Medical Technology

The United States is embarking on a medical revolution. Supporters of personalized, or precision, medicine—the tailoring of health care to our genomes—have promised to usher in a new era of miracle cures. Advocates of this gene-guided health-care practice foresee a future where skyrocketing costs can be curbed by customization and unjust disparities are vanquished by biomedical breakthroughs. Progress, however, has come slowly, and with a price too high for the average citizen.

In this book, Prusiner tells the remarkable story of his discovery of prions - infectious proteins that replicate and cause disease but surprisingly contain no genetic material - and reveals how superb and meticulous science is actually practiced with talented teams of researchers who persevere. He recounts the frustrations and rewards of years of research and offers fascinating portraits of his peers as they raced to discover the causes of fatal brain diseases.

In this compelling memoir, Jane Hawking relates the inside story of her extraordinary marriage. As Stephen's academic renown soared, his body was collapsing under the assaults of motor neurone disease, and Jane's candid account of trying to balance his 24-hour care with the needs of their growing family is inspirational. This is a book about optimism, love and change that will resonate with listeners everywhere.

The Lobotomist explores one of the darkest chapters of American medicine: the desperate attempt to treat the hundreds of thousands of psychiatric patients in need of help during the middle decades of the 20th century. Into this crisis stepped Walter Freeman, MD, who saw a solution in lobotomy, a brain operation intended to reduce the severity of psychotic symptoms. Drawing on Freeman's documents and interviews with Freeman's family, Jack El-Hai takes a penetrating look at the life and work of this complex scientific genius.

In this partially autobiographical work, best-selling author Lewis Thomas offers insights on subjects as wide-ranging as gender differences, how it feels to be a patient, human vs. computer intelligence, the future of cancer research, and the longevity of the planet—interspersing all with charming anecdotes about his family, his colleagues and himself.

San Francisco's Laguna Honda Hospital is the last almshouse in the country, a descendant of the Hôtel-Dieu (God's hotel) that cared for the sick in the Middle Ages. Ballet dancers and rock musicians, professors and thieves - "anyone who had fallen, or, often, leapt, onto hard times" and needed extended medical care - ended up here. So did Victoria Sweet, who came for two months and stayed for 20 years. Laguna Honda, lower-tech but human-paced, gave Sweet the opportunity to practice a kind of attentive medicine that has almost vanished.

Imagine undergoing an operation without anesthesia performed by a surgeon who refuses to sterilize his tools - or even wash his hands. This was the world of medicine when Thomas Dent Mütter began his trailblazing career as a plastic surgeon in Philadelphia during the middle of the 19th century. Although he died at just 48, Mütter was an audacious medical innovator who pioneered the use of ether as anesthesia, the sterilization of surgical tools, and a compassion-based vision for helping the severely deformed, which clashed spectacularly with the sentiments of his time.

The Headache Godfather traces the life of Seymour Diamond, MD, who was born in 1925, the son of Jewish immigrants from Ukraine and Slovakia, in Chicago, Illinois. Dr. Diamond revolutionized the practice of headache as a medical specialty when he opened the United States' first private headache practice, the Diamond Headache Clinic, in 1974. It quickly became a headache haven for sufferers from around the world.

It wasn’t supposed to be this hard. If America could send a man to the moon, shouldn’t the best surgeons in the world be able to build an artificial heart? In Ticker, Texas Monthly executive editor and two time National Magazine Award winner Mimi Swartz shows just how complex and difficult it can be to replicate one of nature’s greatest creations. Part investigative journalism, part medical mystery, Ticker is a dazzling story of modern innovation, recounting 50 years of false starts, abysmal failures, and miraculous triumphs.

The controversial Emanuel Revici, M.D., made the bones grow back in cancer patients, and restored health to AIDS patients as well as drug addicts and alcoholics. His medicines lifted debilitating migraines in as little as three minutes. Revici's reward? He was attacked and ostracized by the best. JAMA published false reports about his work. The American Cancer Society blasted him time and again. Meanwhile, word of mouth brought new patients to see him for decades.

Lawrence Weschler sets Oliver Sacks' brilliant table talk and extravagant personality in vivid relief, casting himself as a beanpole Sancho to Sacks' capacious Quixote. We see Sacks rowing and ranting and caring deeply; composing the essays that would form The Man Who Mistook His Wife for a Hat; recalling his turbulent drug-fueled younger days; helping his patients and exhausting his friends; and waging intellectual war against a medical and scientific establishment that failed to address his greatest concern: the spontaneous specificity of the individual human soul.

Anyone who has seen a child recover from a wound or a broken bone knows that kids are made to heal. Their bodies are more resilient, more adaptive, and far more able to withstand acute stress than adults'. In this inspiring memoir, Dr. Kurt Newman draws from his long experience as a pediatric surgeon working at one of our nation's top children's hospitals to make the case that children are more than miniature adults.

The Secret Body is a gripping drama of discovery and a landmark account of the dawning revolution in human health that reveals a hitherto invisible universe within each of us.

Dr. Joel Salinas is a Harvard-trained researcher and neurologist with extraordinary gifts that provide him unique access to his patients and enable him to experience life in an extraordinary way. He has mirror-touch synesthesia, a neurological trait that allows him to feel others' emotions and physical sensations. Susceptible to the pain and discomfort of his patients, Salinas uses his heightened empathic ability - what he calls "compulsory mindfulness" - to help understand and better treat their conditions.

Nine million Americans are touched by aneurysms during their lifetimes. This is one story of love. Brainstorm is the candid and powerful memoir of the author's harrowing experience of an aneurysm and his road to recovery. It is a journey of love and devotion and a clash of medical beliefs and countercultures.

An inside account of the fight to contain the world's deadliest diseases - and the panic and corruption that make them worse. The Next Pandemic is a firsthand account of disasters like anthrax, bird flu, and others - and how we could do more to prevent their return. It is both a gripping story of our brushes with fate and an urgent lesson on how we can keep ourselves safe from the inevitable next pandemic.

Salk became a cultural hero and icon for a whole generation. Now, at the fiftieth anniversary of the first national vaccination program, and as humanity is tantalizingly close to eradicating polio worldwide, comes this unforgettable chronicle. Salk's work was an unparalleled achievement, and it makes for a magnificent listen.

In medical school, Paul Farmer found his life’s calling: to cure infectious diseases and to bring the lifesaving tools of modern medicine to those who need them most. Tracy Kidder’s magnificent account shows how one person can make a difference in solving global health problems through a clear-eyed understanding of the interaction of politics, wealth, social systems, and disease. Profound and powerful, Mountains Beyond Mountains takes us from Harvard to Haiti, Peru, Cuba, and Russia.

In the early days of the Cold War, a spirit of desperate scientific rivalry birthed a different kind of space race: not the race to outer space that we all know, but a race to master the inner space of the human body. While surgeons on either side of the Iron Curtain competed to become the first to transplant organs like the kidney and heart, a young American neurosurgeon had an even more ambitious thought: Why not transplant the brain?

Futurologist Luna Lee presents possibilities for the future of medicine in the next 100 years.