Systems Science

What do obesity, insulin resistance, diabetes, fatty liver disease, hypertension, cardiovascular disease, stroke, neurological disorders, and premature death have in common? All can be stoked by high uric acid levels. Our most respected scientific literature is bursting with evidence that elevated uric acid levels lie at the root of many pervasive health conditions, but mainstream medicine for the most part remains unaware of this connection.

Donors, leaders of nonprofits, and public policy makers usually have the best of intentions to serve society and improve social conditions. But often their solutions fall far short of what they want to accomplish and what is truly needed. Moreover, the answers they propose and fund often produce the opposite of what they want over time. We end up with temporary shelters that increase homelessness, drug busts that increase drug-related crime, or food aid that increases starvation.

Dive into the captivating world of Frank Herbert beyond Dune with this immersive audiobook edition of 'Missing Link.' A brilliant exploration of humanity's evolution and potential, Herbert's masterful novella challenges listeners with profound questions about our species' future. Follow the expedition of Lewis Orne as he investigates an emerging civilization that may hold the key to mankind's next evolutionary step.

Modern medical science has finally caught up to what traditional healing systems have known for centuries. Many traditional healing techniques and medicines are often assumed to be archaic, outdated, or unscientific compared to modern Western medicine. Nicole Redvers, a naturopathic physician and member of the Deninu K'ue First Nation, analyzes modern Western medical practices using evidence-informed Indigenous healing practices and traditions from around the world - from sweat lodges and fermented foods to Ayurvedic doshas and meditation.

After saying goodbye to his life on earth, he never expected to find a brand new world still awaiting for him. One where immortals flew through the clouds and ancient evils hid below the surface. One where fables, myths, and legends filled every corner. One where he could finally start anew. Now, however, John is about to learn a valuable lesson, for any place humanity rules will always be the same - a domain where sin and ambition can only be tamed by power. Will he have the strength to walk this road on his own or will he be unable to heal the old wounds hidden deep within his heart?

Savannah was unlike any city Derek had ever been to. For the first time since his arrival in Cydaria, Derek actually met a respectable city lord. Natalie Savannah and the city she ruled were much more than he’d imagined. With this combination, Derek made the decision to put down roots by building a shop from scratch and moving his people in. He was even able to get Silvi the beloved kitchen that she so desired, along with personally meeting Alanah Swan and learning new things about the new system he was thrown into—things that only someone who was truly strong would know.

Since 1980, the number of people in US prisons has increased more than 450 percent. Despite a crime rate that has been falling steadily for decades, California has led the way in this explosion, with what a state analyst called "the biggest prison building project in the history of the world". Golden Gulag provides the first detailed explanation for that buildup by looking at how political and economic forces conjoined to produce the prison boom.

A magnificently reported and soulfully crafted exploration of the human immune system - the key to health and wellness, life and death. An epic, first-of-its-kind audiobook, entwining leading-edge scientific discovery with the intimate stories of four individual lives, by the Pulitzer Prize-winning New York Times journalist.

A decade ago, developers built information-sharing software by writing a lot of custom code in a single code base, then adding layers of caching. Now we build information systems: interdependent software and services, data platforms, and event streams. Many of our software-to-systems initiatives fail, though, and when they do, we double down on traditional linear approaches. But linear thinking cannot resolve systems challenges. We need to shift to systems thinking.

We all know that life in prison ain't grand, but the utter horror of it springs from the pages of this autobiography, written by a one-time death-row inmate. Billy Wayne Sinclair is now serving a reduced 90-year sentence for murdering a Baton Rouge convenience store owner in a robbery gone wrong more than three decades ago. His story of an adult life spent in one of Louisiana's harshest prisons is amazing, not only because he has survived with his soul intact, but because it provides such a raw look at the inner workings of a system bent on revenge, not rehabilitation.

