research paper in 1949. Cade's "Lithium Salts in the Treatment of Psychotic Excitement" described, for the first time, lithium's astonishing efficacy at both treating and preventing the recurrence of manic-depressive episodes, and would eventually transform the lives of patients, pharmaceutical researchers, and practicing physicians worldwide.

It wasn’t supposed to be this hard. If America could send a man to the moon, shouldn’t the best surgeons in the world be able to build an artificial heart? In Ticker, Texas Monthly executive editor and two time National Magazine Award winner Mimi Swartz shows just how complex and difficult it can be to replicate one of nature’s greatest creations. Part investigative journalism, part medical mystery, Ticker is a dazzling story of modern innovation, recounting 50 years of false starts, abysmal failures, and miraculous triumphs.

G. Wayne Miller has dramatically and meticulously reconstructed an amazing true story: how a group of renegade Minnesota surgeons, led by Dr. Walt Lillehei, made medical history by becoming the first doctors to operate deep inside the human heart.

Flight for Life is the heart-stopping account of one of the most gripping rescue missions in African history, told by a doctor involved in saving the lives of Nigerian workers who became victims of a tragic American chemical company explosion. Dr. Stewart and his colleague moved mountains and cut red tape to fly patients to one of the premiere burn centers in the United States.

On January 12, 2010, a major earthquake struck near Port-au-Prince, Haiti. Hundreds of thousands of people died, and the greater part of the capital was demolished. Dr. Paul Farmer, U.N. deputy special envoy to Haiti, who had worked in the country for nearly thirty years treating infectious diseases like tuberculosis and AIDS, and former President Bill Clinton, the U.N. special envoy to Haiti, had just begun to work on an extensive development plan to improve living conditions in Haiti.

Caroline Crampton’s life was upended at the age of seventeen, when she was diagnosed with Hodgkin’s lymphoma, a relatively rare blood cancer. After years of invasive treatment, she was finally given the all clear. But being cured of the cancer didn’t mean she felt well. Instead, the fear lingered, and she found herself always on the alert, braced for signs that the illness had reemerged.

Based on the film by acclaimed documentary filmmaker Ken Burns, The Mayo Clinic: Faith, Hope, Science chronicles the history of this unique organization, from its roots as an unlikely partnership between a country doctor and a Franciscan order of nuns to its position today as a worldwide model for patient care, research, and education. The book demonstrates how the institution’s remarkable 150-year history continues to inspire the way medicine is practiced there today.

Considering herself unsuitable for any other contribution to the war effort, Monica Dickens opts for nursing, imagining herself gliding through the wards, serene in a pure white halo cap. On enrolment, however, she is promptly stripped of all illusions. Intelligent and headstrong, Monica struggles to submit to the iron rule of the Matron and toils over the mountains of menial work that are a trainee's lot. But there are friends among the staff and patients, night-time escapades to dances with dashing army men and her secret writing project to keep her going.

In the quarter century that Victoria Sweet has been a doctor, "health care" has replaced medicine, "providers" (vastly outnumbered by administrators) look at their laptops more than at their patients, and the ruthless pursuit of efficiency has vanquished not only trust and intimacy but also, often, the effectiveness of treatment. Victoria Sweet knows that there is an alternative way, because she has lived and practiced it. In her new book, she reflects with compassion, wit, and profound insight.

Americans are in the midst of a world-historic drug binge. Opiates, amphetamines, benzodiazepines, marijuana, antidepressants, antipsychotics—across the board, consumption has shot up in the twenty-first century. At the same time, the United States is home to the largest prison system in the world, justified in part by a now zombified "war" on drugs. How did we get here?