Mike Siemens, Director of Performance Science at Canyon Ranch, explains how performance science helps people train for what really matters—from lifting a suitcase to hiking at 90. He breaks down the importance of VO2 max, zone 2 training, and strength work, particularly for those over 50. Mike offers clear, actionable strategies for balancing recovery, building functional strength, and staying consistent. This is a highly informative episode for anyone who wants to age with power, purpose, and precision.

How long will you live? Take our quiz today to find out at ageist.com/longevity-quiz!

Special Thanks to Our Sponsors
LMNT Electrolytes: Our #1 electrolytes for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

Our Place: The top cookware brand for non-toxic, PFA-free pots and pans. Make the switch today. Plus, Our Place is having their biggest sale of the year right now! Save up to 35% sitewide now through January 12th. Head to fromourplace.com/AGEIST to see why more than a million people have made the switch to Our Place kitchenware.

Maui Nui: The cleanest, most nutrient-dense red meat out there—high in protein, rich in antioxidants, and ethically harvested. Their new, subscription-only ‘Ohana Reserve Aged Cuts are aged for 14 days to make for unforgettable flavor, plus their to-go venison sticks are perfect for healthy snacking. Right now, Maui Nui is offering a free 12-pack of their jerky sticks with your first order of $79 or more. Just go to mauinuivenison.com/ageist to grab yours.

Key Moments

"Be an exercise participant, not an exercise perfectionist."

"VO2 max is your aerobic horsepower—your body's ability to bring oxygen to your muscles."

"If you want to age in a healthy way, you've got to lift weights. End of story, full stop."

Connect with Mike Siemens
Join David and Mike at Super Age x Canyon Ranch Longevity8

Canyon Ranch Tuscon

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Amy Hawthorne, director of mental health and wellness at Canyon Ranch, joins us on The AGEIST Podcast to talk about the real drivers of change, and why simply knowing what to do often isn’t enough. She explains how shame, trauma, and outdated emotional tools shape our habits and relationships, especially as we age. Amy introduces self-compassion as an essential tool, not a luxury, for building resilience and long-term health. Take a pause, tune in, and walk away from this conversation knowing how to better understand your emotional blueprint and start creating sustainable change in your life.

How long will you live? Take our quiz today to find out at ageist.com/longevity-quiz!

Special Thanks to Our Sponsors

Maui Nui: The cleanest, most nutrient-dense red meat out there—high in protein, rich in antioxidants, and ethically harvested. Their new, subscription-only ‘Ohana Reserve Aged Cuts are aged for 14 days to make for unforgettable flavor, plus their to-go venison sticks are perfect for healthy snacking. Right now, Maui Nui is offering a FREE 12-pack of their snack sticks with your first order of $79 or more. Just go to mauinuivenison.com/ageist to grab yours.

LMNT Electrolytes: Our #1 electrolytes for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

fatty15: C15:0 is the first essential fatty acid to be discovered in over 90 years, and fatty15 is on a mission to optimize your C15:0 levels to help support your long-term health and wellness—especially as you age. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/AGEIST and using the code “AGEIST” at checkout.

Key Moments

“Self-compassion is not a luxury, but it's an absolute necessity.”

“We pick people with whom we can suffer in a familiar way.”
“You have never regretted pausing when you're agitated.”

Connect with Amy Hawthorne
Canyon Ranch on Instagram

Join David and Amy at Super Age x Canyon Ranch Longevity8

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Click Here for the full interview transcript.

Say hi to the AGEIST team!

What happens when you reach the pinnacle of business success—and feel completely trapped? We invited one of our recent featured profiles, Mark Rampolla, founder of ZICO Coconut Water and the author of The Entrepreneur’s Guide to Freedom, to join us on The AGEIST Podcast. He challenges the relentless drive that defines most entrepreneurial lives by opening up about the emotional and physical toll his hustle took and how he rebuilt his life around energy, discipline, and self-awareness. Mark also shares the surprising tools and mindset shifts that helped him regain not just balance, but meaning—and how others can do the same.

How long will you live? Take our quiz today to find out at ageist.com/longevity-quiz!

Special Thanks to Our Sponsors

Timeline Nutrition: Our favorite supplement for cell support and mitochondrial function. Listeners can now get 20% off their first Timeline purchase by using the code “AGEIST” at checkout at TimelineNutrition.com/ageist.

Maui Nui: The cleanest, most nutrient-dense red meat out there—high in protein, rich in antioxidants, and ethically harvested. Their new, subscription-only ‘Ohana Reserve Aged Cuts are aged for 14 days to make for unforgettable flavor, plus their to-go venison sticks are perfect for healthy snacking. Right now, Maui Nui is offering a free 12-pack of their jerky sticks with your first order of $79 or more. Just go to mauinuivenison.com/ageist to grab yours.

