Professional Science

Leonardo da Vinci created the two most famous paintings in history, The Last Supper and the Mona Lisa. But in his own mind, he was just as much a man of science and engineering. With a passion that sometimes became obsessive, he pursued innovative studies of anatomy, fossils, birds, the heart, flying machines, botany, geology, and weaponry.

Denis Diderot is often associated with the decades-long battle to bring the world's first comprehensive Encyclopedie into existence. But his most daring writing took place in the shadows. Thrown into prison for his atheism in 1749, Diderot decided to reserve his best books for posterity - for us, in fact. In the astonishing cache of unpublished writings left behind after his death, Diderot challenged virtually all of his century's accepted truths, from the sanctity of monarchy, to the racial justification of the slave trade, to the norms of human sexuality.

In the summer after graduating from college, Suleika Jaouad was preparing, as they say in commencement speeches, to enter “the real world”. She had fallen in love and moved to Paris to pursue her dream of becoming a war correspondent. The real world she found, however, would take her into a very different kind of conflict zone. It started with an itch - first on her feet, then up her legs, like a thousand invisible mosquito bites. Then a trip to the doctor and, a few weeks shy of her 23rd birthday, a diagnosis: leukemia, with a 35 percent chance of survival.

"Are you one of us?" a patient once asked Marsha Linehan, the world-renowned psychologist who developed dialectical behavior therapy. "Because if you were, it would give all of us so much hope." Over the years, DBT had saved the lives of countless people fighting depression and suicidal thoughts, but Linehan had never revealed that her pioneering work was inspired by her own desperate struggles as a young woman. Only when she received this question did she finally decide to tell her story.

Dr. Johnson may have been correct in saying that “Rousseau was a very bad man,” but none can argue that his ideas are among the most influential in all of world history. It was Rousseau, the father of the romantic movement, who was responsible for introducing at least two modern day thoughts that pervade academia. The Confessions is Rousseau’s landmark autobiography. Both brilliant and flawed, it is nonetheless beautifully written and remains one of the most moving human documents in all of literature.

Why we think it’s a great listen: You thought he was a stodgy scientist with funny hair, but Isaacson and Hermann reveal an eloquent, intense, and selfless human being who not only shaped science with his theories, but politics and world events in the 20th century as well. Based on the newly released personal letters of Albert Einstein, Walter Isaacson explores how an imaginative, impertinent patent clerk became the mind reader of the creator of the cosmos.

The bestselling author of Leonardo da Vinci and Steve Jobs returns with a “compelling” (The Washington Post) account of how Nobel Prize winner Jennifer Doudna and her colleagues launched a revolution that will allow us to cure diseases, fend off viruses, and have healthier babies.

Part memoir, part history, Burn Book is a necessary chronicle of tech’s most powerful players. This is the inside story we’ve all been waiting for about modern Silicon Valley and the biggest boom in wealth creation in the history of the world. When tech titans crowed that they would “move fast and break things,” Kara Swisher was moving faster and breaking news. While covering the explosion of the digital sector in the early 1990s, she developed a long track record of digging up and reporting the facts about this new world order.

What does it mean to explore and confront the unknown? Beyond the Trees recounts Adam Shoalts's epic, never-before-attempted solo crossing of Canada's mainland Arctic in a single season. It's also a multilayered story that weaves the narrative of Shoalts's journey into accounts of other adventurers, explorers, First Nations, fur traders, dreamers, eccentrics, and bush pilots to create an unforgettable tale of adventure and exploration.

In September 1838, a young Englishman named Charles Darwin hit upon the idea that "natural selection" among competing individuals would lead to wondrous adaptations and species diversity. Twenty-one years passed between that epiphany and publication of On the Origin of Species. The human drama and scientific controversy of that time constitute a fascinating, tangled tale that illuminates this cautious naturalist who sparked an intellectual revolution.

Thousands of people have had near-death experiences, but scientists have argued that they are impossible. Dr. Eben Alexander was one of those scientists. A highly trained neurosurgeon, Alexander knew that NDEs feel real, but are simply fantasies produced by brains under extreme stress. Then, Dr. Alexander’s own brain was attacked by a rare illness. The part of the brain that controls thought and emotion—and in essence makes us human—shut down completely. For seven days he lay in a coma. Then, as his doctors considered stopping treatment, Alexander’s eyes popped open. He had come back.

Explorer, diving pioneer, filmmaker, inventor, and activist, Jacques Cousteau was blessed from his childhood with boundless curiosity about the natural world. As the leader of fascinating, often dangerous expeditions all over the planet, he discovered firsthand the complexity and beauty of life on earth and undersea - and watched the toll taken by human activity in the 20th century.

Clarence Darrow is the lawyer every law school student dreams of being: on the side of right, loved by many women, played by Spencer Tracy in Inherit the Wind. His days-long closing arguments delivered without notes won miraculous reprieves for men doomed to hang.

Pulitzer Prize winner Wallace Stegner recounts the remarkable career of Major John Wesley Powell, the distinguished ethnologist and geologist who explored the Colorado River, the Grand Canyon, and the homeland of the Southwest Indian tribes. This classic work is a penetrating and insightful study of the Powell’s career, from the beginning of the Powell Survey, in which Powell and his men famously became the first to descend the Colorado River, to his eventual expulsion from the Geological Survey.

When Michael Pollan set out to research how LSD and psilocybin (the active ingredient in magic mushrooms) are being used to provide relief to people suffering from difficult-to-treat conditions such as depression, addiction, and anxiety, he did not intend to write what is undoubtedly his most personal book. But upon discovering how these remarkable substances are improving the lives not only of the mentally ill but also of healthy people coming to grips with the challenges of everyday life, he decided to explore the landscape of the mind in the first person as well as the third.

In Prince of Darkness, a groundbreaking and vivid account, eminent historian Shane White reveals the larger-than-life story of a man who defied every convention of his time. He wheeled and dealed in the lily-white business world, he married a White woman, he bought a mansion in rural New Jersey, he owned railroad stock on trains he was not legally allowed to ride, and generally he set his White contemporaries' teeth on edge when he wasn't just plain outsmarting them.

The search to find medicines is as old as disease, which is to say as old as the human race. Through serendipity - by chewing, brewing, and snorting - some Neolithic souls discovered opium, alcohol, snakeroot, juniper, frankincense, and other helpful substances. Ötzi the Iceman, the 5,000-year-old hunter frozen in the Italian Alps, was found to have whipworms in his intestines and Bronze Age medicine, a worm-killing birch fungus, knotted to his leggings.

How big is the universe? In the early twentieth century, scientists took sides. One held that the entire universe was contained in the Milky Way galaxy. Their champion was the strong-willed astronomer Harlow Shapley. Another camp believed that the universe was so vast that the Milky Way was just one galaxy among billions—the view that would prevail, proven by the equally headstrong Edwin Hubble.

In this partially autobiographical work, best-selling author Lewis Thomas offers insights on subjects as wide-ranging as gender differences, how it feels to be a patient, human vs. computer intelligence, the future of cancer research, and the longevity of the planet—interspersing all with charming anecdotes about his family, his colleagues and himself.

In 1911, some of the greatest minds in science convened at the First Solvay Conference in Physics, a meeting like no other. Almost half of the attendees had won or would go on to win the Nobel Prize. Over the course of those few days, these minds began to realize that classical physics was about to give way to quantum theory, a seismic shift in our history and how we understand not just our world, but the universe.