Medical History

From insulin comas and lobotomy to incarceration and exile, Walter Brown chronicles the troubling history of the diagnosis and (often ineffective) treatment of bipolar disorder through the centuries, before the publication of a groundbreaking research paper in 1949. Cade's "Lithium Salts in the Treatment of Psychotic Excitement" described, for the first time, lithium's astonishing efficacy at both treating and preventing the recurrence of manic-depressive episodes, and would eventually transform the lives of patients, pharmaceutical researchers, and practicing physicians worldwide.

The Great War of 1914-1918 burst on the European scene with a brutality to mankind not yet witnessed by the civilized world. Modern warfare was no longer the stuff of chivalry and honor; it was a mutilative, deadly, and humbling exercise to wipe out the very presence of humanity. Suddenly, thousands upon thousands of maimed, beaten, and bleeding men surged into aid stations and hospitals with injuries unimaginable in their scope and destruction. Doctors scrambled to find some way to salvage not only life but limb.

Intensive care units and mechanical ventilation are the crucial foundation of modern medical care: without them, the appalling death toll of the COVID-19 pandemic would be even higher. In The Autumn Ghost, Dr. Hannah Wunsch traces the origins of these two innovations back to a polio epidemic in the autumn of 1952. Drawing together testimony from doctors, nurses, medical students, and patients, Wunsch relates a gripping tale of an epidemic that changed the world.

Physician, researcher, and ethics professor Matt McCarthy is on the front lines of a groundbreaking clinical trial testing a new antibiotic to fight lethal superbugs, bacteria that have built up resistance to the life-saving drugs in our rapidly dwindling arsenal. This trial serves as the backdrop for the compulsively listenable Superbugs, and the results will impact nothing less than the future of humanity.

It wasn’t supposed to be this hard. If America could send a man to the moon, shouldn’t the best surgeons in the world be able to build an artificial heart? In Ticker, Texas Monthly executive editor and two time National Magazine Award winner Mimi Swartz shows just how complex and difficult it can be to replicate one of nature’s greatest creations. Part investigative journalism, part medical mystery, Ticker is a dazzling story of modern innovation, recounting 50 years of false starts, abysmal failures, and miraculous triumphs.

In 1953, a 27-year-old factory worker named Henry Molaison - who suffered from severe epilepsy - received a radical new version of the then-common lobotomy, targeting the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry was left profoundly amnesic, unable to create long-term memories. Over the next 60 years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.

Author Leslie Lehr wants to talk about boobs. She’s gone from size AA to DDD and everything between, from puberty to motherhood, enhancement to cancer, and beyond. And she’s not alone - these are classic life stages for women today. At turns funny and heartbreaking, A Boob’s Life explores both the joys and hazards inherent to living in a woman’s body. Lehr deftly blends her personal narrative with national history, starting in the 1960s with the women’s liberation movement and moving to the current feminist dialogue and what it means to be a woman.

Jede Krankheit und jeder Mensch haben das Potential, Medizingeschichte zu schreiben. Seit Hunderten von Jahren ergründen Ärzte und Ärztinnen auf der ganzen Welt die Geheimnisse der Medizin, indem sie sich echte Fälle ansehen. Autor und Arzt Roy Benaroch hat für uns spannende Fälle der Medizingeschichte gesammelt, in denen bekannte Persönlichkeiten der Weltgeschichte als mysteriöser Patient oder Patientin vor uns stehen.

As scientists confidently look forward to average life expectancies hitting 100+ years in some Western societies, it’s easy to forget how precarious our grasp on good health has been. It is a struggle no better demonstrated than by the myriad and extraordinary measures that humans have gone to – as diverse as animal sacrifice to stem cell transplants – in their quest to stave off death and disease. Acclaimed historian Mark Jackson takes a fresh global view of mankind’s great battle, exploring both Western and Eastern traditions.

