Weight Loss Science

“Eat less, move more” is incomplete. You can lose weight eating more. How? Through a process known as diet-induced thermogenesis. Diet-induced thermogenesis, the calories burned digesting and absorbing the food you eat, has a greater impact on “calories-out” than exercise. But when you restrict your caloric intake, you restrict diet-induced thermogenesis. Thus, the principle of weight loss is not consuming a very small number of calories - especially when “calories-in” increases “calories-out”.

In January 2023, bestselling author Johann Hari started to inject himself once a week with Ozempic, the diabetes drug that produces significant weight loss. He wasn’t alone—credible predictions suggest that in two years, a quarter of the U.S. population will be taking this class of drug. Proponents say that this is a biological solution to a biological problem. While 95 percent of diets fail, the average person taking one of the new drugs will lose a quarter of their body weight in six months, and keep it off for as long as they take it.

When it comes to setting and achieving your goals, how you think influences what you do. Whether developing a sustainable relationship with food, jump-starting a new fitness routine to shoot for a certain number on the scale, or tackling a health issue, mindset is key to meeting your goals—but it can also often be the most neglected element in any attempt to change behavior. While you might know what you want to do, the key to success is understanding why you want to do it, and how you make a plan that works for you in the long term.

Calorie information is ubiquitous. We see authoritative numbers that tell us the calorie count of what we're about to consume everywhere. Here's the thing, however, that most people have no idea about. All of the calorie counts that you see everywhere today, are wrong. Dr Giles Yeo, obesity researcher at Cambridge University, challenges the conventional model and demonstrates that all calories are not created equal. He addresses why popular diets succeed, at least in the short term, and why they ultimately fail, and what your environment has to do with your bodyweight.

Discover the cutting-edge science behind long-term weight loss success in this powerful new audiobook from the New York Times best-selling author of How Not to Die.

Over the next five years, millions of more Americans are expected to take Ozempic and other GLP-1 weight-loss drugs, which are rapidly being recognized as the miracle drugs of this century. If you’re not on them, you’ll probably know someone who is. What are the implications of the widespread use of these drugs, both on our bodies and our society? In this show, you’ll meet people across America who are either taking the jab or thinking about it, and the shocking intentional and unintentional results they are seeing.

The vast majority of premature deaths can be prevented through simple changes in diet and lifestyle. In How Not to Die, Dr. Michael Greger, the internationally-renowned nutrition expert, physician, and founder of NutritionFacts.org, examines the fifteen top causes of premature death in America-heart disease, various cancers, diabetes, Parkinson's, high blood pressure, and more-and explains how nutritional and lifestyle interventions can sometimes trump prescription pills and other pharmaceutical and surgical approaches, freeing us to live healthier lives.

Does losing weight and staying healthy feel like a battle? Well, it's really a war. Your enemies are your own genes, backed by millions of years of evolution, and the only way to win is to outsmart them. From the renowned surgeon and founder of Gundry MD, this revolutionary book shares the health secrets other doctors won't tell you.

Gut Reactions by chemist Simon Quellen Field shows us how our bodies react to food and the environment, and how our brain affects what and how much we eat, and in turn, is affected by what we eat. It shows why some diets work for some people but not for others, based on genetics, previous weight history, brain chemistry, environmental cues, and social pressures. It explores how dozens of hormones affect hunger and satiety and interact with the brain and the gut to regulate feeding behavior.

No one wants to overeat. And certainly no one wants to overeat for years, become overweight, and end up with a high risk of diabetes or heart disease--yet two thirds of Americans do precisely that. Even though we know better, we often eat too much. Why does our behavior betray our own intentions to be lean and healthy? The problem, argues obesity and neuroscience researcher Stephan J. Guyenet, is not necessarily a lack of willpower or an incorrect understanding of what to eat.

Through a compassionate lens, Metabolism Repair for Women explores how both eating behavior and energy expenditure are not under conscious control. Instead, they’re subject to the brain’s regulatory mechanism. And if you have metabolic dysfunction (i.e., insulin resistance, hypoglycemia, and/or weight gain), it’s because something is amiss with that regulatory mechanism.

If you’re feeling frustrated or scared based on a PCOS diagnosis or symptoms you’re experiencing, take comfort in knowing that a change in the way you eat has been shown to significantly improve common symptoms associated with polycystic ovarian syndrome and has often helped restore fertility to those afflicted with the condition. Recent studies have found associations with a variety of macronutrients, supplements, and foods that can positively and negatively affect your PCOS symptoms.

For many women, body goals are all about loss. In Give Yourself More, leading health experts Georgie Fear and K. Aleisha Fetters draw on psychology, cultural studies, and the science of behavioral change to reveal how the pursuit of less gets women very little. They teach you how to flip the script on losing mind-sets, so you can change your body and life for the positive.

The bestselling fitness book for women who want to lose up to 35 pounds of fat or more and gain whole-body muscle definition in just 3-5 hours per week—and without giving up delicious foods or doing grueling workouts.

In this book, Susan Peirce Thompson, Ph.D., shares the groundbreaking weight-loss solution based on her highly acclaimed Bright Line Eating Boot Camps. Rooted in cutting-edge neuroscience, psychology, and biology, Bright Line Eating explains why people who are desperate to lose weight fail again and again: It’s because the brain blocks weight loss.

From a Pulitzer Prize-winning investigative reporter at The New York Times comes the explosive story of the rise of the processed food industry and its link to the emerging obesity epidemic. Michael Moss reveals how companies use salt, sugar, and fat to addict us and, more important, how we can fight back.

From her office in the University of Minnesota's Health and Eating Lab, professor Traci Mann researches self-control and dieting. And what she has discovered is groundbreaking. Not only do diets not work, they often result in weight gain. Americans are losing the battle of the bulge because our bodies and brains are not hardwired to resist food - the very idea of it works against our biological imperative to survive.

Your Body in Balance provides step-by-step guidance for understanding what's at the root of your suffering - and what you can do to feel better fast. Few people realize that a simple food prescription can help you tackle all these and more by gently restoring your hormone balance, with benefits rivaling medications. Neal Barnard, MD, a leading authority on nutrition and health, offers insight into how dietary changes can alleviate years of stress, pain, and illness. What's more, he also provides delicious and easy-to-make hormone-balancing recipes.

Among Americans, diabetes is more prevalent today than ever. Obesity is at epidemic proportions; nearly 10% of children are thought to have nonalcoholic fatty liver disease. And sugar is at the root of these, and other, critical, society-wide, health-related problems. With his signature command of both science and straight talk, Gary Taubes delves into Americans' history with sugar: its uses as a preservative, as an additive in cigarettes, the contemporary overuse of high-fructose corn syrup.

Building upon this critical work in Good Calories, Bad Calories and presenting fresh evidence for his claim, Taubes now revisits the urgent question of what's making us fat - and how we can change - in this exciting new book. Persuasive, straightforward, and practical, Why We Get Fat makes Taubes' crucial argument newly accessible to a wider audience.