LMNT Electrolytes: Our #1 electrolytes for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

Key Moments

“I realized I was still trapped—working crazy hours, drinking too much, my marriage falling apart—and I thought, this is success?”

“Energy is the most valuable resource I believe we have. I build my life around it.”

“Your company’s growth is highly correlated with your own personal growth.”

Connect with Mark Rampolla

Website

LinkedIn

Project Regeneration

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Click Here for the full interview transcript.

Say hi to the AGEIST team!

This week, spiritual wellness expert Adam Smith joins us from Canyon Ranch to talk about finding calm and clarity in today’s chaotic world. With clinical pastoral training and years of experience supporting people through trauma and hospice care, Adam offers practical ways to build presence, reduce anxiety, and develop spiritual resilience. He explains why embracing uncertainty can be more powerful than chasing control, plus how practices like walking meditation, mindfulness, and curiosity help. Whether you're struggling with burnout, seeking deeper meaning, or just want to feel more alive, this conversation is full of tools to help you reconnect.

How long will you live? Take our quiz today to find out at ageist.com/longevity-quiz!

Special Thanks to Our Sponsors

LMNT Electrolytes: Our #1 electrolytes for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

Timeline Nutrition: Our favorite supplement for cell support and mitochondrial function. Listeners can now get 20% off their first Timeline purchase by using the code “AGEIST” at checkout at TimelineNutrition.com/ageist.

Maui Nui: The cleanest, most nutrient-dense red meat out there—high in protein, rich in antioxidants, and ethically harvested. Their new, subscription-only ‘Ohana Reserve Aged Cuts are aged for 14 days to make for unforgettable flavor, plus their to-go venison sticks are perfect for healthy snacking. Right now, Maui Nui is offering a free 12-pack of their jerky sticks with your first order of $79 or more. Just go to mauinuivenison.com/ageist to grab yours.

Key Moments
"Choose uncertainty over worry. It’s actually not a bad thing to not know, if we can allow it."

"Flow state is an absolute cooperation with the inevitable."

"It's very important that you do unimportant things. Otherwise, you can get dead serious."

Connect with Adam Smith
Canyon Ranch

Sign up for the LONGEVITY8 Retreat with Adam and David

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Click Here for the full interview transcript.

Say hi to the AGEIST team!

Heidi Clements and Constance Zimmer, co-hosts of the podcast Talk 50 to Me, are rewriting the rules of midlife and aging out loud. In this bold, unfiltered conversation, they unabashedly talk about why women over 50 are finally done staying quiet and what real empowerment looks like. From dismantling anti-aging myths to calling out the beauty industry’s obsession with youth, Heidi and Constance offer insights that are both rebellious as well as deeply inspiring and practical. So if you’ve ever felt unseen or unsure about aging, this episode delivers a refreshing, no-holds-barred perspective.

How long will you live? Take our quiz today to find out at ageist.com/longevity-quiz!

Special Thanks to Our Sponsors

fatty15: C15:0 is the first essential fatty acid to be discovered in over 90 years, and fatty15 is on a mission to optimize your C15:0 levels to help support your long-term health and wellness—especially as you age. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/AGEIST and using the code “AGEIST” at checkout.

LMNT Electrolytes: Our #1 electrolytes for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

Timeline Nutrition: Our favorite supplement for cell support and mitochondrial function. Listeners can now get 20% off their first Timeline purchase by using the code “AGEIST” at checkout at TimelineNutrition.com/ageist.

Key Moments
“We want to change the way the world looks at women over 50, and we want to change the way women over 50 look at themselves.”

“I think the friendships that you form after 50 are all about the quality of time together, not the quantity.”

“Putting yourself first is considered selfish—but I’m trying to disappoint myself less.”

Connect with Heidi and Constance

Heidi's Instagram (@welcometoheidi)

Constance’s Instagram (@constancezimmer)

Talk Fifty to Me Instagram (@talkfiftytome)

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Click Here for the full interview transcript.

Cybroc

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Can controlling your mind control your health? This week on The AGEIST Podcast, we revisit a powerful episode from the archives. Dr. David Spiegel, one of the world’s leading experts on hypnosis and psycho-oncology, explains how stress, sleep, and emotional regulation directly influence survival, especially in cancer patients. He also shares how self-hypnosis and structured breathing can reduce pain, anxiety, and even tremors—tools now made widely accessible through his app, Reveri. Optimize your autonomic nervous system to sleep better, feel calmer, and potentially live longer.

How long will you live? Take our quiz today to find out at ageist.com/longevity-quiz!

