When it comes to optimizing our entire biological systems from the ground up, where do we start? This week, Dr. Scott Sherr introduces Health Optimization Medicine, a groundbreaking clinical framework targeting cellular and gut health to restore our bodies to their optimal state. He shares how modern tests can guide personalized, data-driven interventions, and why most people are missing this foundation in both traditional and functional medicine. Whether you're a biohacker or a health practitioner, this conversation offers a completely new perspective on longevity, resilience, and feeling your best.

How long will you live? Take our quiz today to find out at ageist.com/longevity-quiz!

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Timeline Nutrition: Our favorite supplement for cell support and mitochondrial function. Listeners can now get 20% off their first Timeline purchase by using the code “AGEIST” at checkout at TimelineNutrition.com/ageist.

LMNT Electrolytes: Our #1 electrolytes for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

Our Place: Right now, Our Place is having their biggest sale of the New Year! Save up to 35% sitewide. Head to fromourplace.com/ageist and see why more than a million people have made the switch to Our Place kitchenware. And with their 100-day risk-free trial, free shipping, and free returns, you can shop with total confidence. Shop the Our Place Holiday Sale right now (no code needed).

Key Moments
“There's no specialty out there that's trying to keep you healthy, to optimize your health, to find the root causes of your health.”

“If your gut is not optimized, you're not gonna be optimized no matter what you try.”

“The beneficial side effect of optimizing your health is that everything else will likely improve as well.”

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Michel May, founder of Aizome and expert in nontoxic textiles, joins us to unpack the hidden health hazards in our bedding. He explains how synthetic dyes and petrochemical-based textiles may be impacting our health, particularly our skin microbiome and immune system. Michel walks us through the lack of regulation in the textile industry and how misleading labeling allows harmful substances into our homes. He also shares his take on choosing healthier bedding materials, including why natural, unbleached fabrics are the safest bet for everyday use.

How long will you live? Take our quiz today to find out at ageist.com/longevity-quiz!

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Maui Nui Venison: The cleanest, most nutrient-dense red meat out there—high in protein, rich in antioxidants, and ethically harvested. And once a year, they release something truly special: The Reserve Holiday Roast. A 14-day aged, center-cut venison roast made from 100% wild-harvested Axis deer on Maui—naturally lean, deeply flavorful, and remarkably easy to prepare. It’s a celebration of the season, of connection, and of the values we share: bringing something rare, responsible, and meaningful to the table. Just go to mauinuivenison.com/ageist to get your Holiday Roast. It ships frozen, directly to your door, nationwide. There are only 500 roasts available, so once they’re gone, they’re gone until next year.

LMNT Electrolytes: Our #1 electrolytes for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

Timeline Nutrition: Our favorite supplement for cell support and mitochondrial function. Listeners can now get 20% off their first Timeline purchase by using the code “AGEIST” at checkout at TimelineNutrition.com/ageist.

Key Moments

“Fibers are an extension of your body.”

“There are no super smart people with big hats that approved these things after rigorous testing.”

“Most house dust is from textiles.”

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Aizome

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Dr. Ella Faktorovich joins us to unpack the latest advances in laser vision correction and lens implant surgery. She breaks down what makes these procedures safer and more effective than ever, and who stands to benefit most. We explore the life-changing impact that improved vision can have on vitality, independence, and mental clarity, especially for those over 40. Whether you’re tired of glasses, struggling with contact lenses, or curious about new options, this episode will show you how to reclaim your “pep” through vision.

How long will you live? Take our quiz today to find out at ageist.com/longevity-quiz!

Special Thanks to Our Sponsors

Timeline Nutrition: Our favorite supplement for cell support and mitochondrial function. Listeners can now get 20% off their first Timeline purchase by using the code “AGEIST” at checkout at TimelineNutrition.com/ageist.

LMNT Electrolytes: Our #1 electrolytes for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

Maui Nui Venison: The cleanest, most nutrient-dense red meat out there—high in protein, rich in antioxidants, and ethically harvested. And once a year, they release something truly special: The Reserve Holiday Roast. A 14-day aged, center-cut venison roast made from 100% wild-harvested Axis deer on Maui—naturally lean, deeply flavorful, and remarkably easy to prepare. It’s a celebration of the season, of connection, and of the values we share: bringing something rare, responsible, and meaningful to the table. Just go to mauinuivenison.com/ageist to get your Holiday Roast. It ships frozen, directly to your door, nationwide. There are only 500 roasts available, so once they’re gone, they’re gone until next year.

