The Inquisition moves amongst mankind like an avenging shadow, striking down the enemies of humanity with uncompromising ruthlessness. When he finally corners an old foe, Inquisitor Gregor Eisenhorn is drawn into a sinister conspiracy. As events unfold and he gathers allies - and enemies - Eisenhorn faces a vast interstellar cabal and the dark power of daemons, all racing to recover an arcane text of abominable power: an ancient tome known as the Necroteuch.

Sister Adamanthea is an oddity among the Adepta Sororitas - a Sister Repentia who has been cleansed of her sin and returned to her duty, rather than finding penance in death. Seen by the faithful as a living miracle, she herself is unsure. Still feeling the weight of her crime, she wonders if she belongs in the sisterhood at all. When she is forced to appear with a famed priest on a most holy day, Adamanthea's doubts itensify...until disaster strikes.

When his body is hideously damaged in an enemy attack, it looks as though Inquisitor Gideon Ravenor's promising career would be abruptly brought short. Now, encased in a life support sytem that keeps him alive but forever cuts him off from the physical world, Ravenor utilises his formidable mental powers to continue his investigations. Along with his retinue of warriors and assassins, Gideon Ravenor fights to protect an Imperium he can no longer see, hear or feel.

In the hellish sprawl of Imperial Terra, Ordo Hereticus Inquisitor Erasmus Crowl serves as a stalwart protector, for even the Throneworld is not immune to the predations of its enemies. In the course of his duty, Crowl becomes embroiled in a dark conspiracy, one that leads all the way to the halls of the Imperial Palace. As he plunges deeper into the shadowy underbelly of the many palace districts, his investigation attracts the attention of hidden forces, and soon he and his acolyte Spinoza are being hunted.

Exile to the miserable world of Sedh, the disgraced Necron Lord Oltyx is consumed with bitterness. Once heir to the throne of a dynasty, he now commands nothing but a dwindling garrison of warriors, in a never-ending struggle against Ork invaders. Oltyx can think of nothing but the prospect of vengeance against his betrayers, and the reclamation of his birthright. But the Orks are merely the harbingers of a truly unstoppable force. Unless Oltyx acts to save his dynasty, revenge will win him only ashes.