The people who call End of the Line need hope. They need reassurance that life is worth living. But some are unlucky enough to get through to Laura. Laura doesn’t want them to hope. She wants them to die. Laura hasn’t had it easy: she's survived sickness and a difficult marriage only to find herself heading for forty, unsettled and angry. She doesn't love talking to people worse off than she is. She craves it. But now someone’s on to her - Ryan, whose world falls apart when his pregnant wife ends her life, hand in hand with a stranger.

It is midnight on the morning of Halloween, and Jen anxiously waits up for her 18-year-old son, Todd, to return home. But worries about his broken curfew transform into something much more dangerous when Todd finally emerges from the darkness. As Jen watches through the window, she sees her funny, seemingly happy teenage son stab a total stranger.

Charlotte has an unsavory past, but she’s on the straight and narrow these days. She was so young then—she married the wrong man, falling for Sam’s sweet-talking charm and charisma, and got caught up in his con artist games. Now Sam is missing. But before he disappeared, he left urgent, cryptic messages about someone threatening him—someone who has been threatening Charlotte, too. So Charlotte takes a job as a personal assistant for an engagement party aboard a private luxury cruise ship, the Cleobella, to get far away from anyone who means her harm.

Joan has spent a lifetime enduring the cruelties of men. But when one of them commits a shocking act of violence in front of her, she flees New York City in search of Alice, the only person alive who can help her make sense of her past. In the sweltering hills above Los Angeles, Joan unravels the horrific event she witnessed as a child - that has haunted her every waking moment - while forging the power to finally strike back.

Born in 1905, Daisy Goodwill Flett drifts through the chapters of childhood, marriage, widowhood, remarriage, motherhood, and old age, bewildered by her inability to understand her own role in the unsettled decades of the twentieth century. At last, reflecting on her unobserved and unconventional life, Daisy attempts to find a way to tell her story within a novel that is itself about the limitations of autobiography.