Key Moments

“This is probably one of the safest procedures we have in the whole field of medicine.”

“It’s a procedure that you grow into, as one of my patients said.”

“I got my pep back—that’s what a patient told me after cataract surgery.”

Connect with Dr. Ella

Pacific Vision Institute

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Dr. Brendan Murray shares insights from decades of experience treating elite athletes and everyday patients alike. He explains why poor movement mechanics, not aging, are the real cause of most joint pain and physical decline. Listeners will learn how to recognize faulty compensation patterns, understand the difference between stimulation and irritation in recovery, and create training plans that build resilience without injury. Brendan makes the case for personalized movement correction as the key to physical longevity.

How long will you live? Take our quiz today to find out at ageist.com/longevity-quiz!

Special Thanks to Our Sponsors

Maui Nui Venison: The cleanest, most nutrient-dense red meat out there—high in protein, rich in antioxidants, and ethically harvested. And once a year, they release something truly special: The Reserve Holiday Roast. A 14-day aged, center-cut venison roast made from 100% wild-harvested Axis deer on Maui—naturally lean, deeply flavorful, and remarkably easy to prepare. It’s a celebration of the season, of connection, and of the values we share: bringing something rare, responsible, and meaningful to the table. Just go to mauinuivenison.com/ageist to get your Holiday Roast. It ships frozen, directly to your door, nationwide. There are only 500 roasts available, so once they’re gone, they’re gone until next year.

LMNT Electrolytes: Our #1 electrolytes for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

Timeline Nutrition: Our favorite supplement for cell support and mitochondrial function. Listeners can now get 20% off their first Timeline purchase by using the code “AGEIST” at checkout at TimelineNutrition.com/ageist.

Key Moments
“Pain is not normal. Arthritis is common, but it’s not normal.”

“The adaptation is predicting the next injury.”

“Fatigue leads to neurological failure.”

Connect with Dr. Murray
Canyon Ranch Longevity8

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Click Here for the full interview transcript.

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Eric Williamson, PhD, registered dietitian and Director of Nutrition at Canyon Ranch, lays out a clear, practical roadmap for building a better relationship with food. For starters, he explains why one-size-fits-all advice around protein, fiber, and fat often misses the mark. Learn how to optimize your diet without stress, fear, or gimmicks, especially as you age. From fiber-rich meals to evidence-based takes on seed oils and sweeteners, Eric offers straight answers rooted in science, not trends.

How long will you live? Take our quiz today to find out!

Special Thanks to Our Sponsors

Timeline Nutrition: Our favorite supplement for cell support and mitochondrial function. Listeners can now get 20% off their first Timeline purchase by using the code “AGEIST” at checkout at TimelineNutrition.com/ageist.

LMNT Electrolytes: Our #1 electrolytes for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

Our Place: Right now, Our Place is having their biggest sale of the year! Save up to 35% sitewide now through December 2nd. Head to fromourplace.com and see why more than a million people have made the switch to Our Place kitchenware. And with their 100-day risk-free trial, free shipping, and free returns, you can shop with total confidence. Shop the Our Place Black Friday Sale right now (no code needed).

Key Moments

“Protein is the nutrient that we have the highest needs for next to water.”

“Fiber is the only nutrient where we don’t see an upper limit for disease risk reduction.”

“Instead of being scared of our grocery store aisles, we’re better served by focusing on what to eat.”

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Canyon Ranch

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Dr. Suzanne Gilberg is shifting the menopause conversation with science, compassion, and boldness. In this re-airing of one of our favorite episodes, she addresses common fears about hormone replacement therapy (HRT), especially the perceived connection to breast cancer, and unpacks what current data really shows. She also emphasizes the importance of keeping an open mind as science evolves and shares what excites her most about women’s health and aging today. All in all, Dr. Suzanne’s perspective encourages listeners to rethink how we define health, longevity, and female vitality in midlife and beyond.

How long will you live? Take our quiz today to find out at ageist.com/longevity-quiz!

Special Thanks to Our Sponsors

fatty15: C15:0 is the first essential fatty acid to be discovered in over 90 years, and fatty15 is on a mission to optimize your C15:0 levels to help support your long-term health and wellness—especially as you age. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/AGEIST and using the code “AGEIST” at checkout.

Our Place: The top cookware brand for non-toxic, PFA-free pots and pans. Make the switch today. Plus, Our Place is having their biggest sale of the year right now! Save up to 35% sitewide now through January 12th. Head to fromourplace.com/AGEIST to see why more than a million people have made the switch to Our Place kitchenware.

