Emma Colton left her life behind when she moved from Chicago to San Francisco. She has a new job at the Health Department, a tiny apartment, and has dealt with being unlucky in love for most of her adult life. She’s hoping a new city and a fresh outlook will help her find the woman she’s been waiting for.

Julianna Bristol is on the brink of success as her fledgling video game design company goes after the opportunity of a lifetime. But her ex-husband is intent on making her fodder for late-night comedy. When she unexpectedly gains custody of her nine-year-old niece, everything in Julianna's exquisitely planned life changes in the blink of an eye.

Elle Robinson's world is literally swept away when a raging flood sends her car careening toward certain doom, only to be rescued by Angela Lane – a spirited, self-reliant, and unexpected savior who pulls Elle back from the edge of calamity. In the aftermath of their brush with mortality, passions ignite between the two women, mirroring the uncontrollable rise of the floodwaters. However, fate has a wicked sense of humor.

Ellie Fisher loves most things about being a nurse in the emergency department . . . just not working with Regina Novak, an icy attending physician who acts as if she's God's gift to medicine. The dislike is completely mutual. Regina thinks Ellie is a starry-eyed romantic with a sentimental attitude that has no place at work. When Regina gets talked into volunteering at a singles auction, Ellie accidentally bids on her—and ends up winning. Oops! Since the money raised is for a good cause, they reluctantly decide to go through with the dates.

Since A-List actress and Hollywood's sweetheart Wren Acker came out, not only is she at the top of the acting world; she's also crush number one for her queer fanbase. Loving life, loving her job, loving her cat-everything is fantastic. Except that lack of any kind of private life. When a car accident brings her to the ER, the bottom falls out of her world when she realizes that reserved Doctor Taylor, her physician, is Madison Taylor from camp way back when she was a kid. And boy, does Madison still hold a well-earned grudge for how that all ended.