In the quarter century that Victoria Sweet has been a doctor, "health care" has replaced medicine, "providers" (vastly outnumbered by administrators) look at their laptops more than at their patients, and the ruthless pursuit of efficiency has vanquished not only trust and intimacy but also, often, the effectiveness of treatment. Victoria Sweet knows that there is an alternative way, because she has lived and practiced it. In her new book, she reflects with compassion, wit, and profound insight.

In the early 1800s, a century before there was any concept of the gene, physicians in insane asylums began to record causes of madness in their admission books. Almost from the beginning, they pointed to heredity as the most important of these causes. As doctors and state officials steadily lost faith in the capacity of asylum care to stem the terrible increase of insanity, they began emphasizing the need to curb the reproduction of the insane. They became obsessed with identifying weak or tainted families and anticipating the outcomes of their marriages.

More than four hundred abandoned suitcases filled with patients’ belongings were found when Willard Psychiatric Center closed in 1995 after 125 years of operation. They are skillfully examined here and compared to the written record to create a moving—and devastating—group portrait of twentieth-century American psychiatric care.

G. Wayne Miller has dramatically and meticulously reconstructed an amazing true story: how a group of renegade Minnesota surgeons, led by Dr. Walt Lillehei, made medical history by becoming the first doctors to operate deep inside the human heart.

Cystic fibrosis was once a mysterious disease that killed infants and children. Now it could be the key to healing millions with genetic diseases of every type - from Alzheimer's and Parkinson's to diabetes and sickle cell anemia. Told from the perspectives of the patients, families, physicians, scientists, and philanthropists fighting on the front lines, Breath from Salt is a remarkable story of unlikely scientific and medical firsts, of setbacks and successes, and of people who refused to give up hope....

In 1907 Sigmund Freud and Carl Gustav Jung began what promised to be both a momentous collaboration and the deepest friendship of each man's life. Six years later they were bitter antagonists, locked in a savage struggle that was as much personal and emotional as it was theoretical and professional. In between them stood a young woman named Sabina Spielrein, who had been both patient and lover to Jung and colleague and confidante to Freud before going on to become an innovative psychoanalyst herself.

In Origin Story, medical historian Howard Markel recounts the two-year period (1858 to 1860) of Darwin's writing of On the Origin of Species through its spectacular success and controversy. Simultaneously, Markel delves into the mysterious health symptoms Darwin developed, combing the literature to emerge with a cogent diagnosis of a case that has long fascinated medical historians.

Was Andy Warhol a hoarder? Did Einstein have autism? Was Frank Lloyd Wright a narcissist? In this surprising, inventive, and meticulously researched look at the evolution of mental health, acclaimed health and science journalist Claudia Kalb gives listeners a glimpse into the lives of high-profile historic figures through the lens of modern psychology, weaving groundbreaking research into biographical narratives that are deeply embedded in our culture.

In January 1918, as World War I raged on, a new and terrifying virus began to spread across the globe. In three successive waves, from 1918 to 1919, influenza killed more than 50 million people. German soldiers termed it Blitzkatarrh, British soldiers referred to it as Flanders Grippe, but worldwide, the pandemic gained the notorious title of “Spanish flu”. Nowhere on earth escaped: the United States recorded 550,000 deaths (five times its total military fatalities in the war) while European deaths totaled more than two million.

This gripping book traces the evolution of brainwashing from its beginnings in torture and religious conversion into the age of neuroscience and social media. When Pavlov introduced scientific approaches, his research was enthusiastically supported by Lenin and Stalin, setting the stage for major breakthroughs in tools for social, political, and religious control.

Larry Brilliant's life journey has led him on a purposeful path across continents and countercultural movements, marching arm in arm with the men and women who defined a generation. A man who has always been in the right place at the right time, Brilliant has engaged with some of the most prominent thought leaders, spiritual masters, heroes, and icons in the world, including Neem Karoli Baba (Maharajji), Martin Luther King Jr., Steve Jobs, Mikhail Gorbachev, Wavy Gravy, the Grateful Dead, the Dalai Lama, and Barack Obama.