You wake up and feel a tickle in your throat. Your head hurts. You’re mildly annoyed as you get the kids ready for school and dress for work yourself. Meanwhile, an epic war is being fought, just below your skin. Millions are fighting and dying for you to be able to complain as you head out the door. So what, exactly, is your immune system? In Immune, Philipp Dettmer, the brains behind the most popular science channel on YouTube, takes listeners on a journey through the fortress of the human body and its defenses.

How does blood circulate throughout your body? How does your brain make your body move? This series explores the many systems at work in the human body. Young listeners will learn how each system works, the parts of each system, how the systems work together, and how to keep each system healthy. This volume includes The Circulatory System, The Digestive System, and The Muscular System.

Uncover the historical and social roots of caste discrimination in Who Were the Shudras? by Dr. B. R. Ambedkar. This groundbreaking work challenges the traditional narratives of Hindu society, offering a meticulous examination of the origins and status of the Shudra caste. Ambedkar's critical analysis and visionary insights call for a re-evaluation of social hierarchies and advocate for equality and justice.

She wanted to be a Necromancer, but awakened as a Saint! Somehow her summoned heroes are all undead? How will the church react when their Saintess summons a skeleton in place of a mighty hero? Sofia isn’t too keen on finding out. In this world, Gods choose [Saints], and [Saints] summon [Heroes] from other worlds; everyone knows that. But Sofia had a thing for bones ever since she was a child; there’s only one [Class] she wants: [Necromancer]! When, by the whims of fate, she gets both classes at the same time, the system breaks.

In just seven days, the world will crumble. The System's Descent will usher in a new era of chaos: wild animals mutating, monstrous creatures emerging, and the cessation of modern technology. Humanity will be left defenseless. Drew Wright knows none of this. At least not until he is rudely ripped from his bed and thrust into a white room to undergo a taser-happy ‘Tutorial’. Turns out, he is one of a thousand randomly selected people to be forewarned of the approaching apocalypse. Now, he faces the delightful task of convincing his wife and mother of the devastation hurtling towards them.

Jeb Trapper tried to kill himself. The gun jammed. Two months later, the vet is now participating in underground trials of ecstasy to treat his PTSD. Everything seems to be going great until Jeb is teleported into a tutorial, along with everyone else on Earth. Now, he has to choose the level of difficulty. There's just one problem: He's high as a kite, and nothing seems impossible.

In a rare blend of scientific insight and writing as elegant as the theories it explains, Brian Greene, one of the world's leading string theorists, peels away the layers of mystery surrounding string theory to reveal a universe that consists of 11 dimensions where the fabric of space tears and repairs itself, and all matter-from the smallest quarks to the most gargantuan supernovas-is generated by the vibrations of microscopically tiny loops of energy.

A leading expert in epigenetics - how genes switch on and off - provides a revolutionary, holistic, and personalized approach to better health by improving how your genes behave to prevent and reverse common ailments, chronic illnesses, and life-threatening diseases, including cardiovascular disease, autoimmune disorders, anxiety, depression, digestive issues, obesity, cancer, diabetes, and more.

Living with an advanced Werewolf System hasn't always been easy for Gary Dem. But it sure comes in handy. Without it, he would never have been able to take on—and literally devour—a lethal Altered and live to tell about it. With his new rank and abilities, Gary and his gang, the Howlers, are primed to finally wipe out the last remaining competition in Slough. As long as he can control himself and his growing werewolf pack, things might just turn out all right . . . But it's not bloody likely.

Now the site of EBO’s first completed Red Cathedral, the Onyx Delta has become the center of the virtual world, and the entire player base is descending on Ned’s city to try their hand at the fearsome new raid and reap the game-changing rewards within. At the same time, a powerful, menacing guild is running roughshod over the western continents, razing every city in their wake and winning Frank’s obnoxiously loud approval from afar. But Ned knows that it’s only a matter of time before their forces sail east to the delta and attempt to burn down everything he’s built.