Medical History

From insulin comas and lobotomy to incarceration and exile, Walter Brown chronicles the troubling history of the diagnosis and (often ineffective) treatment of bipolar disorder through the centuries, before the publication of a groundbreaking research paper in 1949. Cade's "Lithium Salts in the Treatment of Psychotic Excitement" described, for the first time, lithium's astonishing efficacy at both treating and preventing the recurrence of manic-depressive episodes, and would eventually transform the lives of patients, pharmaceutical researchers, and practicing physicians worldwide.

Plagues upon the Earth is a monumental history of humans and their germs. Weaving together a grand narrative of global history with insights from cutting-edge genetics, Kyle Harper explains why humanity’s uniquely dangerous disease pool is rooted deep in our evolutionary past, and why its growth is accelerated by technological progress. He shows that the story of disease is entangled with the history of slavery, colonialism, and capitalism, and reveals the enduring effects of historical plagues all around us, in patterns of wealth, health, power, and inequality.

Intensive care units and mechanical ventilation are the crucial foundation of modern medical care: without them, the appalling death toll of the COVID-19 pandemic would be even higher. In The Autumn Ghost, Dr. Hannah Wunsch traces the origins of these two innovations back to a polio epidemic in the autumn of 1952. Drawing together testimony from doctors, nurses, medical students, and patients, Wunsch relates a gripping tale of an epidemic that changed the world.

Just as polio loomed over the 1950s and AIDS stalked the 1980s and 1990s, post-traumatic stress disorder haunts us in the early years of the 21st century. Over a decade into the United States' "global war on terror", PTSD afflicts as many as 30 percent of the conflict's veterans. But the disorder's reach extends far beyond the armed forces. In total, some 27 million Americans are believed to be PTSD survivors. Yet to many of us, the disorder remains shrouded in mystery, secrecy, and shame.

Galen of Pergamum (A.D. 129-ca. 216) began his remarkable career tending to wounded gladiators in provincial Asia Minor. Later in life he achieved great distinction as one of a small circle of court physicians to the family of Emperor Marcus Aurelius, at the very heart of Roman society. Susan Mattern's The Prince of Medicine offers the first authoritative biography in English of this brilliant, audacious, and profoundly influential figure.

In the quarter century that Victoria Sweet has been a doctor, "health care" has replaced medicine, "providers" (vastly outnumbered by administrators) look at their laptops more than at their patients, and the ruthless pursuit of efficiency has vanquished not only trust and intimacy but also, often, the effectiveness of treatment. Victoria Sweet knows that there is an alternative way, because she has lived and practiced it. In her new book, she reflects with compassion, wit, and profound insight.

On January 12, 2010, a major earthquake struck near Port-au-Prince, Haiti. Hundreds of thousands of people died, and the greater part of the capital was demolished. Dr. Paul Farmer, U.N. deputy special envoy to Haiti, who had worked in the country for nearly thirty years treating infectious diseases like tuberculosis and AIDS, and former President Bill Clinton, the U.N. special envoy to Haiti, had just begun to work on an extensive development plan to improve living conditions in Haiti.

Martin A. Lee traces the dramatic social history of marijuana, from its origins to its emergence in the 1960s as a defining force in a culture war that has never ceased. Lee describes how the illicit marijuana subculture overcame government opposition and morphed into a dynamic, multibillion-dollar industry. Colorful, illuminating, and at times irreverent, this is a fascinating listen for recreational users and patients, students and doctors, musicians and accountants, Baby Boomers and their kids, and anyone who has ever wondered about the secret life of this ubiquitous herb.

For centuries, the human heart seemed beyond our understanding: an inscrutable shuddering mass that was somehow the driver of emotion and the seat of the soul. As cardiologist and best-selling author Sandeep Jauhar tells in The Heart, it was only recently that we demolished age-old taboos and devised the transformative procedures that changed the way we live. Deftly alternating between historical episodes and his own work, Jauhar tells the colorful and little known story of the doctors who risked their careers and the patients who risked their lives to know and heal our most vital organ.

