A small Georgia town erupts in panic when a young college professor is found brutally mutilated in the local diner. But it's only when town pediatrician and coroner Sara Linton does the autopsy that the full extent of the killer's twisted work becomes clear. Sara's ex-husband, Police Chief Jeffrey Tolliver, leads the investigation - a trail of terror that grows increasingly macabre when another local woman is found crucified a few days later.

From Atlanta's wealthiest suburbs to its stark inner-city housing projects, a killer has crossed the boundaries of wealth and race. And the people who are chasing him must cross those boundaries, too. Among them is Michael Ormewood, a veteran detective whose marriage is hanging by a thread and whose arrogance and explosive temper are threatening his career. And Angie Polaski, a beautiful vice cop who was once Michael's lover before she became his enemy.

Sisters. Strangers. Survivors. More than 20 years ago, Claire and Lydia's teenaged sister Julia vanished without a trace. The two women have not spoken since, and now their lives could not be more different. Claire is the glamorous trophy wife of an Atlanta millionaire. Lydia, a single mother, dates an ex-con and struggles to make ends meet. But neither has recovered from the horror and heartbreak of their shared loss—a devastating wound that's cruelly ripped open when Claire's husband is killed.

At the age of 13, Charlie Quinn's childhood came to an abrupt and devastating end. Two men, with a grudge against her lawyer father, broke into Charlie's home - and after that shocking night, her world was never the same. Now a lawyer herself, Charlie has made it her mission to defend those with no one else to turn to.

Angela's graduate school days at MIT come to an abrupt end when she uses her hacking skills on another student's computer. Yet her mentor, Eve Abajian, arranges a new beginning for her - as an intern in FBI's Boston field office. Her new supervisor, Assistant Special Agent in Charge William Keats, one of only two agents in the Northeast to make his rank before the age of 30, sees in Angela a fellow prodigy. But Angela's skills come with a natural curiosity, which is also a dangerous liability.