Medical History

Weaving together family history, genetic discovery, and scenes from her life, Ami McKay tells the compelling, true-science story of her own family's unsettling legacy of hereditary cancer while exploring the challenges that come from carrying the mutation that not only killed many people you loved, but might also kill you.

In Out Cold, science writer Phil Jaekl chronicles the underappreciated story of human innovation with cold, from Ancient Egypt, where it was used to treat skin irritations, to 18th-century London, where scientists used it in their first explorations of suspended animation. Throughout history, physicians have used cold to innovate life extension, enable distant space missions, and explore consciousness.

In 1953, a 27-year-old factory worker named Henry Molaison - who suffered from severe epilepsy - received a radical new version of the then-common lobotomy, targeting the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry was left profoundly amnesic, unable to create long-term memories. Over the next 60 years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.

Due to horrible physical deformities, he spent much of his life as a fairground freak. He was hounded, persecuted, and starving, until his fortune changed and he was rescued, housed, and fed by the distinguished surgeon, Frederick Treves. The subject of several books, a Broadway hit, and a film, Joseph Merrick has become part of popular mythology. Here, in this fully revised edition containing much fresh information, are the true and un-romanticized facts of his life.

Against a global backdrop of wartime suffering and postwar hope, Borrowing Life gathers the personal histories of the men and women behind the team that enabled and performed the modern medical miracle of the world's first successful organ transplant.

In Good Blood, best-selling writer Julian Guthrie tells the gripping tale of the race to cure a horrible affliction known as Rh disease that stalked families and caused a mother’s immune system to attack her own unborn child. The story is anchored by two very different men on two continents: Dr. John Gorman in New York, who would land on a brilliant yet contrarian idea, and the unassuming Australian whose almost magical blood - and his unyielding devotion to donating it - would save millions of lives.

Stuart Jamieson's story is the story of four decades of advances in heart surgery. Taut, elegantly crafted, and ever-attentive to the patients for whom he was the last best chance, Close to the Sun is an adventurous, riveting account based on the experience of over 40,000 heart surgeries, where everything was on the line every moment in the O.R.

When Dr. David Hosack tilled the country's first botanical garden in the Manhattan soil more than 200 years ago, he didn't just dramatically alter the New York landscape; he left a monumental legacy of advocacy for public health and wide-ranging support for the sciences. In melodic prose, historian Victoria Johnson eloquently chronicles Hosack's tireless career to reveal the breadth of his impact. The result is a lush portrait of the man who gave voice to a new, deeply American understanding of the powers and perils of nature.

Flight for Life is the heart-stopping account of one of the most gripping rescue missions in African history, told by a doctor involved in saving the lives of Nigerian workers who became victims of a tragic American chemical company explosion. Dr. Stewart and his colleague moved mountains and cut red tape to fly patients to one of the premiere burn centers in the United States.

The "absorbing and powerful" (Wall Street Journal) story of two pioneering suffragette doctors who shattered social expectations and transformed modern medicine during World War I. In No Man's Land, Wendy Moore illuminates this turbulent moment of global war and pandemic when women were, for the first time, allowed to operate on men. Their fortitude and brilliance serve as powerful reminders of what women can achieve against all odds.

Caroline Crampton’s life was upended at the age of seventeen, when she was diagnosed with Hodgkin’s lymphoma, a relatively rare blood cancer. After years of invasive treatment, she was finally given the all clear. But being cured of the cancer didn’t mean she felt well. Instead, the fear lingered, and she found herself always on the alert, braced for signs that the illness had reemerged.

Jeanne Marie Laskas first met the young forensic pathologist Dr. Bennet Omalu in 2009, while reporting a story for GQ that would go on to inspire the movie Concussion. Omalu told her about a day in September 2002, when, in a dingy morgue in downtown Pittsburgh, he picked up a scalpel and made a discovery that would rattle America in ways he’d never intended. Omalu was new to America, chasing the dream, a deeply spiritual man escaping the wounds of civil war in Nigeria.

The story of two outsiders and obsessives whose collision prompted an evangelistic alliance on the furthest frontiers of underground music. Steve Davis first met Kavus Torabi - guitarist with Gong, Guapo, Cardiacs and Knifeworld - in the mid-2000s at a gig by French underground rock legends Magma. Over the next few years, this unlikely duo's shared affinity for visionary psychedelic music would become the foundation of not only a firm friendship, but also the most infectiously inclusive broadcasting style since the much-mourned death of John Peel.

Americans are in the midst of a world-historic drug binge. Opiates, amphetamines, benzodiazepines, marijuana, antidepressants, antipsychotics—across the board, consumption has shot up in the twenty-first century. At the same time, the United States is home to the largest prison system in the world, justified in part by a now zombified "war" on drugs. How did we get here?

For nearly three decades, Dr Colin Manock was in charge of South Australia's forensic pathology services. In cases of unexpected or unexplained death, it was his job to determine when a person took their final breath, and whether they had died naturally - or not. But Manock did not have the necessary training for such a specialist role, and made serious errors in several major cases. The full extent of his wrongdoing, and the exact number of cases impacted by it, remain a mystery more than twenty-five years after he retired.

A Silent Spring for the human body, this wide-ranging, genre-crossing literary mystery interweaves the author’s quest to understand the source of her own condition with her telling of the story of the chronically ill 19th-century diarist Alice James—ultimately uncovering the many hidden health hazards of life in America.

Psychedelic drugs are making a comeback. In the mid-20th century, scientists actively studied the potential of drugs like LSD and psilocybin for treating mental health problems. After a decades-long hiatus, researchers are once again testing how effective these drugs are in relieving symptoms for a wide variety of psychiatric conditions, from depression and obsessive-compulsive disorder to posttraumatic stress disorder and substance addiction.

Physician, researcher, and ethics professor Matt McCarthy is on the front lines of a groundbreaking clinical trial testing a new antibiotic to fight lethal superbugs, bacteria that have built up resistance to the life-saving drugs in our rapidly dwindling arsenal. This trial serves as the backdrop for the compulsively listenable Superbugs, and the results will impact nothing less than the future of humanity.

The Aging Revolution is the story of Butler and his disciples: women and men who saw older distressed adults in hospitals and homes, and worse: being ignored by most of the medical establishment. These revolutionaries could not ignore the suffering, and they set out—individually and collectively—to create entirely new ways of caring for aging adults to ease their suffering and improve their quality and length of life.

Ingrassia lost his mother, two sisters, brother, and nephew to cancer—different cancers developing at different points throughout their lives. And while highly unusual, his family is not the only one to wonder whether their heartbreak is the result of unbelievable bad luck, or if there might be another explanation. Through meticulous research and riveting storytelling, Ingrassia takes us from the 1960s—when Dr. Frederick Pei Li and Dr. Joseph Fraumeni Jr. first met, not yet knowing that they would help make a groundbreaking discovery that would affect cancer patients for decades to come.