Country of Ash is the starkly compelling, original chronicle of a Jewish doctor who miraculously survived near-certain death, first inside the Lodz and Warsaw ghettoes, where he was forced to treat the Gestapo, then on the Aryan side of Warsaw, where he hid under numerous disguises. He clandestinely recorded the terrible events he witnessed, but his manuscript disappeared during the Warsaw Ghetto Uprising. After the war, reunited with his wife and young daughter, he rewrote his story.

It wasn’t supposed to be this hard. If America could send a man to the moon, shouldn’t the best surgeons in the world be able to build an artificial heart? In Ticker, Texas Monthly executive editor and two time National Magazine Award winner Mimi Swartz shows just how complex and difficult it can be to replicate one of nature’s greatest creations. Part investigative journalism, part medical mystery, Ticker is a dazzling story of modern innovation, recounting 50 years of false starts, abysmal failures, and miraculous triumphs.

In Out Cold, science writer Phil Jaekl chronicles the underappreciated story of human innovation with cold, from Ancient Egypt, where it was used to treat skin irritations, to 18th-century London, where scientists used it in their first explorations of suspended animation. Throughout history, physicians have used cold to innovate life extension, enable distant space missions, and explore consciousness.

From the 15th to the mid-19th centuries, scurvy caused more deaths at sea than storms, shipwrecks, combat, and all other diseases combined. The cure for scurvy ranks among the greatest of military successes, yet its impact on history has mostly been ignored. In this book, Stephen R. Brown delivers a lively recounting of how three determined individuals overcame the constraints of 18th century thinking to solve the greatest medical mystery of their era. Brimming with tales of ships, sailors, and bureaucracy, Brown presents a vivid picture of life aboard the ship during the age of sail.

At the age of 27, married, living in New York, and working in book design, Mary Cregan gives birth to her first child, a daughter she names Anna. But it’s apparent that something is terribly wrong, and two days later, Anna dies - plunging Cregan into suicidal despair. Decades later, sustained by her work, a second marriage, and a son, Cregan reflects on this pivotal experience and attempts to make sense of it. She weaves together literature and research with details from her own ordeal - and the still visible scar of her suicide attempt....

In January 1918, as World War I raged on, a new and terrifying virus began to spread across the globe. In three successive waves, from 1918 to 1919, influenza killed more than 50 million people. German soldiers termed it Blitzkatarrh, British soldiers referred to it as Flanders Grippe, but worldwide, the pandemic gained the notorious title of “Spanish flu”. Nowhere on earth escaped: the United States recorded 550,000 deaths (five times its total military fatalities in the war) while European deaths totaled more than two million.

G. Wayne Miller has dramatically and meticulously reconstructed an amazing true story: how a group of renegade Minnesota surgeons, led by Dr. Walt Lillehei, made medical history by becoming the first doctors to operate deep inside the human heart.

Cystic fibrosis was once a mysterious disease that killed infants and children. Now it could be the key to healing millions with genetic diseases of every type - from Alzheimer's and Parkinson's to diabetes and sickle cell anemia. Told from the perspectives of the patients, families, physicians, scientists, and philanthropists fighting on the front lines, Breath from Salt is a remarkable story of unlikely scientific and medical firsts, of setbacks and successes, and of people who refused to give up hope....

Flight for Life is the heart-stopping account of one of the most gripping rescue missions in African history, told by a doctor involved in saving the lives of Nigerian workers who became victims of a tragic American chemical company explosion. Dr. Stewart and his colleague moved mountains and cut red tape to fly patients to one of the premiere burn centers in the United States.

Based on the film by acclaimed documentary filmmaker Ken Burns, The Mayo Clinic: Faith, Hope, Science chronicles the history of this unique organization, from its roots as an unlikely partnership between a country doctor and a Franciscan order of nuns to its position today as a worldwide model for patient care, research, and education. The book demonstrates how the institution’s remarkable 150-year history continues to inspire the way medicine is practiced there today.

Caroline Crampton’s life was upended at the age of seventeen, when she was diagnosed with Hodgkin’s lymphoma, a relatively rare blood cancer. After years of invasive treatment, she was finally given the all clear. But being cured of the cancer didn’t mean she felt well. Instead, the fear lingered, and she found herself always on the alert, braced for signs that the illness had reemerged.