Physical Biology

Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer who worked the same land as her slave ancestors, yet her cells - taken without her knowledge - became one of the most important tools in medicine: The first “immortal” human cells grown in culture, which are still alive today, though she has been dead for more than 60 years. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects.

In Cancer and the New Biology of Water, Thomas Cowan argues that this failure was inevitable because the oncogene theory is incorrect or at least incomplete and based on a flawed concept of biology in which DNA controls our cellular function and therefore our health. Instead, Dr. Cowan tells us the somatic mutations seen in cancer cells are the result of a cellular deterioration that has little to do with oncogenes, DNA, or even the nucleus.

We may believe that we are the masters of our fates, but in reality, we are at the mercy of hundreds of trillions of single-celled organisms that exert control over every aspect of how our minds and bodies function. These are the diverse species of microbes that work together synergistically to communicate with each other and with every system in our bodies. You are your microbiome’s home, and it wants to take care of you, but first you have to protect it. In Gut Check, Dr. Steven Gundry reveals the emerging science proving that Hippocrates was right—all disease begins in the gut.

Biogeography is the study of geographic variation in all characteristics of life - ranging from genetic, morphological, and behavioral variation among regional populations of a species, to geographic trends in diversity of entire communities across our planet's surface. From the ancient hunters and gatherers to the earliest naturalists, Charles Darwin, Alfred Russel Wallace, and scientists today, the search for patterns in life has provided insights that proved invaluable for understanding the natural world.

A magnificently reported and soulfully crafted exploration of the human immune system - the key to health and wellness, life and death. An epic, first-of-its-kind audiobook, entwining leading-edge scientific discovery with the intimate stories of four individual lives, by the Pulitzer Prize-winning New York Times journalist.

The emotional trauma we suffer as children not only shapes our emotional lives as adults but also affects our physical health and overall well-being. Scientists now know on a biochemical level exactly how parents' chronic fights, divorce, death in the family, being bullied or hazed, and growing up with a hypercritical, alcoholic, or mentally ill parent can leave permanent, physical "fingerprints" on our brains.

Until recently, microglia were thought to be merely the brain’s housekeepers, helpfully removing damaged cells. But a recent groundbreaking discovery revealed them to be capable of terrifying Jekyll and Hyde behavior. When triggered - and anything that stirs up the immune system in the body can activate microglia - they can morph into destroyers, impacting a wide range of issues from memory problems and anxiety to depression and Alzheimer’s. Under the right circumstances, however, microglia can be coaxed back into being angelic healers.

As dramatic as The Double Helix and as absorbing as The Soul of a New Machine, Natural Obsessions explores the advanced reaches of molecular biology, the nature of the human cell, and the genes that control cancer. It unforgettably portrays some of the best young scientists in the world, the rewards and discouragements of scientific research, and the very process of scientific inquiry.

With curiosity and wit, Ina Park's Strange Bedfellows rips back the sheets on the mysteries of what happens when STDs enter the sack.

We have lost the war on cancer. We spend $150 billion each year treating it, yet - a few innovations notwithstanding - a patient with cancer is as likely to die of it as one was 50 years ago. Most new drugs add mere months to one's life at agonizing physical and financial cost. In The First Cell, Azra Raza offers a searing account of how both medicine and our society (mis)treats cancer, how we can do better, and why we must.

Cystic fibrosis was once a mysterious disease that killed infants and children. Now it could be the key to healing millions with genetic diseases of every type - from Alzheimer's and Parkinson's to diabetes and sickle cell anemia. Told from the perspectives of the patients, families, physicians, scientists, and philanthropists fighting on the front lines, Breath from Salt is a remarkable story of unlikely scientific and medical firsts, of setbacks and successes, and of people who refused to give up hope....

We humans like to think of ourselves as highly evolved creatures. But if we are supposedly evolution's greatest creation, why do we have such bad knees? Why do we catch head colds so often - 200 times more often than a dog does? How come our wrists have so many useless bones? And are we really supposed to swallow and breathe through the same narrow tube? Surely there's been some kind of mistake. As professor of biology Nathan H. Lents explains in Human Errors, our evolutionary history is nothing if not a litany of mistakes, each more entertaining and enlightening than the last.

An award-winning scientist offers a groundbreaking new understanding of the mind-body connection and its profound impact on everything from advertising to romance. The human body is not just a passive device carrying out messages sent by the brain but rather an integral part of how we think and make decisions.

Millions of Americans suffer from hearing loss. Faced with the cost and stigma of hearing aids, the natural human tendency is to do nothing and hope for the best, usually while pretending that nothing is wrong. In Volume Control, David Owen argues this inaction comes with a huge social cost. He demystifies the science of hearing while encouraging listeners to get the treatment they need for hearing loss and protect the hearing they still have.

Elegantly written and deeply grounded in personal experience - works by Oliver Sacks come to mind - Physical Intelligence gives us a clear, illuminating examination of the intricate, mutually responsive relationship between the mind and the body as they engage (or don’t engage) in all manner of physical action. Ever wonder why you don’t walk into walls or off cliffs? How you decide if you can drive through a snowstorm? How high you are willing to climb up a ladder to change a lightbulb?

In spring of 1918, World War I was underway, and troops at Fort Riley, Kansas, found themselves felled by influenza. By the summer of 1918, the second wave struck as a highly contagious and lethal epidemic and within weeks exploded into a pandemic, an illness that travels rapidly from one continent to another. It would impact the course of the war, and kill many millions more soldiers than warfare itself.

The form and function of a sprinting cheetah are quite unlike those of a rooted tree. A human being is very different from a bacterium or a zebra. The living world is a realm of dazzling variety, yet a shared set of physical principles shapes the forms and behaviors of every creature in it. So Simple a Beginning shows how the emerging new science of biophysics is transforming our understanding of life on Earth and enabling potentially lifesaving but controversial technologies such as gene editing, artificial organ growth, and ecosystem engineering.

Flush is both an urgent exploration of the world’s single most squandered natural resource, and a cri de coeur (or cri de colon?) for the vast, hidden value in our “waste.” Award-winning journalist and microbiologist Bryn Nelson, PhD, leads listeners through the colon and beyond with infectious enthusiasm, helping to usher in a necessary mental shift that could restore our balance with the rest of the planet and save us from ourselves.

Demystifying Cancer Biology is a mini-textbook with a difference - using clear, easy-to-understand language, this audiobook will break down the barriers to understanding the complex world of the cellular and molecular biology of cancer.

The human body is like an exceedingly well-fortified castle, defended by billions of soldiers - some live for less than a day, others remember battles for decades, but all are essential in protecting us from disease. This hidden army is our immune system, and without it we could not survive the eternal war between us and our microscopic enemies. Immune explores the incredible arsenal that lives within us - how it knows what to attack and what to defend and how it kills everything from the common cold to the plague bacterium.