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Keep Sharp

How to Build a Better Brain at Any Age

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Keep Sharp

Written by: Sanjay Gupta M.D. M.D.
Narrated by: Sanjay Gupta M.D. M.D.
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$8.99/mo. after 3 months. Cancel anytime. Offer ends July 15, 2026 at 11:59pm PT.

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Keep your brain young, healthy, and sharp with this science-driven guide to protecting your mind from decline by neurosurgeon and CNN chief medical correspondent Dr. Sanjay Gupta.

Throughout our life, we look for ways to keep our minds sharp and effortlessly productive. Now, globetrotting neurosurgeon Dr. Sanjay Gupta offers “the book all of us need, young and old” (Walter Isaacson, #1 New York Times bestselling author of The Code Breaker) with insights from top scientists all over the world, whose cutting-edge research can help you heighten and protect brain function and maintain cognitive health at any age.

Keep Sharp debunks common myths about aging and mental decline, explores whether there’s a “best” diet or exercise regimen for the brain, and explains whether it’s healthier to play video games that test memory and processing speed, or to engage in more social interaction. Discover what we can learn from “super-brained” people who are in their eighties and nineties with no signs of slowing down—and whether there are truly any benefits to drugs, supplements, and vitamins. Dr. Gupta also addresses brain disease, particularly Alzheimer’s, answers all your questions about the signs and symptoms, and shows how to ward against it and stay healthy while caring for a partner in cognitive decline. He likewise provides you with a personalized twelve-week program featuring practical strategies to strengthen your brain every day.

Keep Sharp is the “must-read owner’s manual” (Arianna Huffington) you’ll need to keep your brain young and healthy regardless of your age!
Memory Improvement Personal Development Psychology Psychology & Mental Health Human Brain Dementia Health Aging Parent Mental Health Nutrition Physical Exercise Alzheimer's Disease Aging Medicine Longevity Smart Brain

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What the critics say

“A must-read owner’s manual for anyone with a brain.”
—Arianna Huffington, Founder & CEO, Thrive Global
“Dr. Sanjay Gupta has the unique ability to translate the latest scientific research into accessible language we can all understand. Whether you’re concerned about memory loss or simply want to boost your mental acuity, Keep Sharp is an essential guide.”
—Gary Small, MD, Director, UCLA Longevity Center
“Gupta is brilliant at busting myths, allaying fears, and giving us the solutions we need to keep sharp throughout our lives.”
—Dean Ornish, MD, Founder & President, Preventive Medicine Research Institute
“This is a frontier where we can dramatically improve human life, and Keep Sharp is a helpful primer for anyone who wants to better understand brain function and how to preserve it.”
— Bill Gates, Co-Chair, Bill & Melinda Gates Foundation
Keep Sharp will change how you think about your brain, how you care for it, and how you support its full potential.”
David B. Agus, MD, New York Times bestselling author of The End of Illness
“This is the book all of us need, young and old!”
—Walter Isaacson, New York Times bestselling author of Steve Jobs
“Sanjay Gupta brilliantly crafts an actionable plan we can all follow. I feel sharper already.”
—Mehmet Oz, MD, Host, The Dr. Oz Show
Keep Sharp shows it’s absolutely possible to take control of one’s brain health for life.”
Richard Isaacson, MD, Director, Alzheimer’s Prevention Clinic at the Weill Cornell Memory Disorders Program
“In a steady, measured voice, [Gupta] presents a comprehensive view of the best that brain science has to offer to preserve and improve memory… A genuine source of practical knowledge and sympathy to those struggling with dementia and the family members who are primary caregivers.”
Kirkus Reviews
“[Gupta’s] optimism and the wealth of scientific information he corrals will embolden and comfort readers.”
Publishers Weekly
All stars
Most Relevant
This is a great book! Valuable information for building a better brain for life :)

Great read important information!

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Very informative. Sanjay Gupta covered a lot of interesting information and I know I will review it again because there is a lot of good information and tips. I understand so much more now. Definitely recommend.


Excellent read

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This is a book that I will read and re-read. Dr. Gupta has such a knack of explaining concepts and principles to lay people. That is his gift to the world. Keep Sharp is a guide that will help millions across the globe maintain hope and mental acumen as long as they possibly can. Thank you again Dr.

Excellent

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I enjoyed every part of this book. Sanjay was spot on in many aspects on how we should look after ourselves. The brain 🧠 is vital to our existence and it's great to learn how we can look after it. Congratulations, Sanjay!

Remarkably written and narrated

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The book is full of hope, backed by knowledge that is supported by facts. A eye opener to anyone at any stage of their life with any health condition.
So Positive & very Insperational!
Thank you Sanjay & Team!

A life changer!

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