Maui Nui: The cleanest, most nutrient-dense red meat out there—high in protein, rich in antioxidants, and ethically harvested. Their new, subscription-only ‘Ohana Reserve Aged Cuts are aged for 14 days to make for unforgettable flavor, plus their to-go venison sticks are perfect for healthy snacking. Right now, Maui Nui is offering a free 12-pack of their jerky sticks with your first order of $79 or more. Just go to mauinuivenison.com/ageist to grab yours.

Key Moments

“Science is not a religion. It is not a monolith, it is not unchanging and unmoving. That is not what science is. Science is a process of inquiry. Period. End of sentence.”

“There’s actually quite a bit of data on the potential health benefits of estrogen specifically in all of us and in breast cancer survivors.”

“This is not a disease; this is a state of being alive. So you have options in terms of how you want to live and age well, whatever that means to you.”

Connect with Dr. Gilberg
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Click Here for the full interview transcript.

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Mike Siemens, Director of Performance Science at Canyon Ranch, explains how performance science helps people train for what really matters—from lifting a suitcase to hiking at 90. He breaks down the importance of VO2 max, zone 2 training, and strength work, particularly for those over 50. Mike offers clear, actionable strategies for balancing recovery, building functional strength, and staying consistent. This is a highly informative episode for anyone who wants to age with power, purpose, and precision.

How long will you live? Take our quiz today to find out at ageist.com/longevity-quiz!

Special Thanks to Our Sponsors
LMNT Electrolytes: Our #1 electrolytes for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

Our Place: The top cookware brand for non-toxic, PFA-free pots and pans. Make the switch today. Plus, Our Place is having their biggest sale of the year right now! Save up to 35% sitewide now through January 12th. Head to fromourplace.com/AGEIST to see why more than a million people have made the switch to Our Place kitchenware.

Maui Nui: The cleanest, most nutrient-dense red meat out there—high in protein, rich in antioxidants, and ethically harvested. Their new, subscription-only ‘Ohana Reserve Aged Cuts are aged for 14 days to make for unforgettable flavor, plus their to-go venison sticks are perfect for healthy snacking. Right now, Maui Nui is offering a free 12-pack of their jerky sticks with your first order of $79 or more. Just go to mauinuivenison.com/ageist to grab yours.

Key Moments

"Be an exercise participant, not an exercise perfectionist."

"VO2 max is your aerobic horsepower—your body's ability to bring oxygen to your muscles."

"If you want to age in a healthy way, you've got to lift weights. End of story, full stop."

Connect with Mike Siemens
Join David and Mike at Super Age x Canyon Ranch Longevity8

Canyon Ranch Tuscon

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Amy Hawthorne, director of mental health and wellness at Canyon Ranch, joins us on The AGEIST Podcast to talk about the real drivers of change, and why simply knowing what to do often isn’t enough. She explains how shame, trauma, and outdated emotional tools shape our habits and relationships, especially as we age. Amy introduces self-compassion as an essential tool, not a luxury, for building resilience and long-term health. Take a pause, tune in, and walk away from this conversation knowing how to better understand your emotional blueprint and start creating sustainable change in your life.

How long will you live? Take our quiz today to find out at ageist.com/longevity-quiz!

Special Thanks to Our Sponsors

Maui Nui: The cleanest, most nutrient-dense red meat out there—high in protein, rich in antioxidants, and ethically harvested. Their new, subscription-only ‘Ohana Reserve Aged Cuts are aged for 14 days to make for unforgettable flavor, plus their to-go venison sticks are perfect for healthy snacking. Right now, Maui Nui is offering a FREE 12-pack of their snack sticks with your first order of $79 or more. Just go to mauinuivenison.com/ageist to grab yours.

LMNT Electrolytes: Our #1 electrolytes for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

fatty15: C15:0 is the first essential fatty acid to be discovered in over 90 years, and fatty15 is on a mission to optimize your C15:0 levels to help support your long-term health and wellness—especially as you age. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/AGEIST and using the code “AGEIST” at checkout.

Key Moments

“Self-compassion is not a luxury, but it's an absolute necessity.”

“We pick people with whom we can suffer in a familiar way.”
“You have never regretted pausing when you're agitated.”

Connect with Amy Hawthorne
Canyon Ranch on Instagram

Join David and Amy at Super Age x Canyon Ranch Longevity8

Connect with AGEIST

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Click Here for the full interview transcript.

Say hi to the AGEIST team!