Special Thanks to Our Sponsors
Ozlo Sleepbuds: Transform your nights with science-backed wearables designed to help you fall asleep faster, stay asleep longer, and wake up restored. Now through October 16th, save $50 when you use our link.

fatty15: C15:0 is the first essential fatty acid to be discovered in over 90 years, and fatty15 is on a mission to optimize your C15:0 levels to help support your long-term health and wellness—especially as you age. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/AGEIST and using the code “AGEIST” at checkout.

LMNT Electrolytes: Our #1 electrolytes for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

Key Moments
“The strain in pain lies mainly in the brain.”

“We have not succeeded in killing anybody with hypnosis yet.”

“Good sleep at night should be a part of everybody’s health regimen, but especially cancer patients.”

Connect with Dr. Spiegel

Reveri App

Stanford Healthcare Profile

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Read the full interview transcript here or at ageist.com

Say hi to the AGEIST team!

What if one simple molecule could improve your energy, brain clarity, hormone balance, and heart health? Functional nutritionist Dr. Cathy Eason joins us on The AGEIST Podcast to share why nitric oxide (NO) is an often-overlooked key to healthy aging, and how most people over 35 are deficient. She breaks down how testing your levels is a quick, simple way to know your NO levels (it only takes 15 seconds), as well as how to increase your NO through diet, lifestyle, and a clinically tested supplement. Plus, Dr. Eason also reveals why common habits like mouthwash and over-exercising may be silently sabotaging your health goals. Tune in to learn how it all connects.

How long will you live? Take our quiz today to find out at ageist.com/longevity-quiz!

Special Thanks to Our Sponsors
Berkeley Life: Boost your energy, support heart health, and improve circulation with Berkeley Life Nitric Oxide. Use code AGEIST at berkeleylife.com for 20% off your first purchase–plus 10 free test strips to track your progress.

Maui Nui: The cleanest, most nutrient-dense red meat out there—high in protein, rich in antioxidants, and ethically harvested. Their new, subscription-only Ohana Reserve Aged Cuts are aged for 14 days to make for unforgettable flavor, plus their to-go venison sticks are perfect for healthy snacking. Right now, Maui Nui is offering a free 12-pack of their jerky sticks with your first order of $79 or more. Just go to mauinuivenison.com/ageist to grab yours.

Ozlo Sleepbuds: Transform your nights with science-backed wearables designed to help you fall asleep faster, stay asleep longer, and wake up restored. Now through September 30th, save $50 when you use our link.

Key Moments

“There is not a system in the body that nitric oxide does not touch.”

“As estrogen declines, what happens to nitric oxide production is it dramatically drops at the same time.”

“When we boost blood flow, we boost the ability of red blood cells to carry oxygen to the tissues that need them.”

Connect with Dr. Eason

Website (Berkeley Life)

Instagram (@berkeleylifeno)

LinkedIn

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Click Here for the full interview transcript.

Say hi to the AGEIST team!

This week, we welcome Dr. Chris Renna back to The AGEIST Podcast to break down one of the most hyped but least understood subjects in modern health: stem cells. Along with providing a clear explanation of how different types of stem cells function, he talks about how they interact with our immune systems and why most “stem cell therapies” people hear about are missing the point. Tune in to learn what actually works, the difference between redeploying vs. reloading stem cells, and the critical importance of starting any anti-aging protocol by age 30. For those of us interested in real longevity—not just the buzzwords—this episode delivers grounded, usable knowledge.

How long will you live? Take our quiz today to find out at ageist.com/longevity-quiz!

Special Thanks to Our Sponsors
Berkeley Life: Boost your energy, support heart health, and improve circulation with Berkeley Life Nitric Oxide. Use the code “AGEIST” at berkeleylife.com for 20% off your first purchase—plus 10 free test strips to track your progress.

Ozlo Sleepbuds: Transform your nights with science-backed wearables designed to help you fall asleep faster, stay asleep longer, and wake up restored. Now through September 30th, save $50 when you use our link: https://ozlosleep.com/?tw_source=ageist&utm_source=ageist&utm_medium=newsletter&utm_campaign=september-2025

Maui Nui: The cleanest, most nutrient-dense red meat out there—high in protein, rich in antioxidants, and ethically harvested. Their new, subscription-only ‘Ohana Reserve Aged Cuts are aged for 14 days to make for unforgettable flavor, plus their to-go venison sticks are perfect for healthy snacking. Right now, Maui Nui is offering a free 12-pack of their jerky sticks with your first order of $79 or more. Just go to mauinuivenison.com/ageist to grab yours.

Key Moments
“Healing proceeds as inflammation recedes.”

“You’re not enhancing your stem cell population—you’re just renting anti-inflammatories for four months.”

“A serious undertaking of anti-aging strategies becomes unquestionably necessary at the age of 30.”

Connect with Dr. Chris Renna
Website (Lifespan Medicine)

Email: info@lifespanmedicine.com

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Click Here for the full interview transcript.

Say hi to the AGEIST team!